Caregiver-oncologist prognostic concordance, caregiving esteem, and caregiver outcomes.

Caregiver Depressive symptom Distress Prognostic understanding Quality of life

Journal

Journal of geriatric oncology
ISSN: 1879-4076
Titre abrégé: J Geriatr Oncol
Pays: Netherlands
ID NLM: 101534770

Informations de publication

Date de publication:
07 2022
Historique:
received: 01 06 2021
revised: 17 02 2022
accepted: 26 02 2022
pubmed: 13 3 2022
medline: 19 7 2022
entrez: 12 3 2022
Statut: ppublish

Résumé

Caregiver-oncologist concordance regarding the patient's prognosis is associated with worse caregiver outcomes (e.g., depressive symptoms), but mechanisms underpinning these associations are unclear. We explored whether caregiving esteem mediates these associations. At enrollment, caregivers and oncologists used a 5-point ordinal scale to estimate patient survival; identical responses were considered concordant. At 4-6 weeks, caregivers completed an assessment of the extent to which caregiving imparts self-esteem (Caregiver Reaction Assessment self-esteem subscale; range 0-5; higher score indicates greater esteem). They also completed Patient Health Questionnaire-2 (PHQ-2) for depressive symptoms, Distress Thermometer, and 12-Item Short Form Survey for quality of life (QoL). Mediation analysis with bootstrapping (PROCESS macro by Hayes) was used to estimate the extent to which caregiving mediated the effects of prognostic concordance on caregiver outcomes through caregiving esteem. Prognostic concordance occurred in 28% the caregiver-oncologist dyads; 85% of the discordance were due to caregivers estimating a longer patient's survival. At 4-6 weeks, mean caregiving esteem score was 4.4 (range 1.5-5.0). Lower caregiving esteem mediated the associations of concordance with higher PHQ-2 [indirect effect = 0.12; 95% Confidence Interval (CI) 0.03, 0.27], greater distress (indirect effect =0.25; 95% CI 0.08, 0.48), and poorer QoL (indirect effect = -1.50; 95% CI -3.06, -0.41). Caregiving esteem partially mediated 39%, 64%, and 48% of the associations between caregiver-oncologist concordance and PHQ-2, distress, and SF-12, respectively. Caregiver-oncologist concordance was associated with lower caregiving esteem. Lower caregiving esteem mediated the negative relationship between caregiver-oncologist concordance and caregiver outcomes.

Identifiants

pubmed: 35277372
pii: S1879-4068(22)00046-7
doi: 10.1016/j.jgo.2022.02.018
pmc: PMC9283218
mid: NIHMS1787452
pii:
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

828-833

Subventions

Organisme : NCI NIH HHS
ID : R00 CA237744
Pays : United States
Organisme : NIA NIH HHS
ID : R21 AG059206
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA168387
Pays : United States
Organisme : NCI NIH HHS
ID : K99 CA237744
Pays : United States
Organisme : NCI NIH HHS
ID : UG1 CA189961
Pays : United States
Organisme : NIA NIH HHS
ID : R33 AG059206
Pays : United States
Organisme : NIA NIH HHS
ID : K76 AG064394
Pays : United States
Organisme : NIA NIH HHS
ID : K24 AG056589
Pays : United States

Informations de copyright

Copyright © 2022 Elsevier Ltd. All rights reserved.

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Auteurs

Kah Poh Loh (KP)

Division of Hematology/Oncology, Department of Medicine, James P Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: kahpoh_loh@urmc.rochester.edu.

Erin Watson (E)

Division of Hematology/Oncology, Department of Medicine, James P Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: erin_watson@urmc.rochester.edu.

Eva Culakova (E)

Department of Surgery, Cancer Control, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: eva_culakova@urmc.rochester.edu.

Marie Flannery (M)

School of Nursing, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: marie_flannery@urmc.rochester.edu.

Michael Sohn (M)

Department of Biostatistics and Computational Biology, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: Michael_sohn@urmc.rochester.edu.

Huiwen Xu (H)

Preventive Medicine and Population Health University of Texas Medical Branch, Galveston, TX, USA. Electronic address: huiwen_xu@urmc.rochester.edu.

Sindhuja Kadambi (S)

Division of Hematology/Oncology, Department of Medicine, James P Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: sindhuja_kadambi@urmc.rochester.edu.

Allison Magnuson (A)

Division of Hematology/Oncology, Department of Medicine, James P Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: allison_magnuson@urmc.rochester.edu.

Colin McHugh (C)

Division of Hematology/Oncology, Department of Medicine, James P Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: colin_mchugh@urmc.rochester.edu.

Chandrika Sanapala (C)

Division of Hematology/Oncology, Department of Medicine, James P Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: chandrika_sanapala@urmc.rochester.edu.

Lee Kehoe (L)

Department of Surgery, Cancer Control, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: lee_kehoe@urmc.rochester.edu.

Victor G Vogel (VG)

Geisinger Cancer Institute NCORP, Danville, PA, USA. Electronic address: vgvogel@geisinger.edu.

Brian L Burnette (BL)

Cancer Research of Wisconsin and Northern Michigan (CROWN), Green Bay, WI, USA. Electronic address: brian.Burnette@gboncology.com.

Vincent Vinciguerra (V)

Northwell Health, New York, USA. Electronic address: vvincigu@northwell.edu.

Supriya G Mohile (SG)

Division of Hematology/Oncology, Department of Medicine, James P Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: supriya_mohile@urmc.rochester.edu.

Paul R Duberstein (PR)

Department of Health Behavior, Society, and Policy, Rutgers School of Public Health, Piscataway, NJ, USA. Electronic address: paul.duberstein@rutgers.edu.

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