First clinical experience with a novel, mobile cone-beam CT system for treatment quality assurance in brachytherapy.

Adaptive brachytherapy Gynecologic brachytherapy Image-guidance Mobile imaging On-site computed tomography imaging

Journal

Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]
ISSN: 1439-099X
Titre abrégé: Strahlenther Onkol
Pays: Germany
ID NLM: 8603469

Informations de publication

Date de publication:
06 2022
Historique:
received: 26 10 2021
accepted: 16 02 2022
pubmed: 13 3 2022
medline: 26 5 2022
entrez: 12 3 2022
Statut: ppublish

Résumé

On-site cone-beam computed tomography (CBCT) has gained in importance in adaptive brachytherapy during recent years. Besides treatment planning, there is increased need particularly for image-guidance during interventional procedures and for image-guided treatment quality assurance (QA). For this purpose, an innovative CBCT device was rolled out at our hospital as the first site worldwide. We present the first clinical images and experiences. The novel CBCT system is constructed of a 121 cm diameter ring gantry, and features a 43.2 × 43.2 cm With the presented device, treatment QA was feasible for the majority of patients. The CBCT scans of breast patients showed sufficient contrast between implanted catheters and tissue. For gynecologic patients, a distinct visualization of applicators was achieved in general. However, reasonable differentiations of organic soft tissues were not feasible. The CBCT system allowed basic treatment QA measures for breast and gynecologic patients. For image-guidance during interventional brachytherapy procedures, the current image quality is not adequate. Substantial performance enhancements are required for intraoperative image-guidance.

Sections du résumé

BACKGROUND AND PURPOSE
On-site cone-beam computed tomography (CBCT) has gained in importance in adaptive brachytherapy during recent years. Besides treatment planning, there is increased need particularly for image-guidance during interventional procedures and for image-guided treatment quality assurance (QA). For this purpose, an innovative CBCT device was rolled out at our hospital as the first site worldwide. We present the first clinical images and experiences.
MATERIALS AND METHODS
The novel CBCT system is constructed of a 121 cm diameter ring gantry, and features a 43.2 × 43.2 cm
RESULTS
With the presented device, treatment QA was feasible for the majority of patients. The CBCT scans of breast patients showed sufficient contrast between implanted catheters and tissue. For gynecologic patients, a distinct visualization of applicators was achieved in general. However, reasonable differentiations of organic soft tissues were not feasible.
CONCLUSION
The CBCT system allowed basic treatment QA measures for breast and gynecologic patients. For image-guidance during interventional brachytherapy procedures, the current image quality is not adequate. Substantial performance enhancements are required for intraoperative image-guidance.

Identifiants

pubmed: 35278094
doi: 10.1007/s00066-022-01912-7
pii: 10.1007/s00066-022-01912-7
pmc: PMC9165284
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

573-581

Informations de copyright

© 2022. The Author(s).

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Auteurs

Andre Karius (A)

Department of Radiation Oncology, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, Universitätsstr. 27, 91054, Erlangen, Germany. andre.karius@uk-erlangen.de.
Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), Erlangen, Germany. andre.karius@uk-erlangen.de.

Vratislav Strnad (V)

Department of Radiation Oncology, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, Universitätsstr. 27, 91054, Erlangen, Germany.
Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), Erlangen, Germany.

Michael Lotter (M)

Department of Radiation Oncology, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, Universitätsstr. 27, 91054, Erlangen, Germany.
Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), Erlangen, Germany.

Stephan Kreppner (S)

Department of Radiation Oncology, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, Universitätsstr. 27, 91054, Erlangen, Germany.
Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), Erlangen, Germany.

Christoph Bert (C)

Department of Radiation Oncology, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, Universitätsstr. 27, 91054, Erlangen, Germany.
Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), Erlangen, Germany.

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