Comparative Assessment of the Effects of Hydroxyethyl Starch and Normal Saline on Severe Hypotension in Patients with Aluminum Phosphide Poisoning: A Retrospective Study.
Journal
Journal of toxicology
ISSN: 1687-8191
Titre abrégé: J Toxicol
Pays: Egypt
ID NLM: 101519097
Informations de publication
Date de publication:
2022
2022
Historique:
received:
14
10
2021
revised:
17
12
2021
accepted:
05
02
2022
entrez:
21
3
2022
pubmed:
22
3
2022
medline:
22
3
2022
Statut:
epublish
Résumé
Aluminum phosphide poisoning is one of the most common forms of poisoning which requires immediate and urgent treatment. This study aimed to compare the efficiency of two solutions, including hydroxyethyl starch and normal saline, in treating hypotension in patients with aluminum phosphide poisoning. This retrospective cohort study was conducted on 35 patients with aluminum phosphide poisoning. We reviewed the profile of 18 patients treated with hydroxyethyl starch and 17 patients treated with normal saline. Within-group and between-group differences in systolic blood pressure before and after treatment were compared using paired The mean ± standard deviation (SD) age of the subjects in the starch and normal saline groups was 27.06 ± 9.72 and 27.88 ± 9.08, respectively. The levels of blood pressure in the two groups were not significantly different before the treatment; the mean ± SD of systolic blood pressure in the starch and normal saline groups was 72.67 ± 14.49 and 68.59 ± 8.3, respectively ( According to the results of this study, although there was no significant difference between the two groups in terms of their effects on hypotension, these treatments could not prevent mortality.
Sections du résumé
Background
UNASSIGNED
Aluminum phosphide poisoning is one of the most common forms of poisoning which requires immediate and urgent treatment.
Objective
UNASSIGNED
This study aimed to compare the efficiency of two solutions, including hydroxyethyl starch and normal saline, in treating hypotension in patients with aluminum phosphide poisoning.
Methods
UNASSIGNED
This retrospective cohort study was conducted on 35 patients with aluminum phosphide poisoning. We reviewed the profile of 18 patients treated with hydroxyethyl starch and 17 patients treated with normal saline. Within-group and between-group differences in systolic blood pressure before and after treatment were compared using paired
Results
UNASSIGNED
The mean ± standard deviation (SD) age of the subjects in the starch and normal saline groups was 27.06 ± 9.72 and 27.88 ± 9.08, respectively. The levels of blood pressure in the two groups were not significantly different before the treatment; the mean ± SD of systolic blood pressure in the starch and normal saline groups was 72.67 ± 14.49 and 68.59 ± 8.3, respectively (
Conclusion
UNASSIGNED
According to the results of this study, although there was no significant difference between the two groups in terms of their effects on hypotension, these treatments could not prevent mortality.
Identifiants
pubmed: 35308654
doi: 10.1155/2022/4985120
pmc: PMC8926529
doi:
Types de publication
Journal Article
Langues
eng
Pagination
4985120Informations de copyright
Copyright © 2022 Amin Nakhostin-Ansari et al.
Déclaration de conflit d'intérêts
The authors declare that there are no conflicts of interest regarding the publication of this article.
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