Effects of remifentanil on the recovery quality among pediatric candidates for dental procedures under general anesthesia.
Child
general anesthesia
propofol
remifentanil
Journal
Dental research journal
ISSN: 1735-3327
Titre abrégé: Dent Res J (Isfahan)
Pays: Iran
ID NLM: 101471186
Informations de publication
Date de publication:
2022
2022
Historique:
received:
13
04
2021
revised:
15
09
2021
accepted:
30
09
2021
entrez:
21
3
2022
pubmed:
22
3
2022
medline:
22
3
2022
Statut:
epublish
Résumé
Remifentanil is a short-acting synthetic opioid, seems to facilitate hospital discharge, induce less agitation and better recovery quality. The aim of this study was to investigate the effects of remifentanil on the quality of recovery among healthy children who were candidate for dental procedures under general anesthesia. This study was a double blind randomized controlled clinical trial on healthy children who referred to the Department of Pediatric dentistry, School of Dentistry, Isfahan University of Medical Sciences. Both groups were anaesthetized using 5 mg/kg thiopental sodium, 1 μg/kg fentanyl and 0.6 μg/kg atracurium. The first group received propofol to maintain anesthesia and the second group was given remifentanil along with propofol. Then, the time span to regain consciousness, level of agitation during recovery and time of discharge were monitored and compared between the two groups. Data were analyzed using the Mann-Whitney U-test, and the Kruskal-Wallis test at Findings showed that the propofol + remifentanil group recovered faster than the propofol group. Chi-square test showed a significant difference in recovery time between the two groups ( Combination of propofol and remifentanil significantly reduced the time taken for recovery, discharge and agitation level compared to propofol.
Sections du résumé
Background
UNASSIGNED
Remifentanil is a short-acting synthetic opioid, seems to facilitate hospital discharge, induce less agitation and better recovery quality. The aim of this study was to investigate the effects of remifentanil on the quality of recovery among healthy children who were candidate for dental procedures under general anesthesia.
Materials and Methods
UNASSIGNED
This study was a double blind randomized controlled clinical trial on healthy children who referred to the Department of Pediatric dentistry, School of Dentistry, Isfahan University of Medical Sciences. Both groups were anaesthetized using 5 mg/kg thiopental sodium, 1 μg/kg fentanyl and 0.6 μg/kg atracurium. The first group received propofol to maintain anesthesia and the second group was given remifentanil along with propofol. Then, the time span to regain consciousness, level of agitation during recovery and time of discharge were monitored and compared between the two groups. Data were analyzed using the Mann-Whitney U-test, and the Kruskal-Wallis test at
Results
UNASSIGNED
Findings showed that the propofol + remifentanil group recovered faster than the propofol group. Chi-square test showed a significant difference in recovery time between the two groups (
Conclusion
UNASSIGNED
Combination of propofol and remifentanil significantly reduced the time taken for recovery, discharge and agitation level compared to propofol.
Identifiants
pubmed: 35308454
doi: 10.4103/1735-3327.338778
pii: DRJ-19-15
pmc: PMC8927957
doi:
Types de publication
Journal Article
Langues
eng
Pagination
15Informations de copyright
Copyright: © 2022 Dental Research Journal.
Déclaration de conflit d'intérêts
The authors of this manuscript declare that they have no conflicts of interest, real or perceived, financial or nonfinancial in this article.
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