Cognitive decline and brainstem hypometabolism in long COVID: A case series.
brainstem lesions
cerebral FDG PET
cognitive deficits
long COVID
Journal
Brain and behavior
ISSN: 2162-3279
Titre abrégé: Brain Behav
Pays: United States
ID NLM: 101570837
Informations de publication
Date de publication:
04 2022
04 2022
Historique:
revised:
11
12
2021
received:
06
09
2021
accepted:
11
01
2022
pubmed:
16
3
2022
medline:
21
4
2022
entrez:
15
3
2022
Statut:
ppublish
Résumé
To assess FDG cerebral PET in patients suffering from cognitive impairment linked to Long COVID. The COVID pandemic has affected dozens of millions of people around the world and has resulted in the deaths of more than 3 million people. Following the acute forms, it has been reported sometimes long forms of COVID, with involvements of several organs including the brain. Neurological complications can include cognitive disturbances (brain fog) that are very common and can seriously disturb the life of patients. Fluorodeoxyglucose PETs were performed in 3 patients with cognitive decline following COVID infection. We report here 3 cases of brain fog with major hypometabolic areas of the pons revealed by the cerebral FDG PET. The dysfunction of the locus coeruleus in these patients could partly explain the cognitive disorders observed. Further studies involving larger cohorts of patients suffering from cognitive dysfunction will be needed to determine if the brainstem is frequently affected in these patients.
Identifiants
pubmed: 35290729
doi: 10.1002/brb3.2513
pmc: PMC9014998
doi:
Substances chimiques
Radiopharmaceuticals
0
Fluorodeoxyglucose F18
0Z5B2CJX4D
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e2513Informations de copyright
© 2022 The Authors. Brain and Behavior published by Wiley Periodicals LLC.
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