Synthesis and evaluation of highly selective quinazoline-2,4-dione ligands for sphingosine-1-phosphate receptor 2.


Journal

RSC medicinal chemistry
ISSN: 2632-8682
Titre abrégé: RSC Med Chem
Pays: England
ID NLM: 101759460

Informations de publication

Date de publication:
23 Feb 2022
Historique:
received: 08 11 2021
accepted: 22 12 2021
entrez: 21 3 2022
pubmed: 22 3 2022
medline: 22 3 2022
Statut: epublish

Résumé

A series of twenty-nine new quinazoline-2,4-dione compounds were synthesized and their IC

Identifiants

pubmed: 35308025
doi: 10.1039/d1md00357g
pii: d1md00357g
pmc: PMC8864552
doi:

Types de publication

Journal Article

Langues

eng

Pagination

202-207

Subventions

Organisme : NINDS NIH HHS
ID : R01 NS075321
Pays : United States
Organisme : NINDS NIH HHS
ID : R01 NS103957
Pays : United States
Organisme : NINDS NIH HHS
ID : R01 NS103988
Pays : United States
Organisme : NINDS NIH HHS
ID : R01 NS107281
Pays : United States

Informations de copyright

This journal is © The Royal Society of Chemistry.

Déclaration de conflit d'intérêts

There are no conflicts to declare.

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Auteurs

Zonghua Luo (Z)

Department of Radiology, Washington University School of Medicine St. Louis MO 63110 USA zhudetu@wustl.edu.
School of Biomedical Engineering, ShanghaiTech University Shanghai 201210 China.

Hui Liu (H)

Department of Radiology, Washington University School of Medicine St. Louis MO 63110 USA zhudetu@wustl.edu.

Yanbo Yu (Y)

Department of Radiology, Washington University School of Medicine St. Louis MO 63110 USA zhudetu@wustl.edu.

Robert J Gropler (RJ)

Department of Radiology, Washington University School of Medicine St. Louis MO 63110 USA zhudetu@wustl.edu.

Robyn S Klein (RS)

Department of Medicine, Washington University School of Medicine St. Louis MO 63110 USA.
Department of Neuroscience, Washington University School of Medicine St. Louis MO 63110 USA.
Department of Pathology & Immunology, Washington University School of Medicine St. Louis MO 63110 USA.

Zhude Tu (Z)

Department of Radiology, Washington University School of Medicine St. Louis MO 63110 USA zhudetu@wustl.edu.

Classifications MeSH