Efficacy of Individualized Homeopathic Medicines in Treatment of Acne Vulgaris: A Double-Blind, Randomized, Placebo-Controlled Trial.


Journal

Homeopathy : the journal of the Faculty of Homeopathy
ISSN: 1476-4245
Titre abrégé: Homeopathy
Pays: Germany
ID NLM: 101140517

Informations de publication

Date de publication:
Nov 2022
Historique:
pubmed: 18 3 2022
medline: 18 11 2022
entrez: 17 3 2022
Statut: ppublish

Résumé

Acne is estimated to affect 9.4% of the global population, making it the 8 In this double-blind, randomized, placebo-controlled trial conducted at the National Institute of Homoeopathy, India, 126 patients suffering from AV were randomized in a 1:1 ratio to receive either IHM (verum) in centesimal potencies or identical-looking placebo (control). The primary outcome measure was the Global Acne Grading System score; secondary outcomes were the Cardiff Acne Disability Index and Dermatology Life Quality Index questionnaires - all measured at baseline and 3 months after the intervention. Group differences and effect sizes (Cohen's Overall, improvements were greater in the IHM group than placebo, with small to medium effect sizes after 3 months of intervention; however, the inter-group differences were statistically non-significant. There was non-significant direction of effect favoring homeopathy against placebo in the treatment of AV. CTRI/2018/11/016248; UTN: U1111-1221-8164.

Sections du résumé

BACKGROUND
Acne is estimated to affect 9.4% of the global population, making it the 8
METHODS
In this double-blind, randomized, placebo-controlled trial conducted at the National Institute of Homoeopathy, India, 126 patients suffering from AV were randomized in a 1:1 ratio to receive either IHM (verum) in centesimal potencies or identical-looking placebo (control). The primary outcome measure was the Global Acne Grading System score; secondary outcomes were the Cardiff Acne Disability Index and Dermatology Life Quality Index questionnaires - all measured at baseline and 3 months after the intervention. Group differences and effect sizes (Cohen's
RESULTS
Overall, improvements were greater in the IHM group than placebo, with small to medium effect sizes after 3 months of intervention; however, the inter-group differences were statistically non-significant.
CONCLUSION
There was non-significant direction of effect favoring homeopathy against placebo in the treatment of AV.
TRIAL REGISTRATION
CTRI/2018/11/016248; UTN: U1111-1221-8164.

Identifiants

pubmed: 35299272
doi: 10.1055/s-0041-1739397
doi:

Substances chimiques

Materia Medica 0

Types de publication

Randomized Controlled Trial Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

240-251

Informations de copyright

Faculty of Homeopathy. This article is published by Thieme.

Déclaration de conflit d'intérêts

None declared.

Auteurs

Shruti Rai (S)

Department of Organon of Medicine and Homoeopathic Philosophy, National Institute of Homoeopathy, Salt Lake, Kolkata, West Bengal, India.

Gobind Narayan Gupta (GN)

Department of Organon of Medicine and Homoeopathic Philosophy, National Institute of Homoeopathy, Salt Lake, Kolkata, West Bengal, India.

Subhas Singh (S)

Department of Organon of Medicine and Homoeopathic Philosophy, National Institute of Homoeopathy, Salt Lake, Kolkata, West Bengal, India.

James Michael (J)

Department of Organon of Medicine and Homoeopathic Philosophy, National Institute of Homoeopathy, Salt Lake, Kolkata, West Bengal, India.

Pankhuri Misra (P)

Department of Materia Medica, National Institute of Homoeopathy, Salt Lake, Kolkata, West Bengal, India.

Bharti Gupta (B)

Department of Paediatrics, National Institute of Homoeopathy, Salt Lake, Kolkata, West Bengal, India.

Suman Singh (S)

Department of Organon of Medicine and Homoeopathic Philosophy, National Institute of Homoeopathy, Salt Lake, Kolkata, West Bengal, India.

Akshaya Prakash (A)

Department of Organon of Medicine and Homoeopathic Philosophy, National Institute of Homoeopathy, Salt Lake, Kolkata, West Bengal, India.

Maneela Tomar (M)

Department of Organon of Medicine and Homoeopathic Philosophy, National Institute of Homoeopathy, Salt Lake, Kolkata, West Bengal, India.

Satarupa Sadhukhan (S)

Department of Organon of Medicine and Homoeopathic Philosophy, National Institute of Homoeopathy, Salt Lake, Kolkata, West Bengal, India.

Munmun Koley (M)

East Bishnupur State Homoeopathic Dispensary, Chandi Daulatabad Block Primary Health Centre, South 24 Parganas, West Bengal, under Department of Health & Family Welfare, Govt. of West Bengal, India.

Subhranil Saha (S)

Department of Repertory, D.N. De Homoeopathic Medical College and Hospital, Govt. of West Bengal, Tangra, Kolkata, West Bengal, India.

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