The Ottawa 3DY Predicts Mortality in a Prospective Cohort Study.
Ottawa 3DY
cognitive screening test
cohort study
mortality
Journal
Canadian geriatrics journal : CGJ
ISSN: 1925-8348
Titre abrégé: Can Geriatr J
Pays: Canada
ID NLM: 101579189
Informations de publication
Date de publication:
Mar 2022
Mar 2022
Historique:
entrez:
21
3
2022
pubmed:
22
3
2022
medline:
22
3
2022
Statut:
epublish
Résumé
The Ottawa 3DY (O3DY) is a simple measure of cognition. 1) To determine if the O3DY predicts mortality; and 2) To compare the discrimination of the O3DY to the Mini-Mental State Examination (MMSE) and Modified MMSE (3MS). Analyses of a population based cohort study of 1,751 participants aged 65+; conducted in 1991/2 with follow-up over five years. The O3DY, age, sex, education, comorbid conditions, the MMSE, and the 3MS were measured: 4.5% of the participants had missing data for the O3DY; 42.8% were considered as positive (one or more errors), and 52.7% were considered as negative (no errors). Logistic regression models were constructed with the outcome of death at time 2. A Receiver Operator Curve (ROC) was constructed and the Area Under the ROC (AUROC) was calculated using a c-statistic. The unadjusted odds ratio (OR) and 95% confidence interval (CI) for mortality was 1.96 (1.56, 2.47); and the adjusted OR was 1.33 (1.02, 1.72). The AUROC was 0.66 for the 3MS, 0.65 for the MMSE, and 0.60 for the O3DY. The O3DY predicts mortality over a long time frame, although the discrimination is less than that of longer measures of cognition.
Sections du résumé
Background
UNASSIGNED
The Ottawa 3DY (O3DY) is a simple measure of cognition.
Objectives
UNASSIGNED
1) To determine if the O3DY predicts mortality; and 2) To compare the discrimination of the O3DY to the Mini-Mental State Examination (MMSE) and Modified MMSE (3MS).
Methods
UNASSIGNED
Analyses of a population based cohort study of 1,751 participants aged 65+; conducted in 1991/2 with follow-up over five years. The O3DY, age, sex, education, comorbid conditions, the MMSE, and the 3MS were measured: 4.5% of the participants had missing data for the O3DY; 42.8% were considered as positive (one or more errors), and 52.7% were considered as negative (no errors). Logistic regression models were constructed with the outcome of death at time 2. A Receiver Operator Curve (ROC) was constructed and the Area Under the ROC (AUROC) was calculated using a c-statistic.
Results
UNASSIGNED
The unadjusted odds ratio (OR) and 95% confidence interval (CI) for mortality was 1.96 (1.56, 2.47); and the adjusted OR was 1.33 (1.02, 1.72). The AUROC was 0.66 for the 3MS, 0.65 for the MMSE, and 0.60 for the O3DY.
Conclusions
UNASSIGNED
The O3DY predicts mortality over a long time frame, although the discrimination is less than that of longer measures of cognition.
Identifiants
pubmed: 35310474
doi: 10.5770/cgj.25.525
pii: cgj-25-66
pmc: PMC8887707
doi:
Types de publication
Journal Article
Langues
eng
Pagination
66-71Informations de copyright
© 2022 Author(s). Published by the Canadian Geriatrics Society.
Déclaration de conflit d'intérêts
CONFLICT OF INTEREST DISCLOSURES Dr. St John is an unremunerated member of the Board of Age and Opportunity (Manitoba), and has received speaking fees from the Regional Geriatric Program of Eastern Ontario. Dr. Molnar is the originator of the O3DY; he developed it and first published it. Neither author has a financial interest in the O3DY. The O3DY is intended for open use, and Dr. Molnar does not hold copyright. Drs. St John and Molnar have been colleagues and friends for many years.
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