The Biological Process of Aging and the Impact of Ionizing Radiation.


Journal

Seminars in radiation oncology
ISSN: 1532-9461
Titre abrégé: Semin Radiat Oncol
Pays: United States
ID NLM: 9202882

Informations de publication

Date de publication:
04 2022
Historique:
entrez: 21 3 2022
pubmed: 22 3 2022
medline: 26 4 2022
Statut: ppublish

Résumé

Ionizing radiation is used to create models of accelerated aging because the processes of aging and radiation injury share common elements. In this chapter we review the biological processes of aging and the similarities and impact of ionizing radiation on those processes. The information draws on data from laboratory studies and from epidemiology studies of radiation exposure victims. The chapter reviews the effects of radiation on DNA, cells, and organs systems on aged adults. The science of aging and the effect of radiation on the aging process are areas of active research and our understanding is evolving.

Identifiants

pubmed: 35307120
pii: S1053-4296(21)00079-5
doi: 10.1016/j.semradonc.2021.11.011
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

172-178

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Auteurs

Mohammed Al-Jumayli (M)

Senior Adult Oncology Program, Moffitt Cancer Canter, Tampa, FL.

Stephen L Brown (SL)

Department of Radiation Oncology, Henry Ford Cancer Institute, Henry Ford Health System, Detroit, MI.

Indrin J Chetty (IJ)

Department of Radiation Oncology, Henry Ford Cancer Institute, Henry Ford Health System, Detroit, MI.

Martine Extermann (M)

Senior Adult Oncology Program, Moffitt Cancer Canter, Tampa, FL. Electronic address: martine.extermann@moffitt.org.

Benjamin Movsas (B)

Department of Radiation Oncology, Henry Ford Cancer Institute, Henry Ford Health System, Detroit, MI.

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Classifications MeSH