Genetic and environmental influences on quality of life: The COVID-19 pandemic as a natural experiment.
covid-19
heritability
natural experiment
quality of life
variance decomposition
well-being
Journal
Genes, brain, and behavior
ISSN: 1601-183X
Titre abrégé: Genes Brain Behav
Pays: England
ID NLM: 101129617
Informations de publication
Date de publication:
11 2022
11 2022
Historique:
revised:
20
12
2021
received:
10
11
2021
accepted:
04
01
2022
pubmed:
16
3
2022
medline:
19
11
2022
entrez:
15
3
2022
Statut:
ppublish
Résumé
By treating the coronavirus disease 2019 (COVID-19) pandemic as a natural experiment, we examine the influence of substantial environmental change (i.e., lockdown measures) on individual differences in quality of life (QoL) in the Netherlands. We compare QoL scores before the pandemic (N = 25,772) to QoL scores during the pandemic (N = 17,222) in a sample of twins and their family members. On a 10-point scale, we find a significant decrease in mean QoL from 7.73 (SD = 1.06) before the pandemic to 7.02 (SD = 1.36) during the pandemic (Cohen's d = 0.49). Additionally, variance decomposition shows an increase in unique environmental variance during the pandemic (0.30-1.08), and a decrease in the heritability estimate from 30.9% to 15.5%. We hypothesize that the increased environmental variance is the result of lockdown measures not impacting everybody equally. Whether these effects persist over longer periods and how they impact health inequalities remain topics for future investigation.
Identifiants
pubmed: 35289084
doi: 10.1111/gbb.12796
pmc: PMC9111595
doi:
Types de publication
Twin Study
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e12796Subventions
Organisme : European Research Council
ID : 771057
Pays : International
Informations de copyright
© 2022 The Authors. Genes, Brain and Behavior published by International Behavioural and Neural Genetics Society and John Wiley & Sons Ltd.
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