Prenatal quantification of human foetal lung and liver elasticities between 24 and 39 weeks of gestation using 2D shear wave elastography.
Dispersion
Elasticity
Foetal liver
Foetal lung
Shear wave elastography
Journal
European radiology
ISSN: 1432-1084
Titre abrégé: Eur Radiol
Pays: Germany
ID NLM: 9114774
Informations de publication
Date de publication:
Aug 2022
Aug 2022
Historique:
received:
26
09
2021
accepted:
14
02
2022
revised:
13
02
2022
pubmed:
11
3
2022
medline:
16
7
2022
entrez:
10
3
2022
Statut:
ppublish
Résumé
To quantify and model normal foetal lung and liver elasticities between 24 and 39 weeks of gestation (WG) using two-dimensional shear wave elastography (2D-SWE). To assess the impact of the distance between the probe and the target organ on the estimation of elasticity values. Measurements of normal foetal lungs and liver elasticity were prospectively repeated monthly between 24 and 39 WG in 72 foetuses using 2D-SWE. Elasticity was quantified in the proximal lung and in the region inside the hepatic portal sinus. The distance between the probe and the target organ was recorded. Trajectories representing foetal lung and liver maturation from at least 3 measurements over time were modelled. The average elasticity for the lung and liver was significantly different from 24 WG to 36 WG (p < 0.01). Liver elasticity increased during gestation (3.86 kPa at 24 WG versus 4.45 kPa at 39 WG). From 24 WG to 32 WG, lung elasticity gradually increased (4.12kPa at 24 WG, 4.91kPa at 28 WG, 5.03kPa at 32 WG, p < 0.002). After 32 WG, lung elasticity decreased to 4.54kPa at 36 WG and 3.94kPa at 39 WG. The dispersion of the average elasticity values was greater for the lung than for the liver (p < 0.0001). Variation in the elasticity values was less important for the liver than for the lung. The values were considered valid and repeatable except for a probe-lung distance above 8cm. Foetal lung and liver elasticities evolve differently through gestation. This could reflect the tissue maturation of both organs during gestation. clinicaltrials.gov identifier: NCT03834805 KEY POINTS: • Prenatal quantification of foetal lung elasticity using 2D shear wave elastography could be a new prenatal parameter for exploring foetal lung maturity. • Liver elasticity increased progressively from 24 weeks of gestation (WG) to 39 WG, while lung elasticity increased first between 24 and 32 WG and then decreased after 32 WG. • The values of elasticity are considered valid and repeatable except for a probe-lung distance above 8cm.
Identifiants
pubmed: 35267093
doi: 10.1007/s00330-022-08654-1
pii: 10.1007/s00330-022-08654-1
pmc: PMC9279217
doi:
Banques de données
ClinicalTrials.gov
['NCT03834805']
Types de publication
Clinical Trial
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
5559-5567Informations de copyright
© 2022. The Author(s).
Références
Balestrini JL, Niklason LE (2015) Extracellular matrix as a driver for lung regeneration. Ann Biomed Eng 43:568–576
doi: 10.1007/s10439-014-1167-5
pubmed: 25344351
Suki B, Stamenovic D, Hubmayr R (2011) Lung Parenchymal Mechanics. Compr Physiol 1:1317–1351
doi: 10.1002/cphy.c100033
pubmed: 23733644
Torday JS, Sanchez-Esteban J, Rubin LP (1998) Paracrine mediators of mechanotransduction in lung development. Am J Med Sci 316:205–208
pubmed: 9749564
Fung YC (1975) Does the surface tension make the lung inherently unstable? Circ Res 37:497–502
doi: 10.1161/01.RES.37.4.497
pubmed: 1182941
Gennisson J-L, Deffieux T, Fink M, Tanter M (2013) Ultrasound elastography: principles and techniques. Diagn Interv Imaging 94:487–495
doi: 10.1016/j.diii.2013.01.022
pubmed: 23619292
Bercoff J, Tanter M, Fink M (2004) Supersonic shear imaging: a new technique for soft tissue elasticity mapping. IEEE Trans Ultrason Ferroelectr Freq Control 51:396–409
doi: 10.1109/TUFFC.2004.1295425
pubmed: 15139541
Carlson LC, Feltovich H, Palmeri ML, Dahl JJ, Munoz del Rio A, Hall TJ (2014) Estimation of shear wave speed in the human uterine cervix. Ultrasound Obstet Gynecol 43:452–458
doi: 10.1002/uog.12555
pubmed: 23836486
Alison M, Biran V, Tanase A et al (2015) Quantitative shear-wave elastography of the liver in preterm neonates with intra-uterine growth restriction. PLoS One 10:e0143220
doi: 10.1371/journal.pone.0143220
pubmed: 26580807
Abeysekera JM, Ma M, Pesteie M et al (2017) SWAVE imaging of placental elasticity and viscosity: proof of concept. Ultrasound Med Biol 43:1112–1124
doi: 10.1016/j.ultrasmedbio.2017.01.014
pubmed: 28392000
Alici Davutoglu E, Ariöz Habibi H, Ozel A, Yuksel MA, Adaletli I, Madazlı R (2017) The role of shear wave elastography in the assessment of placenta previa-accreta. J Matern Fetal Neonatal Med 31(12):1660–1662
doi: 10.1080/14767058.2017.1322059
pubmed: 28486823
Arioz Habibi H, Alici Davutoglu E, Kandemirli SG et al (2017) In vivo assessment of placental elasticity in intrauterine growth restriction by shear-wave elastography. Eur J Radiol 97:16–20
doi: 10.1016/j.ejrad.2017.10.007
pubmed: 29153362
Quarello E, Lacoste R, Mancini J, Melot-Dusseau S, Gorincour G (2016) ShearWave elastography of fetal lungs in pregnant baboons. Diagn Interv Imaging 97:605–610
doi: 10.1016/j.diii.2015.11.019
pubmed: 27085721
Quarello E, Lacoste R, Mancini J, Melot-Dusseau S, Gorincour G (2015) Feasibility and reproducibility of ShearWave(TM) elastography of fetal baboon organs. Prenat Diagn 35(11):1112–1116
doi: 10.1002/pd.4655
pubmed: 26194174
Mottet N, Cochet C, Vidal C et al (2020) Feasibility of two-dimensional ultrasound shear wave elastography of human fetal lungs and liver: a pilot study. Diagn Interv Imaging 101:69–78
doi: 10.1016/j.diii.2019.08.002
pubmed: 31447393
Beck APA, Araujo Júnior E, Leslie ATFS, Camano L, Moron AF (2015) Assessment of fetal lung maturity by ultrasound: objective study using gray-scale histogram. J Matern Fetal Neonatal Med 28:617–622
doi: 10.3109/14767058.2014.927862
pubmed: 24857165
Gorincour G, Bach-Segura P, Ferry-Juquin M et al (2009) Lung signal on fetal MRI: normal values and usefulness for congenital diaphragmatic hernia. J Radiol 90:53–58
doi: 10.1016/S0221-0363(09)70078-2
pubmed: 19182714
Moshiri M, Mannelli L, Richardson ML, Bhargava P, Dubinsky TJ (2013) Fetal lung maturity assessment with MRI fetal lung-to-liver signal-intensity ratio. AJR Am J Roentgenol 201:1386–1390
doi: 10.2214/AJR.12.9679
pubmed: 24261381
Palacio M, Bonet-Carne E, Cobo T et al (2017) Prediction of neonatal respiratory morbidity by quantitative ultrasound lung texture analysis: a multicenter study. Am J Obstet Gynecol 217:196.e1–196.e14
doi: 10.1016/j.ajog.2017.03.016
Donda K, Vijayakanthi N, Dapaah-Siakwan F, Bhatt P, Rastogi D, Rastogi S (2019) Trends in epidemiology and outcomes of respiratory distress syndrome in the United States. Pediatr Pulmonol 54:405–414
doi: 10.1002/ppul.24241
pubmed: 30663263
Foncea CG, Popescu A, Lupusoru R et al (2020) Comparative study between pSWE and 2D-SWE techniques integrated in the same ultrasound machine, with Transient Elastography as the reference method. Med Ultrason 22:13–19
doi: 10.11152/mu-2179
pubmed: 32096782
Kim DW, Suh CH, Kim KW, Pyo J, Park C, Jung SC (2019) Technical performance of two-dimensional shear wave elastography for measuring liver stiffness: a systematic review and meta-analysis. Korean J Radiol 20:880–893
doi: 10.3348/kjr.2018.0812
pubmed: 31132814
Carlsen JF, Pedersen MR, Ewertsen C et al (2015) A comparative study of strain and shear-wave elastography in an elasticity phantom. AJR Am J Roentgenol 204:W236–W242
doi: 10.2214/AJR.14.13076
pubmed: 25714307
Carstensen EL, Parker KJ, Lerner RM (2008) Elastography in the management of liver disease. Ultrasound Med Biol 34:1535–1546
doi: 10.1016/j.ultrasmedbio.2008.03.002
pubmed: 18485568
Barry CT, Mills B, Hah Z et al (2012) Shear wave dispersion measures liver steatosis. Ultrasound Med Biol 38(2):175–182
doi: 10.1016/j.ultrasmedbio.2011.10.019
pubmed: 22178165
Silva PDA, Uscategui RAR, Santos VJC et al (2019) Acoustic radiation force impulse (ARFI) elastography to asses maternal and foetal structures in pregnant ewes. Reprod Domest Anim 54:498–505
doi: 10.1111/rda.13384
pubmed: 30489657
Issaoui M, Debost-Legrand A, Skerl K et al (2018) Shear wave elastography safety in fetus: A quantitative health risk assessment. Diagn Interv Imaging 99(9):519–524
doi: 10.1016/j.diii.2018.04.013
pubmed: 29934239
Sugitani M, Fujita Y, Yumoto Y et al (2013) A new method for measurement of placental elasticity: acoustic radiation force impulse imaging. Placenta 34:1009–1013
doi: 10.1016/j.placenta.2013.08.014
pubmed: 24075540
Issaoui M, Miloro P, Balandraud X et al (2020) Temperature elevation in an instrumented phantom insonated by B-mode imaging, pulse Doppler and shear wave elastography. Ultrasound Med Biol 46:3317–3326
doi: 10.1016/j.ultrasmedbio.2020.08.021
pubmed: 32962891
Massó P, Melchor J, Rus G, Molina FS (2020) A preliminary study on the safety of elastography during pregnancy: Hypoacusia, anthropometry, and Apgar score in newborns. Diagnostics (Basel) 18 10(11):967
doi: 10.3390/diagnostics10110967
Massó P, Rus G, Molina F (2017) On the safety of elastography in fetal medicine: a preliminary study of hypoacusia. Ultrasound Obstet Gynecol 50(5):660–661
doi: 10.1002/uog.17429
pubmed: 28150442
Aubry S, Risson J-R, Kastler A et al (2013) Biomechanical properties of the calcaneal tendon in vivo assessed by transient shear wave elastography. Skelet Radiol 42:1143–1150
doi: 10.1007/s00256-013-1649-9
Shin HJ, Kim M-J, Kim HY, Roh YH, Lee M-J (2016) Comparison of shear wave velocities on ultrasound elastography between different machines, transducers, and acquisition depths: A phantom study. Eur Radiol 26:3361–3367
doi: 10.1007/s00330-016-4212-y
pubmed: 26815368
Zhao H, Song P, Urban MW et al (2011) Bias observed in time-of-flight shear wave speed measurements using radiation force of a focused ultrasound beam. Ultrasound Med Biol 37:1884–1892
doi: 10.1016/j.ultrasmedbio.2011.07.012
pubmed: 21924817
Dhyani M, Xiang F, Li Q et al (2018) Ultrasound shear wave elastography: Variations of liver fibrosis assessment as a function of depth, force and distance from central axis of the transducer with a comparison of different systems. Ultrasound Med Biol 44:2209–2222
doi: 10.1016/j.ultrasmedbio.2018.07.003
pubmed: 30143339
Bouchet P, Gennisson J-L, Podda A, Alilet M, Carrié M, Aubry S (2020) Artifacts and technical restrictions in 2D shear wave elastography. Ultraschall Med 41:267–277
doi: 10.1055/a-0805-1099
pubmed: 30577047