Diabetes reversal: Update on current knowledge and proposal of prediction score parameters for diabetes remission.

Diabetes remission prediction score parameters Diabetes reversal Diabetes subtypes Diet Lifestyle modification Low calorie diet Low carb diet

Journal

Diabetes & metabolic syndrome
ISSN: 1878-0334
Titre abrégé: Diabetes Metab Syndr
Pays: Netherlands
ID NLM: 101462250

Informations de publication

Date de publication:
Apr 2022
Historique:
received: 30 07 2021
revised: 06 03 2022
accepted: 08 03 2022
pubmed: 21 3 2022
medline: 4 5 2022
entrez: 20 3 2022
Statut: ppublish

Résumé

The field of diabetes reversal is continuously evolving. Strategies for implementing diabetes care towards diabetes reversal are still being worked out. We aim to analyse data from available literature to ascertain factors allowing patient centric dietary approach to achieve diabetes reversal in clinical practice. In this exploratory review, an update on current knowledge is presented to delineate factors driving diabetes remission in an individual based on major studies in the field. This knowledge is then applied to subtypes of type 2 diabetes to optimise dietary approach for reversal of diabetes. Shorter duration of diabetes, lesser number of medicines needed to achieve euglycemia and 15 kg weight loss are common factors favouring diabetes remission in all major studies. A patient centric approach to diabetes reversal taking into account the recently described diabetes subtypes is being proposed to improve the proportion of patients achieving remission. We also propose the parameters of a novel diabetes remission prediction score, based on patient motivation, interaction with the care-team, level of diabetes self-care and the intent of the care-team.

Sections du résumé

BACKGROUND AND AIM OBJECTIVE
The field of diabetes reversal is continuously evolving. Strategies for implementing diabetes care towards diabetes reversal are still being worked out. We aim to analyse data from available literature to ascertain factors allowing patient centric dietary approach to achieve diabetes reversal in clinical practice.
METHODS METHODS
In this exploratory review, an update on current knowledge is presented to delineate factors driving diabetes remission in an individual based on major studies in the field. This knowledge is then applied to subtypes of type 2 diabetes to optimise dietary approach for reversal of diabetes.
RESULTS AND CONCLUSION CONCLUSIONS
Shorter duration of diabetes, lesser number of medicines needed to achieve euglycemia and 15 kg weight loss are common factors favouring diabetes remission in all major studies. A patient centric approach to diabetes reversal taking into account the recently described diabetes subtypes is being proposed to improve the proportion of patients achieving remission. We also propose the parameters of a novel diabetes remission prediction score, based on patient motivation, interaction with the care-team, level of diabetes self-care and the intent of the care-team.

Identifiants

pubmed: 35306265
pii: S1871-4021(22)00066-2
doi: 10.1016/j.dsx.2022.102452
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

102452

Informations de copyright

Copyright © 2022 Diabetes India. Published by Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest We declare that there are no Conflicts of interest to report regarding this manuscript.

Auteurs

Rajiv Singla (R)

Onliv Health, USA and Consultant Endocrinologist, Kalpavriksh Healthcare, Dwarka, New Delhi, India. Electronic address: docrajivsingla@gmail.com.

Geetu Gupta (G)

Kalpavriksh Healthcare, Dwarka, New Delhi, India.

Deep Dutta (D)

CEDAR Superspeciality Healthcare, Dwarka, New Delhi, India.

Nishant Raizada (N)

Department of Endocrinology, UCMS and GTB Hospital, New Delhi, India.

Sameer Aggarwal (S)

Endocrinology and Metabolism, Apex Plus Superspeciality Hospital, Rohtak, India.

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