Low hematocrit reduces the efficiency of CD34
blood center operations
therapeutic apheresis
transplantation - stem cell
Journal
Transfusion
ISSN: 1537-2995
Titre abrégé: Transfusion
Pays: United States
ID NLM: 0417360
Informations de publication
Date de publication:
05 2022
05 2022
Historique:
revised:
07
02
2022
received:
22
11
2021
accepted:
09
02
2022
pubmed:
25
3
2022
medline:
11
5
2022
entrez:
24
3
2022
Statut:
ppublish
Résumé
CD34 We retrospectively collected the data from 147 consecutive apheresis procedures across 106 healthy donors and 27 patients completed between July 2016 and December 2020 at the Okayama University Hospital. All procedures were performed using the Optia cMNC protocol. The median CD34 These data revealed the negative impact of low hematocrit on the efficiency of CD34
Sections du résumé
BACKGROUND
CD34
STUDY DESIGN AND METHODS
We retrospectively collected the data from 147 consecutive apheresis procedures across 106 healthy donors and 27 patients completed between July 2016 and December 2020 at the Okayama University Hospital. All procedures were performed using the Optia cMNC protocol.
RESULTS
The median CD34
CONCLUSION
These data revealed the negative impact of low hematocrit on the efficiency of CD34
Substances chimiques
Antigens, CD34
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1065-1072Informations de copyright
© 2022 AABB.
Références
Ljungman P, Bregni M, Brune M, Cornelissen J, de Witte T, Dini G, et al. Allogeneic and autologous transplantation for haematological diseases, solid tumours and immune disorders: current practice in Europe 2009. Bone Marrow Transplant. 2010;45(2):219-34.
Copelan EA. Hematopoietic stem-cell transplantation. N Engl J Med. 2006;14:1813-26.
DiPersio JF, Micallef IN, Stiff PJ, Bolwell BJ, Maziarz RT, Jacobsen E, et al. Phase III prospective randomized double-blind placebo-controlled trial of Plerixafor plus granulocyte Colony-stimulating factor compared with placebo plus granulocyte Colony-stimulating factor for autologous stem-cell mobilization and transplantation for patients with non-Hodgkin's lymphoma. J Clin Oncol. 2009;27(28):4767-73.
Lee S-N, Sohn JY, Kong JH, Eom HS, Lee H, Kong S-Y. Comparison of two apheresis systems of COBE and Optia for autologous peripheral blood stem cell collection. Ann Lab Med. 2017;37(4):327-30.
Bartnik K, Maciejewska M, Farhan R, Urbanowska E, Król M, Król M, et al. Continuous mononuclear cell collection (cMNC) protocol impact on hematopoietic stem cell collections in donors with negative collection predictors. Transfus Apher Sci. 2018;57(3):401-5.
Lisenko K, Pavel P, Bruckner T, Puthenparambil J, Hundemer M, Schmitt A, et al. Comparison between intermittent and continuous Spectra Optia leukapheresis systems for autologous peripheral blood stem cell collection: intermittent and continuous leukapheresis with Spectra Optia. J Clin Apher. 2017;32(1):27-34.
Ali S, Chiang K, Even-Or E, Di Mola M, Schechter T, Ali M, et al. Comparison between intermittent and continuous leukapheresis protocols for autologous hematopoietic stem cell collections in children. J Clin Apher. 2019;34(6):646-55.
Ford CD, Pace N, Lehman C. Factors affecting the efficiency of collection of CD34-positive peripheral blood cells by a blood cell separator. Transfusion. 1998;38(11-12):1046-50.
Remberger M, Törlén J, Ringdén O, Engström M, Watz E, Uhlin M, et al. Effect of Total nucleated and CD34+ cell dose on outcome after allogeneic hematopoietic stem cell transplantation. Biol Blood Marrow Transplant. 2015;21(5):889-93.
Rosenbaum ER, O'connell B, Cottler-Fox M. Validation of a formula for predicting daily CD34+ cell collection by leukapheresis. Cytotherapy. 2012;14(4):461-6.
Pierelli L, Maresca M, Piccirillo N, Pupella S, Gozzer M, Foddai ML, et al. Accurate prediction of autologous stem cell apheresis yields using a double variable-dependent method assures systematic efficiency control of continuous flow collection procedures. Vox Sang. 2006;91(2):126-34.
Hosing C, Saliba RM, Hamerschlak N, Kutner JM, Sakashita AM, Kondo AT, et al. Peripheral blood stem cell yield calculated using preapheresis absolute CD34+ cell count, peripheral blood volume processed, and donor body weight accurately predicts actual yield at multiple centers: prediction of stem cell yield. Transfusion. 2014;54(4):1081-7.
Cousins AF, Sinclair JE, Alcorn MJ, H A Green R, Douglas KW. HPC-A dose prediction on the optia® cell separator based on a benchmark CE2 collection efficiency: promoting clinical efficiency, minimizing toxicity, and allowing quality control: CE2-based dose prediction on Optia. J Clin Apher. 2015;30(6):321-8.
Verlinden A, Van de Velde A, Verpooten GA, Janssen van Doorn K. Determining factors predictive of CD34+ cell collection efficiency in an effort to avoid extended and repeated apheresis sessions: predicting CD34+ cell collection efficiency. J Clin Apher. 2013;28(6):404-10.
Leberfinger DL, Badman KL, Roig JM, Loos T. Improved planning of leukapheresis endpoint with customized prediction algorithm: minimizing collection days, volume of blood processed, procedure time, and citrate toxicity. Transfusion. 2017;57(3):685-93.
Ono Y, Yoshioka S, Inoue K, Yoshida M, Maruoka H, Ishikawa T. Stochastic model based on preharvest peripheral CD34-positive cell count and collection efficiency predicting processed blood volume in peripheral hematopoietic stem cell apheresis. Transfusion. 2019;59(2):671-80.
AraciM S, Kondo AT, Yokoyama APH, Lira SMC, Bub CB, Souza AM, et al. The impact of preapheresis white blood cell count on autologous peripheral blood stem cell collection efficiency and HSC infusion side effect rate. J Clin Apher. 2018;33(3):331-41.
Sutherland DR, Anderson L, Keeney M, Nayar R, Chin-Yee I. The ISHAGE guidelines for CD34+ cell determination by flow cytometry. J Hematother. 1996;5(3):213-26.
Cancelas JA, Scott EP, Bill JR. Continuous CD34+ cell collection by a new device is safe and more efficient than by a standard collection procedure: results of a two-center, crossover, randomized trial. Transfusion. 2016;56(11):2824-32.
Evans JD. Straightforward statistics for the behavioral sciences. Pacific Grove: Brooks/Cole Pub. Co.; 1996.
Godbey EA, Dormesy S, Gowda L, Nandi V, Paradiso S, Sachais BS, et al. A dual strategy to optimize hematopoietic progenitor cell collections: validation of a simple prediction algorithm and use of collect flow rates guided by mononuclear cell count. Transfusion. 2019;59(2):659-70.
Spoerl S, Wäscher D, Nagel S, Peschel C, Verbeek M, Götze K, et al. Evaluation of the new continuous mononuclear cell collection protocol versus an older version on two different apheresis machines. Transfusion. 2018;58(7):1772-80.
Sanderson F, Poullin P, Smith R, Nicolino-Brunet C, Philip P, Chaib A, et al. Peripheral blood stem cells collection on Spectra Optia apheresis system using the continuous mononuclear cell collection protocol: a single center report of 39 procedures: peripheral blood stem cells collection. J Clin Apher. 2017;32(3):182-90.
Pandey S, Cottler-Fox M. Optia® continuous mononuclear collection (CMNC) system is a safe and efficient system for hematopoietic progenitor cells-apheresis (HPC-a) collection and yields a lower product hematocrit (HCT%) than the COBE® spectra system: a retrospective study. J Clin Apher. 2018;33(4):505-13.
Cherqaoui B, Rouel N, Auvrignon A, Defachelles A-S, Deméocq F, Kanold J, et al. Peripheral blood stem cell collection in low-weight children: retrospective comparison of two apheresis devices: apheresis devices in low-weight children. Transfusion. 2014;54(5):1371-8.
Cooling L, Hoffmann S, Herrst M, Muck C, Armelagos H, Davenport R. A prospective randomized trial of two popular mononuclear cell collection sets for autologous peripheral blood stem cell collection in multiple myeloma. Transfusion. 2010;50(1):100-19.
Gidron A, Verma A, Doyle M, Boggio L, Evens A, Gordon L, et al. Can the stem cell mobilization technique influence CD34+ cell collection efficiency of leukapheresis procedures in patients with hematologic malignancies? Bone Marrow Transplant. 2005;35(3):243-6.
Punzel M, Kozlova A, Quade A, Schmidt AH, Smith R. Evolution of MNC and lymphocyte collection settings employing different Spectra Optia® leukapheresis systems. Vox Sang. 2017;112(6):586-94.
Sanford K, Roseff SD, Anderson J, Chung HM, McPherson RA. Harvesting autologous stem cells from a patient with red blood cell abnormalities of β-thalassemia intermedia: stem cell collection with hemoglobinopathies. Transfusion. 2014;54(7):1881-6.
Meldgaard Knudsen L, Nikolaisen K, Gaarsdal E, Johnsen HE. Kinetic studies during peripheral blood stem cell collection show CD34+ cell recruitment intra-apheresis. J Clin Apher. 2001;16(3):114-9.
Azzouqa A-GM, Jouni K, Roy V, Zubair AC. Impact of good and poor mobilizers on hematopoietic progenitor cell collection efficiency and product quality. J Clin Apher. 2019;34(1):39-43.