Effects of High-Frequency Oscillatory Ventilation With Volume Guarantee During Surfactant Treatment in Extremely Low Gestational Age Newborns With Respiratory Distress Syndrome: An Observational Study.
ELGAN
HFOV
lung recruitment
respiratory distress syndrome
volume guarantee
Journal
Frontiers in pediatrics
ISSN: 2296-2360
Titre abrégé: Front Pediatr
Pays: Switzerland
ID NLM: 101615492
Informations de publication
Date de publication:
2021
2021
Historique:
received:
29
10
2021
accepted:
28
12
2021
entrez:
21
3
2022
pubmed:
22
3
2022
medline:
22
3
2022
Statut:
epublish
Résumé
To evaluate the effect of volume guarantee (VG) combined with high-frequency oscillatory ventilation (HFOV) on respiratory and other physiological parameters immediately after lung recruitment and surfactant administration in HFOV elective ventilated extremely low gestational age newborns (ELGAN) with respiratory distress syndrome (RDS). Observational study. Tertiary neonatal intensive care unit. Twenty-two ELGANs of 25.5 ± 1.1 weeks of gestational age requiring invasive mechanical ventilation and surfactant administration for RDS during the first 6 h of life. All infants intubated in delivery room, were managed with elective HFOV and received surfactant after a lung recruitment manoeuver. Eleven infants received HFOV + VG and were compared with a control group of 11 infants receiving HFOV alone. HFOV was delivered in both groups by Dräger Babylog VN500 ventilator (Dräger, Lubeck, Germany). Variations and fluctuations of delivered high-frequency tidal volume (VT There were no significant differences in the two groups at starting ventilation with or without VG. The mean applied VT HFOV + VG maintains pCO
Identifiants
pubmed: 35310140
doi: 10.3389/fped.2021.804807
pmc: PMC8927884
doi:
Types de publication
Journal Article
Langues
eng
Pagination
804807Informations de copyright
Copyright © 2022 Tana, Paladini, Tirone, Aurilia, Lio, Bottoni, Costa, Tiberi, Pastorino and Vento.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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