Immune regulation by fungal strain diversity in inflammatory bowel disease.

Animals CRISPR-Cas Systems Candida albicans Fungi / genetics Gastrointestinal Microbiome Genetic Variation Humans Immunity Inflammation Inflammatory Bowel Diseases Mammals Microbiota Mycobiome

Journal

Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462

Informations de publication

Date de publication:
03 2022
Historique:
received: 05 03 2020
accepted: 02 02 2022
pubmed: 18 3 2022
medline: 16 4 2022
entrez: 17 3 2022
Statut: ppublish

Résumé

The fungal microbiota (mycobiota) is an integral part of the complex multikingdom microbial community colonizing the mammalian gastrointestinal tract and has an important role in immune regulation

Identifiants

DOI: 10.1038/s41586-022-04502-w PMID: 35296857 PMC: PMC9166917
pubmed: 35296857
doi: 10.1038/s41586-022-04502-w
pii: 10.1038/s41586-022-04502-w
pmc: PMC9166917
mid: NIHMS1790518
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

672-678

Subventions

Organisme : NIDCR NIH HHS
ID : R37 DE022550
Pays : United States
Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : NIDDK NIH HHS
ID : F32 DK120228
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK113136
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK121977
Pays : United States
Organisme : NIAID NIH HHS
ID : R21 AI146957
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI163007
Pays : United States
Organisme : Wellcome Trust
ID : 214229_Z_18_Z
Pays : United Kingdom

Commentaires et corrections

Type : CommentIn
Type : CommentIn
Type : CommentIn
Type : ErratumIn

Informations de copyright

© 2022. The Author(s), under exclusive licence to Springer Nature Limited.

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Auteurs

Xin V Li (XV)

Gastroenterology and Hepatology Division, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.
The Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY, USA.
ORCID: 0000-0002-9444-8214

Irina Leonardi (I)

Gastroenterology and Hepatology Division, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.
The Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY, USA.
ORCID: 0000-0002-0369-7371

Gregory G Putzel (GG)

The Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY, USA.

Alexa Semon (A)

Gastroenterology and Hepatology Division, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.
The Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY, USA.
ORCID: 0000-0002-0551-1446

William D Fiers (WD)

Gastroenterology and Hepatology Division, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.
The Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY, USA.

Takato Kusakabe (T)

Gastroenterology and Hepatology Division, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.
The Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY, USA.

Woan-Yu Lin (WY)

Gastroenterology and Hepatology Division, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.
The Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY, USA.
Immunology and Microbial Pathogenesis Program, Weill Cornell Graduate School of Medical Sciences, Weill Cornell Medicine, Cornell University, New York, NY, USA.

Iris H Gao (IH)

Gastroenterology and Hepatology Division, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.
The Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY, USA.
Immunology and Microbial Pathogenesis Program, Weill Cornell Graduate School of Medical Sciences, Weill Cornell Medicine, Cornell University, New York, NY, USA.
ORCID: 0000-0001-6514-3019

Itai Doron (I)

Gastroenterology and Hepatology Division, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.
The Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY, USA.

Alejandra Gutierrez-Guerrero (A)

Gastroenterology and Hepatology Division, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.
The Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY, USA.

Meghan B DeCelie (MB)

The Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY, USA.

Guilhermina M Carriche (GM)

Gastroenterology and Hepatology Division, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.
The Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY, USA.

Marissa Mesko (M)

The Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY, USA.
ORCID: 0000-0002-4788-8794

Chen Yang (C)

Department of Pathology, Yale School of Medicine, Yale University, New Haven, CT, USA.
ORCID: 0000-0002-6371-5930

Julian R Naglik (JR)

Centre for Host-Microbiome Interactions, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London, UK.
ORCID: 0000-0002-8072-7917

Bernhard Hube (B)

Department of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knoell Institute, Jena, Germany.
Institute of Microbiology, FriedrichSchiller University, Jena, Germany.
ORCID: 0000-0002-6028-0425

Ellen J Scherl (EJ)

Gastroenterology and Hepatology Division, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.
The Jill Roberts Center for Inflammatory Bowel Disease, Weill Cornell Medicine, New York, NY, USA.

Iliyan D Iliev (ID)

Gastroenterology and Hepatology Division, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA. iliev@med.cornell.edu.
The Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY, USA. iliev@med.cornell.edu.
Immunology and Microbial Pathogenesis Program, Weill Cornell Graduate School of Medical Sciences, Weill Cornell Medicine, Cornell University, New York, NY, USA. iliev@med.cornell.edu.
Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY, USA. iliev@med.cornell.edu.
ORCID: 0000-0003-0884-9749

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Immune regulation by fungal strain diversity...
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Épigenèse génétique › Extinction de l'expression des gènes › Systèmes CRISPR-Cas › Immune regulation by fungal strain diversity...
questionsmedicales.fr › Eucaryotes › Champignons › Levures › Candida › Candida albicans › Immune regulation by fungal strain diversity...
questionsmedicales.fr › Eucaryotes › Champignons › Immune regulation by fungal strain diversity...
questionsmedicales.fr › Environnement et santé publique › Environnement › Écosystème › Biodiversité › Biote › Microbiote › Microbiome gastro-intestinal › Immune regulation by fungal strain diversity...
questionsmedicales.fr › Phénomènes génétiques › Variation génétique › Immune regulation by fungal strain diversity...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Immune regulation by fungal strain diversity...
questionsmedicales.fr › Phénomènes du système immunitaire › Immunité › Immune regulation by fungal strain diversity...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Inflammation › Immune regulation by fungal strain diversity...
questionsmedicales.fr › Maladies de l'appareil digestif › Maladies gastro-intestinales › Maladies intestinales › Maladies inflammatoires intestinales › Immune regulation by fungal strain diversity...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Immune regulation by fungal strain diversity...
questionsmedicales.fr › Environnement et santé publique › Environnement › Écosystème › Biodiversité › Biote › Microbiote › Immune regulation by fungal strain diversity...
questionsmedicales.fr › Environnement et santé publique › Environnement › Écosystème › Biodiversité › Biote › Microbiote › Mycobiome › Immune regulation by fungal strain diversity...