What Should Be the Topics of a Prospective Study on Ovarian Masses in Children?-Results of a Multicenter Retrospective Study and a Scoping Literature Review.

child evidence-based practice ovarian cysts ovarian masses ovarian neoplasms prospective studies quality improvement scoping study therapeutics

Journal

Current oncology (Toronto, Ont.)
ISSN: 1718-7729
Titre abrégé: Curr Oncol
Pays: Switzerland
ID NLM: 9502503

Informations de publication

Date de publication:
28 02 2022
Historique:
received: 25 01 2022
revised: 19 02 2022
accepted: 25 02 2022
entrez: 24 3 2022
pubmed: 25 3 2022
medline: 15 4 2022
Statut: epublish

Résumé

to determine management problems of ovarian masses in girls in order to form a baseline for prospective randomized studies of the established topics and quality improvement of our management. We performed a national analysis of clinical aspects of ovarian masses in girls operated on in Poland, analyzed retrospectively medical files of all consecutive patients aged 0-18 who underwent surgeries for ovarian lesions between 2012 and 2017 at 17 pediatric surgical departments and complemented the analysis with a scoping review of a recent primary research related to ovarian masses in children. The study group comprised 595 patients. Forty-four (7.39%) girls were diagnosed with malignant tumors. The overall preservation rate was 64.54%. The analysis revealed that positive tumor markers (OR = 10.3), lesions larger than 6 cm (OR = 4.17) and solid mass on ultrasound examination (OR = 5.34) are interdependent variables differentiating malignant tumors from non-malignant lesions (X42 = 79.1; We have developed an overview of the field with the emphasis on the local environment. Our next step is a multi-institutional prospective study of a quality improvement project implementation based on the obtained knowledge.

Identifiants

pubmed: 35323325
pii: curroncol29030125
doi: 10.3390/curroncol29030125
pmc: PMC8946882
doi:

Substances chimiques

Biomarkers, Tumor 0

Types de publication

Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

1488-1500

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Auteurs

Justyna Łuczak (J)

Pediatric Surgery and Urology Department, Wroclaw Medical University, 50-367 Wrocław, Poland.

Maciej Bagłaj (M)

Department of Propedeutic of Pediatrics and Rare Diseases, Wroclaw Medical University, 50-367 Wrocław, Poland.

Piotr Dryjański (P)

Pediatric Surgery and Urology Department, Wroclaw Medical University, 50-367 Wrocław, Poland.

Alicja Kalcowska (A)

Pediatric Surgery and Urology Department, Wroclaw Medical University, 50-367 Wrocław, Poland.
Pediatric Surgery Department, Dolnośląski Szpital Specjalistyczny im. T. Marciniaka, 54-049 Wrocław, Poland.

Nastazja Banaszyk-Pucała (N)

Department of Pediatric Surgery, Urology and Traumatology, Poznan University of Medical Sciences, 61-701 Poznań, Poland.

Maria Boczar (M)

Clinic of Pediatric Surgery, Institute of Mother and Child, 01-211 Warszawa, Poland.

Krzysztof Dymek (K)

Department of General and Oncological Pediatric Surgery for Children and Adolescents, Nicolaus Copernicus University, Ludwik Rydygier Collegium Medicum, 85-067 Bydgoszcz, Poland.

Małgorzata Fryczek (M)

Pediatric Surgery Department, Jagiellonian University Medical College, 31-008 Kraków, Poland.

Kaja Giżewska-Kacprzak (K)

Department of Pediatric and Oncological Surgery, Urology and Hand Surgery, Pomeranian Medical University, 70-204 Szczecin, Poland.

Wojciech Górecki (W)

Pediatric Surgery Department, Jagiellonian University Medical College, 31-008 Kraków, Poland.

Andrzej Grabowski (A)

Department of Children Developmental Defects and Traumatology, Medical University of Silesia, 40-055 Katowice, Poland.

Anna Gregor (A)

Pediatric Surgery and Urology Department, Zielona Góra Medical University, 65-046 Zielona Góra, Poland.

Maria Jabłońska (M)

Department of Pediatric Surgery and Organ Transplantation, The Children's Memorial Health Institute, 04-730 Warszawa, Poland.

Grzegorz Kowalewski (G)

Department of Pediatric Surgery and Organ Transplantation, The Children's Memorial Health Institute, 04-730 Warszawa, Poland.

Magdalena Lewandowska (M)

Department of Pediatric Surgery and Oncology, Central University Hospital, Medical University of Lodz, 90-647 Łódź, Poland.

Maria Małowiecka (M)

Pediatric Surgery Department, Children's Hospital in Dziekanów Leśny, 05-092 Dziekanów Leśny, Poland.

Anna Ogorzałek (A)

Pediatric Surgery and Urology Clinic, Medical College of Rzeszów University, 65-959 Rzeszów, Poland.

Magdalena Pękalska (M)

Chair and Department of Pediatric Surgery and Traumatology, Medical University of Lublin, 20-059 Lublin, Poland.

Aneta Piotrowska-Gall (A)

Department of Pediatric Surgery, Urology and Traumatology, Collegium Medicum, Jan Kochanowski University, 25-369 Kielce, Poland.

Mateusz Porębski (M)

Pediatric Surgery and Urology Clinic, Medical University of Silesia, 40-055 Katowice, Poland.

Marek Siewiński (M)

Pediatric Surgery Department, Opole University Hospital, 45-052 Opole, Poland.

Dariusz Patkowski (D)

Pediatric Surgery and Urology Department, Wroclaw Medical University, 50-367 Wrocław, Poland.

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