Is SARS-CoV-2 seroconversion a risk factor for severe and acute psychiatric symptoms in children?


Journal

Neuropsychopharmacology reports
ISSN: 2574-173X
Titre abrégé: Neuropsychopharmacol Rep
Pays: United States
ID NLM: 101719700

Informations de publication

Date de publication:
06 2022
Historique:
revised: 19 01 2022
received: 22 12 2021
accepted: 20 01 2022
pubmed: 9 3 2022
medline: 25 6 2022
entrez: 8 3 2022
Statut: ppublish

Résumé

Since the beginning of the COVID pandemic, studies reported an increase in children's mental health issues and questioned the impact of SARS-CoV-2 on psychiatric symptoms. We compared COVID seroconversion in children hospitalized with acute, severe psychiatric symptoms (n = 52) with the sex- and age-matched control group (n = 52) living in the same low-income geographic area and sampled during the same time period. Contrary to our hypothesis, we observed less seroconverted children with psychiatric conditions 9.61% (95% CI, 3.59-21.80) vs 34.61% (95% CI, 22.33-49.16; χ This suggests a lower direct impact of SARS-CoV-2 compared with the impact of mitigation strategies on psychiatric symptom deterioration in children reported since early stages of the pandemic.

Identifiants

pubmed: 35257512
doi: 10.1002/npr2.12236
pmc: PMC9216372
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

218-220

Informations de copyright

© 2022 The Authors. Neuropsychopharmacology Reports published by John Wiley & Sons Australia, Ltd on behalf of The Japanese Society of Neuropsychopharmacology.

Références

J Neurol. 2020 Aug;267(8):2179-2184
pubmed: 32458193
Nature. 2021 Jul;595(7868):482-483
pubmed: 34262190
Anxiety Stress Coping. 2020 Sep;33(5):590-601
pubmed: 32436731
BMJ Open. 2021 Nov 23;11(11):e053201
pubmed: 34815286
Neuropsychopharmacol Rep. 2022 Jun;42(2):218-220
pubmed: 35257512
JAMA Netw Open. 2021 Oct 1;4(10):e2128611
pubmed: 34618041
Lancet Child Adolesc Health. 2021 Sep;5(9):631-641
pubmed: 34273304

Auteurs

Anaël Ayrolles (A)

Child and Adolescent Psychiatry Department, Assistance Publique-Hôpitaux de Paris, Robert Debré Hospital, Paris, France.
Paris University, Paris, France.

Pierre Ellul (P)

Child and Adolescent Psychiatry Department, Assistance Publique-Hôpitaux de Paris, Robert Debré Hospital, Paris, France.
Paris University, Paris, France.

Vincent Trebossen (V)

Child and Adolescent Psychiatry Department, Assistance Publique-Hôpitaux de Paris, Robert Debré Hospital, Paris, France.
Paris University, Paris, France.

Nadira Houhou-Fidouh (N)

Virology Department, Assistance Publique-Hôpitaux de Paris, Bichat Hospital, Paris, France.

Stephane Bonacorsi (S)

Paris University, Paris, France.
Microbiology Department, Assistance Publique-Hôpitaux de Paris, Robert Debré Hospital, Paris, France.

Diane Descamps (D)

Paris University, Paris, France.
Virology Department, Assistance Publique-Hôpitaux de Paris, Bichat Hospital, Paris, France.

Richard Delorme (R)

Child and Adolescent Psychiatry Department, Assistance Publique-Hôpitaux de Paris, Robert Debré Hospital, Paris, France.
Paris University, Paris, France.
Cognitive and Genetic Functions, Institute Pasteur, Paris, France.

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