Anti-aging effects of chlorpropamide depend on mitochondrial complex-II and the production of mitochondrial reactive oxygen species.
ATP sensitive potassium channels
Anti-aging
Chlorpropamide
Mitochondrial complex II
Mitochondrial reactive oxygen species
Senescence
Succinate dehydrogenase
Sulfonylureas
Journal
Acta pharmaceutica Sinica. B
ISSN: 2211-3835
Titre abrégé: Acta Pharm Sin B
Pays: Netherlands
ID NLM: 101600560
Informations de publication
Date de publication:
Feb 2022
Feb 2022
Historique:
received:
23
05
2021
revised:
22
07
2021
accepted:
30
07
2021
entrez:
8
3
2022
pubmed:
9
3
2022
medline:
9
3
2022
Statut:
ppublish
Résumé
Sulfonylureas are widely used oral anti-diabetic drugs. However, its long-term usage effects on patients' lifespan remain controversial, with no reports of influence on animal longevity. Hence, the anti-aging effects of chlorpropamide along with glimepiride, glibenclamide, and tolbutamide were studied with special emphasis on the interaction of chlorpropamide with mitochondrial ATP-sensitive K
Identifiants
pubmed: 35256938
doi: 10.1016/j.apsb.2021.08.007
pii: S2211-3835(21)00297-5
pmc: PMC8897034
doi:
Types de publication
Journal Article
Langues
eng
Pagination
665-677Informations de copyright
© 2022 Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences. Production and hosting by Elsevier B.V.
Références
Science. 2016 Jun 17;352(6292):1436-43
pubmed: 27127236
Proc Natl Acad Sci U S A. 2004 Aug 10;101(32):11880-5
pubmed: 15284438
Sci Rep. 2019 Sep 16;9(1):13364
pubmed: 31527593
PLoS Biol. 2010 Dec 07;8(12):e1000556
pubmed: 21151885
Free Radic Biol Med. 2013 Apr;57:188-200
pubmed: 23000260
Environ Pollut. 2021 May 15;277:115904
pubmed: 33714130
Lancet. 1985 Aug 31;2(8453):474-5
pubmed: 2412077
Nat Rev Mol Cell Biol. 2016 Apr;17(4):213-26
pubmed: 26956194
Acta Pharm Sin B. 2019 Mar;9(2):279-293
pubmed: 30972277
Trends Cell Biol. 2011 Oct;21(10):569-76
pubmed: 21824781
Curr Biol. 2010 Dec 7;20(23):2131-6
pubmed: 21093262
Oxid Med Cell Longev. 2017;2017:3451528
pubmed: 28337248
Nat Commun. 2013;4:2192
pubmed: 23900241
Methods Mol Biol. 2016;1473:17-22
pubmed: 27518619
Nature. 2014 Jan 16;505(7483):335-43
pubmed: 24429632
Biochim Biophys Acta Bioenerg. 2018 May;1859(5):309-318
pubmed: 29458000
J Biol Chem. 1996 Apr 12;271(15):8796-9
pubmed: 8621517
Diabetologia. 2015 Jul;58(7):1532-41
pubmed: 25874444
Cell Metab. 2012 Apr 4;15(4):451-65
pubmed: 22482728
Cell. 2017 Mar 23;169(1):132-147.e16
pubmed: 28340339
Toxicol Sci. 2016 Aug;152(2):349-62
pubmed: 27208080
J Gerontol A Biol Sci Med Sci. 2017 Apr 1;72(4):473-480
pubmed: 28158466
Molecules. 2018 Jun 05;23(6):
pubmed: 29874836
JAMA. 2019 Sep 24;322(12):1147-1149
pubmed: 31536110
Proc Natl Acad Sci U S A. 2014 Oct 21;111(42):E4458-67
pubmed: 25288734
Phytother Res. 2001 Aug;15(5):456-8
pubmed: 11507745
Nature. 1991 Jul 18;352(6332):244-7
pubmed: 1857420
Nature. 2013 May 23;497(7450):451-7
pubmed: 23698443
PLoS Genet. 2015 Feb 11;11(2):e1004972
pubmed: 25671321
Aging Cell. 2010 Aug;9(4):490-505
pubmed: 20497132
Basic Res Cardiol. 2009 Mar;104(2):121-9
pubmed: 19242645
Biochim Biophys Acta. 2008 Jul-Aug;1777(7-8):882-9
pubmed: 18433712
Genome Biol. 2001;2(1):RESEARCH0002
pubmed: 11178279
Acta Biochim Pol. 1996;43(4):713-9
pubmed: 9104509
Cell. 2005 Jul 1;121(7):1043-57
pubmed: 15989954
Nature. 2019 Feb;566(7742):73-78
pubmed: 30728521
Nature. 2017 Nov 8;551(7679):198-203
pubmed: 29120414
Redox Biol. 2017 Apr;11:365-374
pubmed: 28043053
J Biol Chem. 2012 Aug 3;287(32):27255-64
pubmed: 22689576
Oxid Med Cell Longev. 2019 Nov 15;2019:6840540
pubmed: 31827694
J Pharm Sci. 1987 May;76(5):366-70
pubmed: 3656098
J Pak Med Assoc. 2015 Jan;65(1):101-4
pubmed: 25831689
Free Radic Biol Med. 2015 Dec;89:486-97
pubmed: 26453927
Nature. 2019 Aug;572(7771):609-613
pubmed: 31435016
Exp Neurol. 1996 Mar;138(1):15-21
pubmed: 8593890
Antioxid Redox Signal. 2021 May 10;34(14):1069-1082
pubmed: 33270507
Pflugers Arch. 1995 May;430(1):44-54
pubmed: 7667078
Cell. 2014 May 8;157(4):882-896
pubmed: 24813611
J Biol Chem. 1992 Dec 25;267(36):26062-9
pubmed: 1464617
Diabetes Res Clin Pract. 2019 Nov;157:107836
pubmed: 31479704
J Biol Chem. 2010 Aug 20;285(34):26494-505
pubmed: 20566649
Exp Neurol. 2018 Nov;309:67-78
pubmed: 30076829
Nature. 2019 Jul;571(7764):183-192
pubmed: 31292558
Diabetes Care. 2017 May;40(5):629-631
pubmed: 28428320
Trends Biochem Sci. 2017 Apr;42(4):312-325
pubmed: 28185716
J Physiol. 2002 Aug 1;542(Pt 3):735-41
pubmed: 12154175
J Pharm Pharmacol. 2016 Jun;68(6):729-41
pubmed: 26989862
Annu Rev Biochem. 2003;72:77-109
pubmed: 14527321
Pharmazie. 2019 Dec 1;74(12):737-739
pubmed: 31907113
Methods Mol Biol. 2012;837:231-9
pubmed: 22215552
Essays Biochem. 2010;47:53-67
pubmed: 20533900
N Engl J Med. 2008 Oct 9;359(15):1577-89
pubmed: 18784090
Acta Pharm Sin B. 2020 Mar;10(3):475-487
pubmed: 32140393
Am J Physiol. 1994 Feb;266(2 Pt 2):H829-39
pubmed: 8141383
Aging Cell. 2018 Aug;17(4):e12765
pubmed: 29659168
PLoS One. 2010 Jan 18;5(1):e8758
pubmed: 20090912
Elife. 2017 Oct 24;6:
pubmed: 29035201
Dev Cell. 2019 Mar 11;48(5):685-696.e5
pubmed: 30713071