Three-vessel spontaneous coronary artery dissection in a patient with hyperhomocysteinemia.

Hyperhomocysteimemia Methylenetetrahydrofolate reductase Spontaneous coronary artery dissection

Journal

Journal of cardiology cases
ISSN: 1878-5409
Titre abrégé: J Cardiol Cases
Pays: Japan
ID NLM: 101549579

Informations de publication

Date de publication:
Mar 2022
Historique:
received: 22 04 2021
revised: 25 08 2021
accepted: 05 09 2021
entrez: 9 3 2022
pubmed: 10 3 2022
medline: 10 3 2022
Statut: epublish

Résumé

Increased homocysteine has been related to the occurrence of dissections in the coronary circulation, aorta, and cervical arteries. Spontaneous coronary artery dissection (SCAD) is a relatively rare phenomenon, and data on the long-term follow-up of patients with SCAD are extremely limited. Herein, we describe a case of a young male patient with 3-vessel SCAD (presence of radiolucent linear defects indicating the presence of dissections in all three major coronary arteries) who was found to have hyperhomocysteinemia and a concurrent methylenetetrahydrofolate reductase prothrombotic mutation. Despite the presence of multi-vessel SCAD, the patient had clinically stable coronary artery disease for a long period. <

Identifiants

pubmed: 35261707
doi: 10.1016/j.jccase.2021.09.003
pii: S1878-5409(21)00149-3
pmc: PMC8888715
doi:

Types de publication

Case Reports

Langues

eng

Pagination

182-184

Informations de copyright

© 2021 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

The authors declare that there is no conflict of interest.

Références

Am J Cardiol. 1989 Sep 1;64(8):471-4
pubmed: 2773790
J Cardiol Cases. 2012 Mar 06;5(2):e69-e72
pubmed: 30532907
Perfusion. 2013 Sep;28(5):457-8
pubmed: 23690315
Nutr Metab Cardiovasc Dis. 2017 Feb;27(2):168-175
pubmed: 27773468
Med Hypotheses. 2005;64(5):1007-10
pubmed: 15780501
Circulation. 2012 Jul 31;126(5):579-88
pubmed: 22800851
Int J Cardiol. 2004 Sep;96(3):341-5
pubmed: 15301885
Am J Cardiol. 2017 Sep 1;120(5):740-746
pubmed: 28689750
Cerebrovasc Dis. 2009;27(3):241-6
pubmed: 19176957
JACC Cardiovasc Interv. 2012 Oct;5(10):1062-70
pubmed: 23078737

Auteurs

Christos S Katsouras (CS)

2nd Department of Cardiology, University Hospital of Ioannina, Ioannina, Greece.

Michail I Papafaklis (MI)

2nd Department of Cardiology, University Hospital of Ioannina, Ioannina, Greece.

Lampros Lakkas (L)

2nd Department of Cardiology, University Hospital of Ioannina, Ioannina, Greece.

Aidonis Rammos (A)

2nd Department of Cardiology, University Hospital of Ioannina, Ioannina, Greece.

Lampros K Michalis (LK)

2nd Department of Cardiology, University Hospital of Ioannina, Ioannina, Greece.

Classifications MeSH