The Splicing of the Mitochondrial Calcium Uniporter Genuine Activator MICU1 Is Driven by RBFOX2 Splicing Factor during Myogenic Differentiation.
alternative splicing
mitochondrial calcium homeostasis
myogenic differentiation
skeletal muscle
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
24 Feb 2022
24 Feb 2022
Historique:
received:
24
01
2022
revised:
17
02
2022
accepted:
22
02
2022
entrez:
10
3
2022
pubmed:
11
3
2022
medline:
9
4
2022
Statut:
epublish
Résumé
Alternative splicing, the process by which exons within a pre-mRNA transcript are differentially joined or skipped, is crucial in skeletal muscle since it is required both during myogenesis and in post-natal life to reprogram the transcripts of contractile proteins, metabolic enzymes, and transcription factors in functionally distinct muscle fiber types. The importance of such events is underlined by the numerosity of pathological conditions caused by alternative splicing aberrations. Importantly, many skeletal muscle Ca
Identifiants
pubmed: 35269658
pii: ijms23052517
doi: 10.3390/ijms23052517
pmc: PMC8909990
pii:
doi:
Substances chimiques
Calcium Channels
0
Calcium-Binding Proteins
0
Cation Transport Proteins
0
MICU1 protein, human
0
Mitochondrial Membrane Transport Proteins
0
RBFOX2 protein, human
0
RNA Splicing Factors
0
Repressor Proteins
0
mitochondrial calcium uniporter
0
Calcium
SY7Q814VUP
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Telethon Foundation
ID : GGP16026
Organisme : Italian Ministry of Health
ID : GR-2016-02362779
Organisme : Institute of Pediatric Research
ID : 19/10
Organisme : Cariparo Foundation
ID : 20/19
Références
Elife. 2020 Jul 15;9:
pubmed: 32667285
EMBO J. 2014 Mar 18;33(6):594-604
pubmed: 24514027
Differentiation. 2006 Mar;74(2-3):65-80
pubmed: 16533306
Cell. 1992 Feb 21;68(4):799-808
pubmed: 1310900
FASEB J. 1995 Jun;9(9):755-67
pubmed: 7601340
Science. 2003 Dec 12;302(5652):1978-80
pubmed: 14671308
Hum Mol Genet. 2006 Jul 1;15(13):2087-97
pubmed: 16717059
Elife. 2020 Aug 07;9:
pubmed: 32762847
Mol Cell Biol. 2007 Dec;27(24):8612-21
pubmed: 17923701
Nucleic Acids Res. 2010 Nov;38(21):7651-64
pubmed: 20634200
Genes Dev. 2008 Sep 15;22(18):2550-63
pubmed: 18794351
Ann Neurol. 2003 Dec;54(6):760-8
pubmed: 14681885
Proc Natl Acad Sci U S A. 2019 Dec 10;116(50):25203-25213
pubmed: 31754023
Nat Genet. 2008 Dec;40(12):1413-5
pubmed: 18978789
Mol Ther Nucleic Acids. 2017 Jun 16;7:90-100
pubmed: 28624228
Cell. 2016 Nov 17;167(5):1144
pubmed: 27863231
Nat Genet. 2002 Jan;30(1):29-30
pubmed: 11743582
J Cell Biol. 1981 Nov;91(2 Pt 1):497-504
pubmed: 6171575
Nat Biotechnol. 2010 May;28(5):511-5
pubmed: 20436464
Biostat Bioinforma Biomath. 2013 Aug;3(3):71-85
pubmed: 25558171
Nature. 2020 Jun;582(7810):129-133
pubmed: 32494073
Cell Calcium. 2021 Jan;93:102322
pubmed: 33264708
Cell Rep. 2015 Aug 18;12(7):1159-68
pubmed: 26257173
Neuron. 2020 Feb 19;105(4):678-687.e5
pubmed: 31862210
Science. 2012 Dec 21;338(6114):1593-9
pubmed: 23258891
Nat Biotechnol. 2004 May;22(5):535-46
pubmed: 15122293
Annu Rev Biophys Biophys Chem. 1987;16:535-59
pubmed: 2954560
EMBO J. 2020 Oct 1;39(19):e104285
pubmed: 32790952
Cell Rep. 2015 Mar 3;10(8):1269-79
pubmed: 25732818
J Biol Chem. 2004 Nov 26;279(48):50329-35
pubmed: 15381693
Dev Biol. 1992 Dec;154(2):273-83
pubmed: 1358730
Nat Rev Clin Oncol. 2020 Aug;17(8):457-474
pubmed: 32303702
Mol Cell. 2014 Aug 21;55(4):592-603
pubmed: 25087874
Cell Death Differ. 2019 Jan;26(1):179-195
pubmed: 29725115
Nature. 2011 Jun 19;476(7360):336-40
pubmed: 21685888
J Struct Biol. 2012 Jan;177(1):152-9
pubmed: 22100336
Hum Mol Genet. 2007 Dec 1;16(23):2834-43
pubmed: 17728322
FEBS Lett. 2018 Sep;592(17):2987-3006
pubmed: 29856907
Ann Neurol. 2011 Apr;69(4):681-90
pubmed: 21400563
Cell Rep. 2019 Apr 30;27(5):1541-1550.e5
pubmed: 31042479
J Biol Chem. 2007 Nov 30;282(48):35133-42
pubmed: 17916557
EMBO J. 2013 Aug 28;32(17):2362-76
pubmed: 23900286
Curr Opin Genet Dev. 2011 Aug;21(4):380-7
pubmed: 21514141
IUCrJ. 2020 Feb 27;7(Pt 2):355-365
pubmed: 32148862
Genes (Basel). 2018 Feb 19;9(2):
pubmed: 29463057
J Allergy Clin Immunol. 2004 Dec;114(6):1463-70
pubmed: 15577853
J Cell Sci. 2015 Feb 15;128(4):631-7
pubmed: 25609712
Biochem J. 1995 Jan 15;305 ( Pt 2):373-8
pubmed: 7832748
Nature. 2008 Nov 27;456(7221):470-6
pubmed: 18978772
Hum Mol Genet. 2012 Mar 15;21(6):1312-24
pubmed: 22140091
Hum Mol Genet. 2005 Aug 1;14(15):2189-200
pubmed: 15972723
Nat Genet. 2008 Dec;40(12):1416-25
pubmed: 18978788
Cell. 2009 Feb 20;136(4):777-93
pubmed: 19239895
Cell Rep. 2019 Jan 29;26(5):1203-1212.e4
pubmed: 30699349
Cell Rep. 2018 Jul 3;24(1):197-208
pubmed: 29972780
Nat Genet. 2002 Jan;30(1):13-9
pubmed: 11753382
EMBO J. 2000 Sep 1;19(17):4439-48
pubmed: 10970838
Orphanet J Rare Dis. 2021 Mar 12;16(1):129
pubmed: 33712050
Nat Rev Genet. 2014 Oct;15(10):689-701
pubmed: 25112293
Cell Death Dis. 2021 Nov 29;12(12):1115
pubmed: 34845191
Science. 2000 Sep 8;289(5485):1769-73
pubmed: 10976074
Mol Cell. 2016 Nov 17;64(4):760-773
pubmed: 27818145
Science. 2001 Aug 3;293(5531):864-7
pubmed: 11486088
Nucleic Acids Res. 2014 Jul;42(Web Server issue):W361-7
pubmed: 24829458
Mol Cell. 2014 Mar 6;53(5):726-37
pubmed: 24560927
J Biol Chem. 1987 Mar 15;262(8):3768-74
pubmed: 3029125
RNA. 2013 May;19(5):627-38
pubmed: 23525800
RNA. 2008 May;14(5):802-13
pubmed: 18369186
Cell. 1989 Mar 10;56(5):749-58
pubmed: 2924347
Methods Cell Biol. 2007;80:297-325
pubmed: 17445701
Nat Rev Mol Cell Biol. 2017 Nov;18(11):655-670
pubmed: 28951565
Science. 1992 Mar 6;255(5049):1256-8
pubmed: 1546326
Hum Mol Genet. 2015 Apr 15;24(8):2360-74
pubmed: 25575511
iScience. 2021 Jul 22;24(8):102895
pubmed: 34401674
Transcription. 2019 Feb;10(1):1-20
pubmed: 30556762
Science. 1992 Mar 6;255(5049):1253-5
pubmed: 1546325
Genes (Basel). 2020 Sep 22;11(9):
pubmed: 32971903
J Cachexia Sarcopenia Muscle. 2018 Feb;9(1):60-70
pubmed: 28984045
Curr Opin Neurobiol. 2019 Aug;57:26-31
pubmed: 30703685
Genes (Basel). 2013 Jun 04;4(2):275-92
pubmed: 24705164
Skelet Muscle. 2018 Mar 6;8(1):8
pubmed: 29510724
Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3546-3555
pubmed: 30755530