Nonsurgical Periodontal Treatment Options and Their Impact on Subgingival Microbiota.
Eubacterium nodatum
Porphyromonas gingivalis
Prevotella dentalis
full-mouth disinfection
full-mouth disinfection with adjuvant erythritol air-polishing
full-mouth scaling
nonsurgical periodontal treatment
periodontitis stage III/IV
quadrant-wise debridement
subgingival microbiota
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
23 Feb 2022
23 Feb 2022
Historique:
received:
07
02
2022
revised:
18
02
2022
accepted:
21
02
2022
entrez:
10
3
2022
pubmed:
11
3
2022
medline:
11
3
2022
Statut:
epublish
Résumé
Different periodontal treatment methods (quadrant-wise debridement, scaling and root planing (Q-SRP), full-mouth scaling (FMS), full-mouth disinfection (FMD), and FMD with adjuvant erythritol air-polishing (FMDAP)) were applied in periodontitis patients (stage III/IV). The study objective (substudy of ClinicalTrials.gov Identifier: NCT03509233) was to compare the impact of treatments on subgingival colonization. Forty patients were randomized to the treatment groups. Periodontal parameters and subgingival colonization were evaluated at baseline and 3 and 6 months after treatment. Positive changes in clinical parameters were recorded in every treatment group during the 3-month follow-up period, but did not always continue. In three groups, specific bacteria decreased after 3 months; however, this was associated with a renewed increase after 6 months (FMS: The benefit of all clinical treatments measured after 3 months was associated with a decrease in pathogenic bacteria in the FMS, FMD, and FMDAP groups. However, after 6 months, we observed further improvement or some stagnation in clinical outcomes accompanied by deterioration of the microbiological profile. Investigating the subgingival microbiota might help appraise successful periodontal treatment and implement individualized therapy.
Sections du résumé
BACKGROUND
BACKGROUND
Different periodontal treatment methods (quadrant-wise debridement, scaling and root planing (Q-SRP), full-mouth scaling (FMS), full-mouth disinfection (FMD), and FMD with adjuvant erythritol air-polishing (FMDAP)) were applied in periodontitis patients (stage III/IV). The study objective (substudy of ClinicalTrials.gov Identifier: NCT03509233) was to compare the impact of treatments on subgingival colonization.
METHODS
METHODS
Forty patients were randomized to the treatment groups. Periodontal parameters and subgingival colonization were evaluated at baseline and 3 and 6 months after treatment.
RESULTS
RESULTS
Positive changes in clinical parameters were recorded in every treatment group during the 3-month follow-up period, but did not always continue. In three groups, specific bacteria decreased after 3 months; however, this was associated with a renewed increase after 6 months (FMS:
CONCLUSIONS
CONCLUSIONS
The benefit of all clinical treatments measured after 3 months was associated with a decrease in pathogenic bacteria in the FMS, FMD, and FMDAP groups. However, after 6 months, we observed further improvement or some stagnation in clinical outcomes accompanied by deterioration of the microbiological profile. Investigating the subgingival microbiota might help appraise successful periodontal treatment and implement individualized therapy.
Identifiants
pubmed: 35268280
pii: jcm11051187
doi: 10.3390/jcm11051187
pmc: PMC8911148
pii:
doi:
Banques de données
ClinicalTrials.gov
['NCT03509233']
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : E.M.S. Electro Medical Systems, Nyon/Switzerland
ID : no
Organisme : CP GABA GmbH, Hamburg/Germany
ID : no
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