In Vitro Confirmation of Artemisinin Resistance in Plasmodium falciparum from Patient Isolates, Southern Rwanda, 2019.
Kelch-13 gene mutations
Plasmodium falciparum
Rwanda
antimicrobial resistance
artemisinin resistance
malaria
parasites
vector-borne infections
Journal
Emerging infectious diseases
ISSN: 1080-6059
Titre abrégé: Emerg Infect Dis
Pays: United States
ID NLM: 9508155
Informations de publication
Date de publication:
04 2022
04 2022
Historique:
entrez:
23
3
2022
pubmed:
24
3
2022
medline:
2
4
2022
Statut:
ppublish
Résumé
Artemisinin resistance in Plasmodium falciparum is conferred by mutations in the kelch 13 (K13) gene. In Rwanda, K13 mutations have increased over the past decade, including mutations associated with delayed parasite clearance. We document artemisinin resistance in P. falciparum patient isolates from Rwanda carrying K13 R561H, A675V, and C469F mutations.
Identifiants
pubmed: 35318931
doi: 10.3201/eid2804.212269
pmc: PMC8962885
doi:
Substances chimiques
Antimalarials
0
Artemisinins
0
Protozoan Proteins
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
852-855Références
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