Accelerated Muscle Deoxygenation in Aerobically Fit Subjects During Exhaustive Exercise Is Associated With the
aerobic metabolism
cycling
exhaustive pedaling
gene
oxygen saturation
Journal
Frontiers in sports and active living
ISSN: 2624-9367
Titre abrégé: Front Sports Act Living
Pays: Switzerland
ID NLM: 101765780
Informations de publication
Date de publication:
2022
2022
Historique:
received:
14
11
2021
accepted:
24
01
2022
entrez:
17
3
2022
pubmed:
18
3
2022
medline:
18
3
2022
Statut:
epublish
Résumé
The insertion/deletion (I/D) polymorphism in the gene for the major regulator of vascular tone, angiotensin-converting enzyme-insertion/deletion (ACE-I/D) affects muscle capillarization and mitochondrial biogenesis with endurance training. We tested whether changes of leg muscle oxygen saturation (SmO In total, 34 healthy subjects (age: 31.8 ± 10.2 years, 17 male, 17 female) performed an incremental exercise test to exhaustion. SmO Deoxygenation with exercise was comparable in VAS and GAS ( Aerobically fit subjects demonstrated increased rates of leg muscle deoxygenation and reoxygenation. Together with the higher muscle deoxygenation in aerobically fit ACE-II genotypes, this suggests that an ACE-I/D genotype-based personalization of training protocols might serve to best improve aerobic performance.
Identifiants
pubmed: 35295536
doi: 10.3389/fspor.2022.814975
pmc: PMC8918772
doi:
Types de publication
Journal Article
Langues
eng
Pagination
814975Informations de copyright
Copyright © 2022 Gasser, Franchi, Ruoss, Frei, Popp, Niederseer, Catuogno, Frey and Flück.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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