A cross-sectional MR study of body fat volumes and distribution in chronic schizophrenia.


Journal

Schizophrenia (Heidelberg, Germany)
ISSN: 2754-6993
Titre abrégé: Schizophrenia (Heidelb)
Pays: Germany
ID NLM: 9918367987006676

Informations de publication

Date de publication:
18 03 2022
Historique:
received: 18 10 2021
accepted: 01 02 2022
entrez: 19 3 2022
pubmed: 20 3 2022
medline: 20 3 2022
Statut: epublish

Résumé

People with schizophrenia show higher risk for abdominal obesity than the general population, which could contribute to excess mortality. However, it is unclear whether this is driven by alterations in abdominal fat partitioning. Here, we test the hypothesis that individuals with schizophrenia show a higher proportion of visceral to total body fat measured using magnetic resonance imaging (MRI). We recruited 38 participants with schizophrenia and 38 healthy controls matched on age, sex, ethnicity, and body mass index. We found no significant differences in body fat distribution between groups, suggesting that increased abdominal obesity in schizophrenia is not associated with altered fat distribution.

Identifiants

pubmed: 35304889
doi: 10.1038/s41537-022-00233-z
pii: 10.1038/s41537-022-00233-z
pmc: PMC8933542
doi:

Types de publication

Journal Article

Langues

eng

Pagination

24

Subventions

Organisme : Medical Research Council
ID : MC_U120097115
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/N027078/1
Pays : United Kingdom

Informations de copyright

© 2022. The Author(s).

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Auteurs

Emanuele F Osimo (EF)

MRC London Institute of Medical Sciences, Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, Hammersmith Hospital Campus, London, UK. eosimo@ic.ac.uk.
Department of Psychiatry, University of Cambridge, Cambridge, UK. eosimo@ic.ac.uk.
Cambridgeshire and Peterborough NHS Foundation Trust, Cambridge, UK. eosimo@ic.ac.uk.
South London and Maudsley NHS Foundation Trust, London, UK. eosimo@ic.ac.uk.

Stefan P Brugger (SP)

Cardiff University Brain Research and Imaging Centre, School of Psychology, Cardiff University, London, UK.

E Louise Thomas (EL)

Research Centre for Optimal Health, School of Life Sciences, University of Westminster, London, UK.

Oliver D Howes (OD)

MRC London Institute of Medical Sciences, Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, Hammersmith Hospital Campus, London, UK. oliver.howes@lms.mrc.ac.uk.
South London and Maudsley NHS Foundation Trust, London, UK. oliver.howes@lms.mrc.ac.uk.
Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK. oliver.howes@lms.mrc.ac.uk.

Classifications MeSH