First XEN implantation in Axenfeld- Rieger syndrome: A case report and literature review.
Axenfeld-Rieger syndrome
Case report
MIGS
Secondary childhood glaucoma
XEN implant
Journal
American journal of ophthalmology case reports
ISSN: 2451-9936
Titre abrégé: Am J Ophthalmol Case Rep
Pays: United States
ID NLM: 101679941
Informations de publication
Date de publication:
Jun 2022
Jun 2022
Historique:
received:
28
10
2021
revised:
06
03
2022
accepted:
08
03
2022
entrez:
22
3
2022
pubmed:
23
3
2022
medline:
23
3
2022
Statut:
epublish
Résumé
To present the first report of a XEN45 gel stent implantation in a female with Axenfeld-Rieger syndrome (ARS), a rare congenital anomaly caused by abnormal neural crest migration during early embryogenesis. This shows promise as new minimally invasive therapeutic option in the treatment of secondary glaucoma in ARS. A 31-year-old female with known sporadic ARS was evaluated and treated at the Edith Wolfson Medical Center in Holon, Israel. The vision in her right eye was hand motion and 20/25 in the left eye. In the left eye the intraocular pressure (IOP) was up to 31 mmHg under maximal tolerated treatment. She refused Trabeculectomy or Glaucoma Drainage Device (GDD) surgery, but agreed to Minimally Invasive Glaucoma Surgery (MIGS). A Xen device was implanted in uneventful surgery. 15 months post operatively her IOP is 8 mmHg. XEN implantation, when technically feasible, is a suitable procedure in ARS. This shows promise as new minimally invasive therapeutic option in the treatment of secondary glaucoma in ARS. This has particular significance as these patients often require surgery at a young age.
Identifiants
pubmed: 35313473
doi: 10.1016/j.ajoc.2022.101486
pii: S2451-9936(22)00232-8
pmc: PMC8933667
doi:
Types de publication
Case Reports
Langues
eng
Pagination
101486Informations de copyright
© 2022 The Authors.
Déclaration de conflit d'intérêts
All authors have no financial disclosures: LM, RE, LN, MKL.
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