Blood Thiol Redox State in Chronic Kidney Disease.
S-thiolated proteins
chronic kidney disease
end-stage renal disease
haemodialysis
peritoneal dialysis
protein thiolation index
protein thiols
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
05 Mar 2022
05 Mar 2022
Historique:
received:
31
12
2021
revised:
26
02
2022
accepted:
03
03
2022
entrez:
10
3
2022
pubmed:
11
3
2022
medline:
9
4
2022
Statut:
epublish
Résumé
Thiols (sulfhydryl groups) are effective antioxidants that can preserve the correct structure of proteins, and can protect cells and tissues from damage induced by oxidative stress. Abnormal levels of thiols have been measured in the blood of patients with moderate-to-severe chronic kidney disease (CKD) compared to healthy subjects, as well as in end-stage renal disease (ESRD) patients on haemodialysis or peritoneal dialysis. The levels of protein thiols (a measure of the endogenous antioxidant capacity inversely related to protein oxidation) and
Identifiants
pubmed: 35269995
pii: ijms23052853
doi: 10.3390/ijms23052853
pmc: PMC8911004
pii:
doi:
Substances chimiques
Antioxidants
0
Biomarkers
0
Proteins
0
Sulfhydryl Compounds
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
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