Efficient Cholesterol Transport in Dendritic Cells Defines Optimal Exogenous Antigen Presentation and Toxoplasma gondii Proliferation.
CHMP4b
Toxoplasma gondii
U18666A inhibitor
antigen presentation
cholesterol
dendritic cells
intraluminal vesicles
multivesicular bodies
Journal
Frontiers in cell and developmental biology
ISSN: 2296-634X
Titre abrégé: Front Cell Dev Biol
Pays: Switzerland
ID NLM: 101630250
Informations de publication
Date de publication:
2022
2022
Historique:
received:
16
12
2021
accepted:
10
02
2022
entrez:
21
3
2022
pubmed:
22
3
2022
medline:
22
3
2022
Statut:
epublish
Résumé
Dendritic cells are the most powerful antigen-presenting cells of the immune system. They present exogenous antigens associated with Major Histocompatibility Complex (MHC) Class II molecules through the classical pathway to stimulate CD4+ T cells, or with MHC-I to activate CD8+ T lymphocytes through the cross-presentation pathway. DCs represent one of the main cellular targets during infection by
Identifiants
pubmed: 35309938
doi: 10.3389/fcell.2022.837574
pii: 837574
pmc: PMC8931308
doi:
Types de publication
Journal Article
Langues
eng
Pagination
837574Informations de copyright
Copyright © 2022 Croce, Garrido, Dinamarca, Santi-Rocca, Marion, Blanchard, Mayorga and Cebrian.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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