Identification of Surface Antigens That Define Human Pluripotent Stem Cell-Derived PRRX1+Limb-Bud-like Mesenchymal Cells.
PRRX1
human pluripotent stem cells
limb-bud mesenchyme
surface antigen
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
28 Feb 2022
28 Feb 2022
Historique:
received:
26
01
2022
revised:
24
02
2022
accepted:
27
02
2022
entrez:
10
3
2022
pubmed:
11
3
2022
medline:
9
4
2022
Statut:
epublish
Résumé
Stem cell-based therapies and experimental methods rely on efficient induction of human pluripotent stem cells (hPSCs). During limb development, the lateral plate mesoderm (LPM) produces limb-bud mesenchymal (LBM) cells that differentiate into osteochondroprogenitor cells and form cartilage tissues in the appendicular skeleton. Previously, we generated PRRX1-tdTomato reporter hPSCs to establish the protocol for inducing the hPSC-derived PRRX1
Identifiants
pubmed: 35269809
pii: ijms23052661
doi: 10.3390/ijms23052661
pmc: PMC8910499
pii:
doi:
Substances chimiques
Antigens, Surface
0
Homeodomain Proteins
0
Integrin alpha6
0
PRRX1 protein, human
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Japan Agency for Medical Research and Development
ID : 18bm0704024h0001
Organisme : Japan Agency for Medical Research and Development
ID : 20bm0404064h0001
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