COVID-19: autoimmunity, multisystemic inflammation and autoimmune rheumatic patients.

Autoimmunity COVID-19 SARS-CoV-2 drug repurposing multisystemic inflammatory syndrome rheumatic and musculoskeletal diseases vaccination

Journal

Expert reviews in molecular medicine
ISSN: 1462-3994
Titre abrégé: Expert Rev Mol Med
Pays: England
ID NLM: 100939725

Informations de publication

Date de publication:
15 03 2022
Historique:
entrez: 21 3 2022
pubmed: 22 3 2022
medline: 25 3 2022
Statut: epublish

Résumé

Coronavirus disease 2019 (COVID-19) is associated with autoimmunity and systemic inflammation. Patients with autoimmune rheumatic and musculoskeletal disease (RMD) may be at high risk for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. In this review, based on evidence from the literature, as well as international scientific recommendations, we review the relationships between COVID-19, autoimmunity and patients with autoimmune RMDs, as well as the basics of a multisystemic inflammatory syndrome associated with COVID-19. We discuss the repurposing of pharmaceutics used to treat RMDs, the principles for the treatment of patients with autoimmune RMDs during the pandemic and the main aspects of vaccination against SARS-CoV-2 in autoimmune RMD patients.

Identifiants

pubmed: 35311631
doi: 10.1017/erm.2022.10
pii: S1462399422000102
pmc: PMC8943223
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

e13

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Auteurs

Zoltán Szekanecz (Z)

Division of Rheumatology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.

Attila Balog (A)

Department of Rheumatology and Immunology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary.

Tamás Constantin (T)

2nd Department of Paediatrics, Faculty of Medicine, Semmelweis University, Budapest, Hungary.

László Czirják (L)

Department of Rheumatology and Immunology, Faculty of Medicine, University of Pécs, Pécs, Hungary.

Pál Géher (P)

Department of Rheumatology and Clinical Immunology, Semmelweis University, Budapest, Hungary.

László Kovács (L)

Department of Rheumatology and Immunology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary.

Gábor Kumánovics (G)

Department of Rheumatology and Immunology, Faculty of Medicine, University of Pécs, Pécs, Hungary.

György Nagy (G)

Departments of Rheumatology and Clinical Immunology, Genetics, Cell and Immunobiology and Internal Medicine and Oncology, Semmelweis University, Budapest, Hungary.

Éva Rákóczi (É)

Division of Rheumatology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.

Szilvia Szamosi (S)

Division of Rheumatology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.

Gabriella Szűcs (G)

Division of Rheumatology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.

István Vályi-Nagy (I)

National Institute of Haematology and Infectious Diseases, Budapest, Hungary.

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