What Clinical Trials Are Needed for Treatment of Leiomyosarcoma?
Clinical trials
Leiomyosarcoma
NLMSF
Research
Treatment
Journal
Current treatment options in oncology
ISSN: 1534-6277
Titre abrégé: Curr Treat Options Oncol
Pays: United States
ID NLM: 100900946
Informations de publication
Date de publication:
03 2022
03 2022
Historique:
accepted:
26
07
2021
pubmed:
12
3
2022
medline:
6
4
2022
entrez:
11
3
2022
Statut:
ppublish
Résumé
Leiomyosarcoma is one of the most common subtypes of soft tissue sarcomas accounting for approximately 20% of sarcomas. As leiomyosarcoma patients frequently develop metastatic disease, effective systemic therapies are needed to improve clinical outcomes. The overall activity of the currently available conventional systemic therapies and the prognosis of patients with advanced and/or metastatic disease are poor. As such, the treatment of this patient population remains challenging. As a result, there is a clear unmet medical need, and designing and performing meaningful clinical studies are of utmost importance to improve the prognosis of this patient group. Therefore, the aim of this review is to briefly summarize state-of-the-art treatments for leiomyosarcoma patients and to describe trial characteristics needed for informative clinical studies.
Identifiants
pubmed: 35275323
doi: 10.1007/s11864-021-00928-y
pii: 10.1007/s11864-021-00928-y
pmc: PMC8930904
doi:
Types de publication
Journal Article
Review
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
439-449Informations de copyright
© 2022. The Author(s).
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