A Complex In Vitro Degradation Study on Polydioxanone Biliary Stents during a Clinically Relevant Period with the Focus on Raman Spectroscopy Validation.
Raman spectroscopy
Young’s modulus
biliary stent
degradation
differential scanning calorimetry
polydioxanone
tensile strength
Journal
Polymers
ISSN: 2073-4360
Titre abrégé: Polymers (Basel)
Pays: Switzerland
ID NLM: 101545357
Informations de publication
Date de publication:
26 Feb 2022
26 Feb 2022
Historique:
received:
27
01
2022
revised:
18
02
2022
accepted:
23
02
2022
entrez:
10
3
2022
pubmed:
11
3
2022
medline:
11
3
2022
Statut:
epublish
Résumé
Biodegradable biliary stents are promising treatments for biliary benign stenoses. One of the materials considered for their production is polydioxanone (PPDX), which could exhibit a suitable degradation time for use in biodegradable stents. Proper material degradation characteristics, such as sufficient stiffness and disintegration resistance maintained for a clinically relevant period, are necessary to ensure stent safety and efficacy. The hydrolytic degradation of commercially available polydioxanone biliary stents (ELLA-CS, Hradec Králové, Czech Republic) in phosphate-buffered saline (PBS) was studied. During 9 weeks of degradation, structural, physical, and surface changes were monitored using Raman spectroscopy, differential scanning calorimetry, scanning electron microscopy, and tensile and torsion tests. It was found that the changes in mechanical properties are related to the increase in the ratio of amorphous to crystalline phase, the so-called amorphicity. Monitoring the amorphicity using Raman spectroscopy has proven to be an appropriate method to assess polydioxanone biliary stent degradation. At the 1732 cm
Identifiants
pubmed: 35267761
pii: polym14050938
doi: 10.3390/polym14050938
pmc: PMC8912347
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Ministry of Youth, Education and Sports of the Czech Republic
ID : LM2018103
Organisme : Ministry of Youth, Education and Sports of the Czech Republic
ID : PROGRES Q40-09
Organisme : Ministry of Youth, Education and Sports of the Czech Republic
ID : UHK 2215/2022-2023
Références
World J Gastrointest Endosc. 2013 Jul 16;5(7):332-9
pubmed: 23858377
Arq Bras Cir Dig. 2016 Apr-Jun;29(2):112-6
pubmed: 27438039
Curr Gastroenterol Rep. 2013 Aug;15(8):336
pubmed: 23857116
Int J Pediatr Otorhinolaryngol. 2020 Dec;139:110405
pubmed: 33017664
Endoscopy. 2013 Dec;45(12):997-1005
pubmed: 24288220
Eur Radiol. 2020 Aug;30(8):4486-4495
pubmed: 32221684
Polymers (Basel). 2011 Sep 1;3(3):1377-1397
pubmed: 22577513
Biomaterials. 1996 Jan;17(2):103-14
pubmed: 8624387
J Hepatobiliary Pancreat Sci. 2011 May;18(3):463-7
pubmed: 21170555
Biomacromolecules. 2004 Mar-Apr;5(2):358-70
pubmed: 15002995
Surg Endosc. 2017 Dec;31(12):5076-5082
pubmed: 28444492
Rev Esp Enferm Dig. 2017 Jul;109(7):510-515
pubmed: 28593785
Endoscopy. 2010;42 Suppl 2:E89-90
pubmed: 20195981
Endoscopy. 2012 Jul;44(7):649-54
pubmed: 22723182
J Biomed Mater Res. 1993 Feb;27(2):153-66
pubmed: 8436572
Singapore Med J. 2003 Dec;44(12):614-9
pubmed: 14770254
Endoscopy. 2018 Dec;50(12):1146-1155
pubmed: 29883979
J Surg Res. 1994 Apr;56(4):372-7
pubmed: 8152233
Molecules. 2021 Jun 24;26(13):
pubmed: 34202602
Gastrointest Endosc. 2012 Jul;76(1):84-92
pubmed: 22482918
Bioact Mater. 2021 Oct 11;11:140-153
pubmed: 34938919
J Thorac Cardiovasc Surg. 2012 Feb;143(2):437-44
pubmed: 21885070
Gastrointest Endosc. 2014 Nov;80(5):908-13
pubmed: 25070907
Gastrointest Endosc. 2010 Nov;72(5):927-34
pubmed: 21034894
Biomed Res Int. 2013;2013:137985
pubmed: 24089660
Endoscopy. 2011 Oct;43(10):911-7
pubmed: 21623562
Nanomaterials (Basel). 2019 Oct 31;9(11):
pubmed: 31683612
J Pediatr Gastroenterol Nutr. 2009 Aug;49(2):254-7
pubmed: 19561544
J Biomed Mater Res A. 2014 Apr;102(4):982-90
pubmed: 23625859
Cardiovasc Intervent Radiol. 2020 May;43(5):749-755
pubmed: 32133551
World J Gastroenterol. 2014 Mar 7;20(9):2212-7
pubmed: 24605020
PLoS One. 2020 Jul 8;15(7):e0235842
pubmed: 32639989
J Bronchology Interv Pulmonol. 2020 Jul;27(3):200-204
pubmed: 32101914
J Am Acad Orthop Surg. 2001 Sep-Oct;9(5):280-8
pubmed: 11575907
Biomaterials. 2021 Jan;266:120477
pubmed: 33120198
Gastroenterol Hepatol (N Y). 2012 Aug;8(8):526-34
pubmed: 23293566
Dig Dis Sci. 2013 Nov;58(11):3270-9
pubmed: 23861111
J Biomed Mater Res B Appl Biomater. 2005 Aug;74(2):792-9
pubmed: 15991233
Cardiovasc Intervent Radiol. 2011 Dec;34(6):1267-71
pubmed: 21213108
Biomaterials. 2002 Sep;23(17):3575-82
pubmed: 12109681
Eur Radiol. 2016 Nov;26(11):4057-4063
pubmed: 26943135
Materials (Basel). 2021 Sep 21;14(18):
pubmed: 34576686
Dig Endosc. 2017 Jan;29(1):118-121
pubmed: 27514703
Pediatr Pulmonol. 2016 Jun;51(6):607-12
pubmed: 26584412
Proc Natl Acad Sci U S A. 2018 Mar 13;115(11):2640-2645
pubmed: 29483243
Rev Esp Enferm Dig. 2018 Dec;110(12):826-829
pubmed: 30338691
Surg Gynecol Obstet. 1981 Oct;153(4):497-507
pubmed: 6792722
Circ Cardiovasc Interv. 2009 Jun;2(3):255-60
pubmed: 20031723
Eur J Gastroenterol Hepatol. 2018 Aug;30(8):813-818
pubmed: 29782386
BMC Pulm Med. 2015 Dec 21;15:164
pubmed: 26690793
Catheter Cardiovasc Interv. 2007 Feb 15;69(3):443-6
pubmed: 17295281