Maresins: The Mainstay in Periodontal Resolution.
inflammation
macrophage
maresins
periodontitis
resolution
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
Jan 2022
Jan 2022
Historique:
accepted:
30
01
2022
entrez:
7
3
2022
pubmed:
8
3
2022
medline:
8
3
2022
Statut:
epublish
Résumé
Not much was known about the resolution of inflammation until the recent past when significant breakthroughs led to the unveiling of the exact mechanism of this. It is now known that the resolution of inflammation involves specific mediators of resolution such as lipoxins, protectins, resolvins, and maresins, making it an active process. Of these mediators, maresins are the latest discovery. Maresins are macrophage-derived mediators that are involved in the resolution of inflammation. Various studies on what maresins do to resolve periodontitis are ongoing. Reportedly, maresins help in periodontal regeneration and wound healing. Having known the numerous roles of these mediators, our current focus is shifting from anti-inflammatory pharmacotherapy to resolution pharmacotherapy.
Identifiants
pubmed: 35251814
doi: 10.7759/cureus.21742
pmc: PMC8888070
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
e21742Informations de copyright
Copyright © 2022, Gireddy et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
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