Lab-scale photobioreactor systems: principles, applications, and scalability.
Lab-scale reactors
Microalgae
Photobioreactor
Scale-up
Journal
Bioprocess and biosystems engineering
ISSN: 1615-7605
Titre abrégé: Bioprocess Biosyst Eng
Pays: Germany
ID NLM: 101088505
Informations de publication
Date de publication:
May 2022
May 2022
Historique:
received:
22
10
2021
accepted:
14
02
2022
pubmed:
19
3
2022
medline:
27
4
2022
entrez:
18
3
2022
Statut:
ppublish
Résumé
Phototrophic microorganisms that convert carbon dioxide are being explored for their capacity to solve different environmental issues and produce bioactive compounds for human therapeutics and as food additives. Full-scale phototrophic cultivation of microalgae and cyanobacteria can be done in open ponds or closed photobioreactor systems, which have a broad range of volumes. This review focuses on laboratory-scale photobioreactors and their different designs. Illuminated microtiter plates and microfluidic devices offer an option for automated high-throughput studies with microalgae. Illuminated shake flasks are used for simple uncontrolled batch studies. The application of illuminated bubble column reactors strongly emphasizes homogenous gas distribution, while illuminated flat plate bioreactors offer high and uniform light input. Illuminated stirred-tank bioreactors facilitate the application of very well-defined reaction conditions. Closed tubular photobioreactors as well as open photobioreactors like small-scale raceway ponds and thin-layer cascades are applied as scale-down models of the respective large-scale bioreactors. A few other less common designs such as illuminated plastic bags or aquarium tanks are also used mainly because of their relatively low cost, but up-scaling of these designs is challenging with additional light-driven issues. Finally, this review covers recommendations on the criteria for photobioreactor selection and operation while up-scaling of phototrophic bioprocesses with microalgae or cyanobacteria.
Identifiants
pubmed: 35303143
doi: 10.1007/s00449-022-02711-1
pii: 10.1007/s00449-022-02711-1
pmc: PMC9033726
doi:
Substances chimiques
Carbon Dioxide
142M471B3J
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
791-813Informations de copyright
© 2022. The Author(s).
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