Working Memory During Late Pregnancy: Associations With Antepartum and Postpartum Depression Symptoms.
Edinburgh Postnatal Depression Scale
antepartum depression
postpartum depression
short-term memory/attention
working memory
Journal
Frontiers in global women's health
ISSN: 2673-5059
Titre abrégé: Front Glob Womens Health
Pays: Switzerland
ID NLM: 101776281
Informations de publication
Date de publication:
2022
2022
Historique:
received:
22
11
2021
accepted:
27
01
2022
entrez:
14
3
2022
pubmed:
15
3
2022
medline:
15
3
2022
Statut:
epublish
Résumé
Few studies, with conflicting results, report on the association between memory performance and depressive symptoms during the perinatal period. In this study, we aimed to evaluate whether memory performance during late pregnancy is associated with antepartum (APD) and postpartum depression (PPD) symptoms. We conducted a prospective follow-up of 283 pregnant women, nested within a large cohort of women enrolled in the BASIC study in Uppsala University hospital between 2009 and 2019. The Wechsler Digit Span Task (forward-DSF, backward-DSB and total score-DST) was performed to evaluate short-term memory/attention (DSF) and working memory (DSB) around the 38th gestational week; the Edinburgh Postnatal Depression Scale (EPDS), evaluating depressive symptoms, was filled out at 17, 32, 38 gestational weeks, as well as at 6 weeks postpartum. Unadjusted and multivariate logistic regression was used to assess the association between performance on the Digit Span Task and outcome, namely depressive symptoms (using a cut-off of 12 points on the EPDS) at 38 gestational weeks, as well as at 6 weeks postpartum. APD symptoms were not significantly associated with DSF ( There was no significant association between working and short-term memory performance and APD symptoms. Among all women, but especially non-depressed earlier in life and/or at antepartum, those scoring high on the forward memory test, i.e., short-term memory, had a higher risk for PPD. Future studies are required to further explore the pathophysiology behind and the predictive value of these associations.
Sections du résumé
Background
UNASSIGNED
Few studies, with conflicting results, report on the association between memory performance and depressive symptoms during the perinatal period. In this study, we aimed to evaluate whether memory performance during late pregnancy is associated with antepartum (APD) and postpartum depression (PPD) symptoms.
Method
UNASSIGNED
We conducted a prospective follow-up of 283 pregnant women, nested within a large cohort of women enrolled in the BASIC study in Uppsala University hospital between 2009 and 2019. The Wechsler Digit Span Task (forward-DSF, backward-DSB and total score-DST) was performed to evaluate short-term memory/attention (DSF) and working memory (DSB) around the 38th gestational week; the Edinburgh Postnatal Depression Scale (EPDS), evaluating depressive symptoms, was filled out at 17, 32, 38 gestational weeks, as well as at 6 weeks postpartum. Unadjusted and multivariate logistic regression was used to assess the association between performance on the Digit Span Task and outcome, namely depressive symptoms (using a cut-off of 12 points on the EPDS) at 38 gestational weeks, as well as at 6 weeks postpartum.
Results
UNASSIGNED
APD symptoms were not significantly associated with DSF (
Conclusion
UNASSIGNED
There was no significant association between working and short-term memory performance and APD symptoms. Among all women, but especially non-depressed earlier in life and/or at antepartum, those scoring high on the forward memory test, i.e., short-term memory, had a higher risk for PPD. Future studies are required to further explore the pathophysiology behind and the predictive value of these associations.
Identifiants
pubmed: 35284907
doi: 10.3389/fgwh.2022.820353
pmc: PMC8904422
doi:
Types de publication
Journal Article
Langues
eng
Pagination
820353Informations de copyright
Copyright © 2022 Liakea, KC, Bränn, Fransson, Sundström Poromaa, Papadopoulos and Skalkidou.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
J Psychiatr Res. 2009 Jun;43(9):855-63
pubmed: 19128810
J Mol Endocrinol. 2018 Aug;61(2):T199-T210
pubmed: 29440314
Arch Clin Neuropsychol. 2002 Aug;17(6):547-65
pubmed: 14591855
Mem Cognit. 2019 May;47(4):575-588
pubmed: 30478520
BMJ Open. 2019 Oct 22;9(10):e031514
pubmed: 31641004
Epidemiology. 2004 Sep;15(5):615-25
pubmed: 15308962
Transl Psychiatry. 2021 Oct 20;11(1):543
pubmed: 34671011
Clin Obstet Gynecol. 2018 Sep;61(3):591-603
pubmed: 29596076
Can J Exp Psychol. 2011 Mar;65(1):27-37
pubmed: 21443327
J Psychosom Obstet Gynaecol. 2004 Mar;25(1):23-34
pubmed: 15376402
J Affect Disord. 2014 Jun;162:1-7
pubmed: 24766996
J Clin Exp Neuropsychol. 2014;36(5):528-39
pubmed: 24820853
Brain Behav. 2016 Jul 21;6(10):e00527
pubmed: 27781141
J Intell. 2017 Jun 16;5(2):
pubmed: 31162417
Arch Womens Ment Health. 2015 Jun;18(3):539-46
pubmed: 25369905
Psychoneuroendocrinology. 2010 Sep;35(8):1148-55
pubmed: 20304563
Psychoneuroendocrinology. 2021 Oct;132:105361
pubmed: 34333317
Eur J Obstet Gynecol Reprod Biol. 2004 Oct 15;116(2):125-30
pubmed: 15358452
J Clin Exp Neuropsychol. 2019 Feb;41(1):87-107
pubmed: 29973120
Curr Psychiatry Rep. 2019 Mar 2;21(3):20
pubmed: 30826881
Clin Obstet Gynecol. 2018 Sep;61(3):533-543
pubmed: 29659372
Horm Behav. 2015 Aug;74:218-27
pubmed: 26187710
Neuropsychologia. 1974 Jan;12(1):109-18
pubmed: 4821181
Lancet. 2014 Nov 15;384(9956):1800-19
pubmed: 25455250
Behav Res Ther. 2016 Jul;82:38-49
pubmed: 27203622
Emotion. 2012 Oct;12(5):1075-84
pubmed: 22023357
Psychoneuroendocrinology. 2001 May;26(4):339-62
pubmed: 11259856
Scand J Caring Sci. 1993;7(3):149-54
pubmed: 8108616
Exp Brain Res. 2000 Jul;133(1):23-32
pubmed: 10933207
Br J Psychiatry. 2010 Feb;196(2):126-32
pubmed: 20118458
J Affect Disord. 2013 Jul;149(1-3):67-74
pubmed: 23499163
Psychol Psychother. 2003 Mar;76(Pt 1):69-84
pubmed: 12689436
Eur J Pharmacol. 2010 Jan 10;626(1):83-6
pubmed: 19835870
J Adolesc Health. 2014 Jan;54(1):88-93
pubmed: 24060574
Open Access Maced J Med Sci. 2019 May 14;7(9):1555-1560
pubmed: 31198472
Behav Neurosci. 2012 Feb;126(1):73-85
pubmed: 21928875
Br J Psychiatry. 1987 Jun;150:782-6
pubmed: 3651732
Arch Womens Ment Health. 2005 Jun;8(2):97-104
pubmed: 15883652
Am J Geriatr Psychiatry. 2011 Jun;19(6):559-70
pubmed: 21606899
J Clin Exp Neuropsychol. 2010 Nov;32(9):986-95
pubmed: 20408003
J Clin Exp Neuropsychol. 2007 Nov;29(8):793-803
pubmed: 18030631
J Obstet Gynecol Neonatal Nurs. 2006 Nov-Dec;35(6):735-45
pubmed: 17105638
Clin Psychol Sci. 2019 Jan;7(1):93-109
pubmed: 30906675
Clin Exp Obstet Gynecol. 2015;42(5):605-9
pubmed: 26524807
Evol Psychol. 2012 Oct 10;10(4):659-87
pubmed: 23052608
Brain Lang. 2001 Jul;78(1):17-42
pubmed: 11412013
J Affect Disord. 2017 Aug 15;218:66-74
pubmed: 28458118