Architecture- and Composition-Controlled Self-Assembly of Block Copolymers and Binary Mixtures With Crosslinkable Components: Chain Exchange Between Block Copolymer Nanoparticles.
block copolymers
crosslinking
polymer chain exchange
self-assembly
soft nanoparticles
Journal
Frontiers in chemistry
ISSN: 2296-2646
Titre abrégé: Front Chem
Pays: Switzerland
ID NLM: 101627988
Informations de publication
Date de publication:
2022
2022
Historique:
received:
11
12
2021
accepted:
24
01
2022
entrez:
14
3
2022
pubmed:
15
3
2022
medline:
15
3
2022
Statut:
epublish
Résumé
Chain exchange behaviors in self-assembled block copolymer (BCP) nanoparticles (NPs) at room temperature are investigated through observations of structural differences between parent and binary systems of BCP NPs with and without crosslinked domains. Pairs of linear diblock or triblock, and branched star-like polystyrene-poly(2-vinylpyridine) (PS-PVP) copolymers that self-assemble in a PVP-selective mixed solvent into BCP NPs with definite differences in size and self-assembled morphology are combined by diverse mixing protocols and at different crosslinking densities to reveal the impact of chain exchange between BCP NPs. Clear structural evolution is observed by dynamic light scattering and AFM and TEM imaging, especially in a blend of triblock + star copolymer BCP NPs. The changes are ascribed to the chain motion inherent in the dynamic equilibrium, which drives the system to a new structure, even at room temperature. Chemical crosslinking of PVP corona blocks suppresses chain exchange between the BCP NPs and freezes the nanostructures at a copolymer crosslinking density (CLD) of ∼9%. This investigation of chain exchange behaviors in BCP NPs having architectural and compositional complexity and the ability to moderate chain motion through tailoring the CLD is expected to be valuable for understanding the dynamic nature of BCP self-assemblies and diversifying the self-assembled structures adopted by these systems. These efforts may guide the rational construction of novel polymer NPs for potential use, for example, as drug delivery platforms and nanoreactors.
Identifiants
pubmed: 35281559
doi: 10.3389/fchem.2022.833307
pii: 833307
pmc: PMC8906501
doi:
Types de publication
Journal Article
Langues
eng
Pagination
833307Informations de copyright
Copyright © 2022 Li, Davis, Mays, Wang and Kilbey.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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