Sarcopenic Dysphagia, Malnutrition, and Oral Frailty in Elderly: A Comprehensive Review.
dysphagia
elderly
malnutrition
oral health
osteoporosis
sarcopenia
sarcopenic dysphagia
Journal
Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595
Informations de publication
Date de publication:
25 Feb 2022
25 Feb 2022
Historique:
received:
11
02
2022
revised:
23
02
2022
accepted:
24
02
2022
entrez:
10
3
2022
pubmed:
11
3
2022
medline:
15
3
2022
Statut:
epublish
Résumé
Frailty is a highly prevalent condition in the elderly that has been increasingly considered as a crucial public health issue, due to the strict correlation with a higher risk of fragility fractures, hospitalization, and mortality. Among the age-related diseases, sarcopenia and dysphagia are two common pathological conditions in frail older people and could coexist leading to dehydration and malnutrition in these subjects. "Sarcopenic dysphagia" is a complex condition characterized by deglutition impairment due to the loss of mass and strength of swallowing muscles and might be also related to poor oral health status. Moreover, the aging process is strictly related to poor oral health status due to direct impairment of the immune system and wound healing and physical and cognitive impairment might indirectly influence older people's ability to carry out adequate oral hygiene. Therefore, poor oral health might affect nutrient intake, leading to malnutrition and, consequently, to frailty. In this scenario, sarcopenia, dysphagia, and oral health are closely linked sharing common pathophysiological pathways, disabling sequelae, and frailty. Thus, the aim of the present comprehensive review is to describe the correlation among sarcopenic dysphagia, malnutrition, and oral frailty, characterizing their phenotypically overlapping features, to propose a comprehensive and effective management of elderly frail subjects.
Identifiants
pubmed: 35267957
pii: nu14050982
doi: 10.3390/nu14050982
pmc: PMC8912303
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Références
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008 Aug;106(2):235-41
pubmed: 18417382
Acta Odontol Scand. 2021 Dec 2;:1-13
pubmed: 34855562
J Biol Regul Homeost Agents. 2018 Jan-Feb;32(2 Suppl. 1):113-116
pubmed: 29460527
Odontology. 2009 Jul;97(2):76-83
pubmed: 19639449
Geriatr Nurs. 2002 Jul-Aug;23(4):189-99
pubmed: 12183742
Dysphagia. 2003 Spring;18(2):126-34
pubmed: 12825906
Gerodontology. 2002 Jul;19(1):17-24
pubmed: 12164234
J Frailty Aging. 2018;7(1):2-9
pubmed: 29412436
J Nutr Gerontol Geriatr. 2015;34(1):1-21
pubmed: 25803601
J Oral Rehabil. 2020 May;47(5):584-590
pubmed: 31976566
Cochrane Database Syst Rev. 2007 Jul 18;(3):CD003782
pubmed: 17636736
Compend Contin Educ Dent. 2016 May;37(5):306-311;quiz312
pubmed: 27213776
J Prosthodont Res. 2021 Jun 30;65(2):131-136
pubmed: 32938852
Clin Nutr. 2015 Jun;34(3):335-40
pubmed: 25799486
J Pain Symptom Manage. 2013 Aug;46(2):201-6
pubmed: 23159683
Heart Lung Circ. 2018 Nov;27(11):1327-1334
pubmed: 29903685
World J Orthop. 2021 Jul 18;12(7):456-466
pubmed: 34354934
Dysphagia. 2021 Jun;36(3):523-531
pubmed: 33620563
Arch Phys Med Rehabil. 2005 Aug;86(8):1516-20
pubmed: 16084801
Nutr Rev. 2020 Feb 1;78(2):175-188
pubmed: 31397482
Aging Clin Exp Res. 2019 Oct;31(10):1517-1524
pubmed: 30539540
Diabet Med. 2010 Nov;27(11):1280-3
pubmed: 20950386
Int J Environ Res Public Health. 2013 Dec 05;10(12):6799-819
pubmed: 24317386
Community Dent Health. 1999 Mar;16(1):12-7
pubmed: 10697349
Nutr Rev. 1998 Jan;56(1 Pt 2):S27-37
pubmed: 9481122
Clin Interv Aging. 2017 Jan 31;12:241-251
pubmed: 28203065
Nutrients. 2019 Nov 29;11(12):
pubmed: 31795351
Geriatr Gerontol Int. 2017 Jun;17(6):1031-1033
pubmed: 28635108
Aging Clin Exp Res. 2017 Feb;29(1):35-42
pubmed: 28181204
NeuroRehabilitation. 2021;48(1):49-57
pubmed: 33386822
J Am Geriatr Soc. 2018 Mar;66(3):609-613
pubmed: 29266168
Nutrients. 2021 Feb 11;13(2):
pubmed: 33670314
J Nutr Health Aging. 2020;24(9):1003-1010
pubmed: 33155629
Eur J Clin Nutr. 2005 Oct;59(10):1149-57
pubmed: 16015256
Am J Phys Med Rehabil. 2020 May;99(5):e64-e67
pubmed: 31058647
Aging Clin Exp Res. 2018 Jun;30(6):625-631
pubmed: 29488185
Otolaryngol Clin North Am. 2018 Aug;51(4):769-777
pubmed: 29779617
Clin Nutr. 2017 Aug;36(4):1089-1096
pubmed: 27426415
Eur J Phys Rehabil Med. 2021 Dec;57(6):900-911
pubmed: 33541045
Nutrients. 2019 Oct 23;11(11):
pubmed: 31652734
J Nutr Health Aging. 2006 Nov-Dec;10(6):456-63; discussion 463-5
pubmed: 17183418
Geriatr Gerontol Int. 2019 Feb;19(2):91-97
pubmed: 30628181
Aging Clin Exp Res. 2019 Jun;31(6):799-805
pubmed: 30671866
Eur J Phys Rehabil Med. 2018 Oct;54(5):676-682
pubmed: 28696084
Aging Clin Exp Res. 2020 Jun;32(6):1093-1099
pubmed: 31368089
Lancet. 2016 May 21;387(10033):2145-2154
pubmed: 26520231
J Frailty Sarcopenia Falls. 2018 Mar 01;3(1):1-7
pubmed: 32300688
Curr Phys Med Rehabil Rep. 2014 Dec 1;2(4):197-206
pubmed: 26484001
Dysphagia. 2015 Jun;30(3):321-7
pubmed: 25750039
Am J Clin Nutr. 1997 Aug;66(2):460S-463S
pubmed: 9250133
Community Dent Oral Epidemiol. 2014 Oct;42(5):441-50
pubmed: 25353039
J Periodontol. 2013 Apr;84(4 Suppl):S135-52
pubmed: 23631574
Support Care Cancer. 2020 Nov;28(11):5263-5270
pubmed: 32103357
J Frailty Aging. 2014;3(2):97-103
pubmed: 27049901
Nutr Clin Pract. 2021 Aug;36(4):828-832
pubmed: 34161626
JPEN J Parenter Enteral Nutr. 1998 May-Jun;22(3):156-66
pubmed: 9586794
J Family Med Prim Care. 2018 Nov-Dec;7(6):1429-1433
pubmed: 30613537
Aging Clin Exp Res. 2016 Aug;28(4):607-17
pubmed: 26589905
Gerodontology. 2004 Sep;21(3):155-60
pubmed: 15369018
Nutr Hosp. 2007 Jan-Feb;22(1):7-24
pubmed: 17260529
J Evid Based Complementary Altern Med. 2016 Jan;21(1):30-3
pubmed: 26137850
Best Pract Res Clin Endocrinol Metab. 2014 Dec;28(6):795-808
pubmed: 25432353
Eur J Phys Rehabil Med. 2021 Dec;57(6):940-947
pubmed: 33759440
Clin Nutr. 2018 Jun;37(3):824-830
pubmed: 28392164
J Nutr Health Aging. 2018;22(8):1003-1009
pubmed: 30272106
Turk Pediatri Ars. 2019 Sep 25;54(3):139-140
pubmed: 31619924
J Am Geriatr Soc. 1986 Mar;34(3):192-8
pubmed: 3950287
J Nutr Health Aging. 2016 Feb;20(2):185-91
pubmed: 26812515
Geriatr Gerontol Int. 2013 Jan;13(1):43-9
pubmed: 22530802
Clin Nutr. 2014 Apr;33(2):316-21
pubmed: 23773972
Community Dent Oral Epidemiol. 2005 Apr;33(2):81-92
pubmed: 15725170
Eur J Phys Rehabil Med. 2021 Feb;57(1):131-136
pubmed: 32594668
J Am Med Dir Assoc. 2018 Jun;19(6):516-522
pubmed: 29287693
Front Physiol. 2019 Jul 03;10:855
pubmed: 31333498
Dysphagia. 1992;7(2):86-101
pubmed: 1572231
J Am Geriatr Soc. 2015 Feb;63(2):375-8
pubmed: 25688608
Clin Nutr. 2016 Dec;35(6):1282-1290
pubmed: 27086194
Oral Dis. 2017 May;23(4):526-536
pubmed: 28120363
Nutrients. 2020 Oct 12;12(10):
pubmed: 33053651
J Clin Med. 2019 Jul 31;8(8):
pubmed: 31370168
J Prosthet Dent. 1983 Jun;49(6):825-31
pubmed: 6576137
Lancet. 2020 Jan 4;395(10217):75-88
pubmed: 31852605
Geriatr Gerontol Int. 2019 May;19(5):429-437
pubmed: 30864254
J Nutr Health Aging. 2019;23(3):256-265
pubmed: 30820514
Cent Eur J Immunol. 2021;46(2):264-269
pubmed: 34764797
Int J Environ Res Public Health. 2019 Nov 03;16(21):
pubmed: 31684165
Osteoporos Int. 2021 Dec 2;:
pubmed: 34854956
Nutrients. 2019 Aug 23;11(9):
pubmed: 31443594
J Rehabil Med. 2021 Jan 5;53(1):jrm00141
pubmed: 33284353
Front Nutr. 2021 Jun 24;8:684840
pubmed: 34249993
Nutrition. 1999 Jun;15(6):458-64
pubmed: 10378201
Ther Adv Chronic Dis. 2019 Jan 31;10:2040622318821622
pubmed: 30728931
Diagnostics (Basel). 2021 Nov 21;11(11):
pubmed: 34829505
Exp Biol Med (Maywood). 2014 Nov;239(11):1524-30
pubmed: 24668555
Front Immunol. 2021 Jul 13;12:694217
pubmed: 34326845
Ann Otol Rhinol Laryngol. 2015 May;124(5):351-4
pubmed: 25358607
J Am Med Dir Assoc. 2013 Aug;14(8):542-59
pubmed: 23867520
Nutrients. 2021 Nov 12;13(11):
pubmed: 34836299
Support Care Cancer. 2010 Mar;18(3):395-8
pubmed: 19960207
Clin Interv Aging. 2012;7:287-98
pubmed: 22956864
J Clin Med. 2021 Oct 02;10(19):
pubmed: 34640596
Nutrients. 2020 Feb 22;12(2):
pubmed: 32098380
Nutr Diet. 2020 Feb;77(1):60-75
pubmed: 31157519
Front Physiol. 2017 Sep 22;8:676
pubmed: 28970804
J Gerontol Nurs. 2016 May 1;42(5):30-7
pubmed: 26716459
Clin Nutr. 2001 Apr;20(2):167-70
pubmed: 11327745
Cochrane Database Syst Rev. 2012 Feb 15;(2):CD003814
pubmed: 22336794
Am J Phys Med Rehabil. 2016 Jun;95(6):e84-9
pubmed: 26829095
Crit Rev Food Sci Nutr. 2011 Jan;51(1):67-90
pubmed: 21229419
J Acad Nutr Diet. 2016 Apr;116(4):573-7
pubmed: 26549542
Physiol Rev. 2019 Jan 1;99(1):427-511
pubmed: 30427277
J Am Geriatr Soc. 2011 Aug;59(8):1459-64
pubmed: 21797832
Int J Radiat Oncol Biol Phys. 2012 May 1;83(1):210-9
pubmed: 22014959
J Rheumatol. 2008 Aug;35(8):1489-94
pubmed: 18671323
Nutrients. 2019 Sep 24;11(10):
pubmed: 31554166
Nutrients. 2016 Jan 27;8(2):69
pubmed: 26828516
J Periodontol. 2007 Sep;78(9):1718-23
pubmed: 17760541
Geriatrics (Basel). 2018 Oct 12;3(4):
pubmed: 31011104
J Public Health Dent. 2000 Fall;60(4):308-12
pubmed: 11243052
Oral Dis. 2008 Mar;14(2):123-30
pubmed: 18208477
J Int Acad Periodontol. 2002 Jul;4(3):101-9
pubmed: 12670089
Eur Geriatr Med. 2018 Apr;9(2):141-148
pubmed: 34654260
Cochrane Database Syst Rev. 2018 Jun 08;6:CD012276
pubmed: 29883514
Dent Clin North Am. 2003 Apr;47(2):337-54
pubmed: 12699235
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Mar;103 Suppl:S57.e1-15
pubmed: 17379156
Open Access Maced J Med Sci. 2016 Sep 15;4(3):423-427
pubmed: 27703567
Age Ageing. 2010 Jul;39(4):412-23
pubmed: 20392703
Age Ageing. 2019 Jan 1;48(1):48-56
pubmed: 30052707
Aust Dent J. 2013 Jun;58(2):200-6
pubmed: 23713640
J Pharm Bioallied Sci. 2019 Feb;11(Suppl 1):S1-S12
pubmed: 30923424
Semin Hematol. 2008 Oct;45(4):225-34
pubmed: 18809092
Ann Acad Med Singap. 2001 Mar;30(2):148-54
pubmed: 11379412
Cochrane Database Syst Rev. 2015 Apr 17;(4):CD004622
pubmed: 25884249
Br J Nutr. 2006 Feb;95(2):325-30
pubmed: 16469149
Am J Phys Med Rehabil. 2021 Mar 1;100(3):280-287
pubmed: 33595941
Community Dent Oral Epidemiol. 1997 Jun;25(3):211-6
pubmed: 9192149
Age Ageing. 2014 Jan;43(1):132-7
pubmed: 24190874
J Prosthet Dent. 2001 Feb;85(2):141-7
pubmed: 11208203
Med Oral Patol Oral Cir Bucal. 2017 Nov 1;22(6):e708-e715
pubmed: 29053651
J Am Coll Cardiol. 2020 Aug 18;76(7):828-840
pubmed: 32792081
Cochrane Database Syst Rev. 2019 Oct 3;10:ED000142
pubmed: 31643080
Clin Interv Aging. 2016 Oct 07;11:1403-1428
pubmed: 27785002
Periodontol 2000. 2018 Oct;78(1):129-153
pubmed: 30198127
Aging Clin Exp Res. 2020 Oct;32(10):2073-2079
pubmed: 31673992
J Am Geriatr Soc. 2009 Jun;57(6):1073-9
pubmed: 19460090
Nutr Rev. 2006 Sep;64(9):410-21
pubmed: 17002237
J Am Geriatr Soc. 2012 Sep;60(9):1785-6
pubmed: 22985156
Arch Phys Med Rehabil. 2020 Sep;101(9):1662-1664
pubmed: 32534801
J Am Dent Assoc. 1996 Apr;127(4):459-67
pubmed: 8655866
J Nutr Health Aging. 2009 Nov;13(9):782-8
pubmed: 19812868
N Engl J Med. 2014 Oct 30;371(18):1673-84
pubmed: 25271389
BMC Geriatr. 2018 Mar 8;18(1):67
pubmed: 29519234
Dysphagia. 2021 Feb;36(1):33-40
pubmed: 32140906
Lancet. 2019 Oct 12;394(10206):1365-1375
pubmed: 31609228
Aging Clin Exp Res. 2018 Jan;30(1):77-80
pubmed: 28391586
J Periodontol. 2006 Sep;77(9):1465-82
pubmed: 16945022
Community Dent Oral Epidemiol. 2009 Feb;37(1):1-8
pubmed: 19046331
Arch Otolaryngol Head Neck Surg. 2007 Jun;133(6):564-71
pubmed: 17576907
Ann Otol Rhinol Laryngol. 2008 Dec;117(12):919-24
pubmed: 19140539
J Prosthodont Res. 2021 Jul 15;:
pubmed: 34261845
Implant Dent. 2017 Feb;26(1):54-58
pubmed: 27749520
J Nutr Health Aging. 2002;6(2):147-53
pubmed: 12166371
Curr Opin Clin Nutr Metab Care. 2022 Jan 1;25(1):29-36
pubmed: 34456248
J Investig Clin Dent. 2016 Feb;7(1):5-12
pubmed: 25175324
Eur J Intern Med. 2018 Oct;56:1-2
pubmed: 30253892
JAMA. 1997 May 7;277(17):1380-6
pubmed: 9134944
J Dent. 1999 Aug;27(6):443-8
pubmed: 10399411
Endocr Metab Immune Disord Drug Targets. 2019;19(8):1100-1115
pubmed: 31142256
Dysphagia. 2019 Oct;34(5):692-697
pubmed: 30612233
Nutrients. 2020 May 10;12(5):
pubmed: 32397658
Nutrition. 1999 Feb;15(2):116-22
pubmed: 9990575
Dysphagia. 2000 Winter;15(1):31-8
pubmed: 10594256
Nutrients. 2021 Jul 05;13(7):
pubmed: 34371823
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004 Jan;97(1):28-46
pubmed: 14716254
Aging Clin Exp Res. 2021 Dec;33(12):3205-3213
pubmed: 33904143
J Clin Periodontol. 2017 Mar;44 Suppl 18:S153-S177
pubmed: 28266110
Clin Nutr. 2018 Feb;37(1):204-207
pubmed: 28017450
Calcif Tissue Int. 2019 Jul;105(1):1-14
pubmed: 30972475
J Nutr Health Aging. 2014 Jan;18(1):34-8
pubmed: 24402386
J Am Geriatr Soc. 2015 Jan;63(1):151-7
pubmed: 25537919
Nutrition. 2009 Jul-Aug;25(7-8):717-22
pubmed: 19539173
Gerodontology. 2017 Jun;34(2):151-163
pubmed: 28168759
Clin Interv Aging. 2016 Feb 23;11:189-208
pubmed: 26966356
Dysphagia. 2020 Apr;35(2):369-377
pubmed: 31327077
Oral Surg Oral Med Oral Pathol Oral Radiol. 2015 Aug;120(2):185-206
pubmed: 25861957
J Prosthet Dent. 2001 Feb;85(2):162-9
pubmed: 11208206
J Nutr Health Aging. 2018;22(3):407-419
pubmed: 29484355
Nutrients. 2021 Aug 12;13(8):
pubmed: 34444924
Oral Surg Oral Med Oral Pathol Oral Radiol. 2012 Jul;114(1):52-60
pubmed: 22727092
Eur J Phys Rehabil Med. 2020 Feb;56(1):58-67
pubmed: 30916916
Clin Nutr. 2003 Jun;22(3):321-36
pubmed: 12765673
J Dent Res. 2013 Jul;92(7):592-7
pubmed: 23720570
Arch Phys Med Rehabil. 2018 May;99(5):934-944
pubmed: 29428348
Arch Phys Med Rehabil. 2010 May;91(5):743-9
pubmed: 20434612
CMAJ. 2004 Aug 3;171(3):251-9
pubmed: 15289425
Nutrition. 2017 Mar;35:128-131
pubmed: 28241980
J Clin Periodontol. 2021 Nov 10;:
pubmed: 34761413
Aging Clin Exp Res. 2019 Jan;31(1):85-94
pubmed: 29663160
Nutrition. 2018 Nov;55-56:104-110
pubmed: 29980089
Dysphagia. 2017 Apr;32(2):241-249
pubmed: 27687521
Gerodontology. 2016 Jun;33(2):161-8
pubmed: 24612262
Arch Gerontol Geriatr. 2009 Jul-Aug;49(1):32-4
pubmed: 18814924
Afr Health Sci. 2017 Mar;17(1):133-137
pubmed: 29026386
Gerodontology. 2002 Dec;19(2):95-101
pubmed: 12542218
J Gerontol A Biol Sci Med Sci. 2017 Sep 01;72(9):1290-1294
pubmed: 27707804
Clin Interv Aging. 2019 Mar 22;14:601-608
pubmed: 30962680
Bone. 2015 Nov;80:79-88
pubmed: 26453498
Am J Clin Nutr. 2005 Nov;82(5):1074-81
pubmed: 16280441
Risk Manag Healthc Policy. 2019 Feb 14;12:23-30
pubmed: 30858741
Curr Pharm Des. 2017;23(41):6256-6263
pubmed: 28552067
Arch Phys Med Rehabil. 2012 Jul;93(7):1173-8
pubmed: 22365489
Top Stroke Rehabil. 2020 Apr;27(3):208-214
pubmed: 31714187
J Clin Periodontol. 2021 Mar;48(3):336-347
pubmed: 33179280
J Periodontol. 2018 Jun;89 Suppl 1:S74-S84
pubmed: 29926944
Clin Nutr. 2018 Aug;37(4):1306-1312
pubmed: 28633943
Clin Nutr. 2019 Feb;38(1):10-47
pubmed: 30005900
J Prosthet Dent. 2002 Jun;87(6):667-73
pubmed: 12131890
Curr Med Res Opin. 2017 Dec;33(12):2195-2200
pubmed: 28699803
J Prosthodont Res. 2015 Jan;59(1):6-19
pubmed: 25498205
J Clin Periodontol. 2017 Mar;44 Suppl 18:S145-S152
pubmed: 28266118
J Gerontol A Biol Sci Med Sci. 2002 May;57(5):M326-32
pubmed: 11983728
Dysphagia. 2017 Feb;32(1):78-82
pubmed: 27571768
BMC Oral Health. 2013 Nov 01;13:61
pubmed: 24175989
Maturitas. 2020 Sep;139:6-11
pubmed: 32747042
J Am Geriatr Soc. 2016 Apr;64(4):739-51
pubmed: 27037761
Aging Clin Exp Res. 2017 Feb;29(1):43-48
pubmed: 28155181
J Am Med Dir Assoc. 2017 Jul 1;18(7):635.e1-635.e7
pubmed: 28363443
J Appl Oral Sci. 2020;28:e20190489
pubmed: 32401939
Biomed Res Int. 2017;2017:2672435
pubmed: 28421192
Eur Geriatr Med. 2020 Apr;11(2):195-207
pubmed: 32297199
Cochrane Database Syst Rev. 2018 Jan 01;1:CD009376
pubmed: 29291254
J Clin Periodontol. 2011 Mar;38 Suppl 11:3-6
pubmed: 21323698
J Am Dent Assoc. 2014 Aug;145(8):867-73
pubmed: 25082939
Prog Rehabil Med. 2018 Nov 20;3:20180019
pubmed: 32789244
J Gerontol A Biol Sci Med Sci. 2013 Jul;68(7):853-60
pubmed: 23112114
J Nutr Health Aging. 2019;23(1):84-88
pubmed: 30569074
Dysphagia. 2017 Apr;32(2):293-314
pubmed: 27913916
J Am Geriatr Soc. 2003 Sep;51(9):1237-43
pubmed: 12919235
Best Pract Res Clin Endocrinol Metab. 2018 Oct;32(5):739-757
pubmed: 30449552