Optimization of Human Neural Progenitor Cells for an Imaging-Based High-Throughput Phenotypic Profiling Assay for Developmental Neurotoxicity Screening.

computational toxicology developmental neurotoxicology high-throughput (HT) approaches human-derived cells phenotypic profiling

Journal

Frontiers in toxicology
ISSN: 2673-3080
Titre abrégé: Front Toxicol
Pays: Switzerland
ID NLM: 101777990

Informations de publication

Date de publication:
2021
Historique:
received: 28 10 2021
accepted: 27 12 2021
entrez: 17 3 2022
pubmed: 18 3 2022
medline: 18 3 2022
Statut: epublish

Résumé

Studies in

Identifiants

pubmed: 35295155
doi: 10.3389/ftox.2021.803987
pii: 803987
pmc: PMC8915842
doi:

Types de publication

Journal Article

Langues

eng

Pagination

803987

Informations de copyright

Copyright © 2022 Culbreth, Nyffeler, Willis and Harrill.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The U.S. Environmental Protection Agency has provided administrative review and approved this manuscript for publication. The views expressed in this manuscript, however, are those of the authors and do not necessarily reflect U.S. EPA policies. Reference to commercial products does not constitute endorsement.

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Auteurs

Megan Culbreth (M)

Center for Computational Toxicology and Exposure, Office of Research and Development, U.S. Environmental Protection Agency, Durham, NC, United States.

Johanna Nyffeler (J)

Center for Computational Toxicology and Exposure, Office of Research and Development, U.S. Environmental Protection Agency, Durham, NC, United States.
Oak Ridge Institute for Science and Education (ORISE) Postdoctoral Fellow, Oak Ridge, TN, United States.

Clinton Willis (C)

Center for Computational Toxicology and Exposure, Office of Research and Development, U.S. Environmental Protection Agency, Durham, NC, United States.

Joshua A Harrill (JA)

Center for Computational Toxicology and Exposure, Office of Research and Development, U.S. Environmental Protection Agency, Durham, NC, United States.

Classifications MeSH