Role of

RT-PCR atrophic scar hTERT hypertrophic scar single nucleotide polymorphism

Journal

Experimental and therapeutic medicine
ISSN: 1792-1015
Titre abrégé: Exp Ther Med
Pays: Greece
ID NLM: 101531947

Informations de publication

Date de publication:
Apr 2022
Historique:
received: 26 07 2021
accepted: 25 08 2021
entrez: 7 3 2022
pubmed: 8 3 2022
medline: 8 3 2022
Statut: ppublish

Résumé

Hypertrophic and atrophic scars are the effect of a dysregulated wound-healing process in genetically predisposed individuals. The genetic predisposition has acquired significant attention due to the diverse phenotype of pathological scarring in individuals with a positive personal and family history. Recent studies have identified telomere shortening and decreased hTERT activity in pathological scarring, proposing the rs2736100 variant of human telomerase reverse transcriptase (

Identifiants

pubmed: 35251326
doi: 10.3892/etm.2022.11186
pii: ETM-0-0-11186
pmc: PMC8892623
doi:

Types de publication

Journal Article

Langues

eng

Pagination

260

Informations de copyright

Copyright © 2020, Spandidos Publications.

Déclaration de conflit d'intérêts

The authors declare that they have no competing interests.

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Auteurs

Roxana Flavia Ilieș (RF)

Department of Medical Genetics, 'Iuliu Hațieganu' University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.

Salomea-Ruth Halmagyi (SR)

Department of Medical Genetics, 'Iuliu Hațieganu' University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.

Andreea Cătană (A)

Department of Medical Genetics, 'Iuliu Hațieganu' University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.
Department of Oncogenetics, 'Ion Chiricuță' Oncological Institute, 400015 Cluj-Napoca, Romania.

Casian Simon Aioanei (CS)

Department of Medical Genetics, 'Iuliu Hațieganu' University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.

Istvan Lukacs (I)

1st Department of Obstetrics and Gynecology, 'Iuliu Hațieganu' University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.

Reka-Eniko Tokes (RE)

1st Department of Obstetrics and Gynecology, 'Iuliu Hațieganu' University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.

Ioana Cristina Rotar (IC)

1st Department of Obstetrics and Gynecology, 'Iuliu Hațieganu' University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.
1st Clinic of Obstetrics and Gynecology, Emergency County Hospital, 400006 Cluj-Napoca, Romania.

Ioan Victor Pop (IV)

Department of Medical Genetics, 'Iuliu Hațieganu' University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.

Classifications MeSH