Are apolipoprotein E fragments a promising new therapeutic target for Alzheimer's disease?
Alzheimer’s disease
antisense oligonucleotides
apolipoprotein E
dementia
fragments
proteolysis
tau protein
therapeutics
Journal
Therapeutic advances in chronic disease
ISSN: 2040-6223
Titre abrégé: Ther Adv Chronic Dis
Pays: United States
ID NLM: 101532140
Informations de publication
Date de publication:
2022
2022
Historique:
received:
27
10
2021
accepted:
28
01
2022
entrez:
24
3
2022
pubmed:
25
3
2022
medline:
25
3
2022
Statut:
epublish
Résumé
Human apolipoprotein E (ApoE) is a 299-amino acid secreted glycoprotein that binds cholesterol and phospholipids. ApoE exists as three common isoforms (ApoE2, ApoE3, and ApoE4) and heterozygous carriers of the
Identifiants
pubmed: 35321401
doi: 10.1177/20406223221081605
pii: 10.1177_20406223221081605
pmc: PMC8935560
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
20406223221081605Informations de copyright
© The Author(s), 2022.
Déclaration de conflit d'intérêts
Conflict of interest statement: The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
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