Para-aortic lymph node involvement in cervical cancer: Implications for staging, outcome and treatment.
Locally advanced cervical cancer
para-aortic lymph nodes
staging
treatment
Journal
The Indian journal of medical research
ISSN: 0971-5916
Titre abrégé: Indian J Med Res
Pays: India
ID NLM: 0374701
Informations de publication
Date de publication:
Aug 2021
Aug 2021
Historique:
entrez:
17
3
2022
pubmed:
18
3
2022
medline:
12
4
2022
Statut:
ppublish
Résumé
Locally advanced cervical cancer with the involvement of para-aortic lymph nodes (PALN) is a common occurrence in low-income and low-middle-income countries. With the incorporation of PALN in the recent FIGO staging, therapeutic management becomes crucial. There are varied presentations of this group which may range from microscopic involvement to extensive lymphadenopathy. Various imaging modalities have been studied to accurately diagnose PALN metastases without surgical intervention, while some investigators have studied the survival benefit of para-aortic lymph node dissection for accurate staging and guiding extent of radiation. With recent advances in radiation therapy, its application to treat bulky nodal metastases and the role of prophylactic irradiation have been reported. In this review, the available evidence and the scope of further interventions is presented.
Identifiants
pubmed: 35295007
pii: IndianJMedRes_2021_154_2_0_338111
doi: 10.4103/ijmr.IJMR_4183_20
pmc: PMC9131762
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
267-272Déclaration de conflit d'intérêts
None
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