Effects of Environmental Heat Load on Endocannabinoid System Components in Adipose Tissue of High Yielding Dairy Cows.
2-AG
AEA
CB1
PPAR-α
TRPV1
adipose tissue
dairy cows
endocannabinoids
heat stress
Journal
Animals : an open access journal from MDPI
ISSN: 2076-2615
Titre abrégé: Animals (Basel)
Pays: Switzerland
ID NLM: 101635614
Informations de publication
Date de publication:
21 Mar 2022
21 Mar 2022
Historique:
received:
13
02
2022
revised:
16
03
2022
accepted:
17
03
2022
entrez:
25
3
2022
pubmed:
26
3
2022
medline:
26
3
2022
Statut:
epublish
Résumé
Environmental heat load (HL) adversely affects the performance of dairy cows. The endocannabinoid system (ECS) regulates metabolism and the stress response, thus we hypothesized that HL may affect the ECS of dairy cows. Our objective was to determine the levels of endocannabinoids (eCBs) and gene and protein expressions of the ECS components in adipose tissue (AT) and plasma of early postpartum (PP) and late-lactation cows. In addition, we examined eCBs in milk, and studied the interaction of eCBs with bovine cannabinoids receptors CB1 and CB2. In the first experiment, plasma and AT were sampled from cows calving during summer (S,
Identifiants
pubmed: 35327191
pii: ani12060795
doi: 10.3390/ani12060795
pmc: PMC8944798
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Israeli Dairy Board
ID : 362-0580
Organisme : BARD, The United States - Israel Binational Agricultural Research and Development Fund
ID : IS-5167-19
Références
J Dairy Sci. 2013 Sep;96(9):5656-69
pubmed: 23871373
Animal. 2020 Mar 16;:1-9
pubmed: 32172713
J Chem Inf Model. 2021 Dec 27;61(12):5742-5746
pubmed: 34780173
Science. 1992 Dec 18;258(5090):1946-9
pubmed: 1470919
Am J Neurodegener Dis. 2012;1(1):1-14
pubmed: 22737633
J Dairy Sci. 2019 Oct;102(10):9468-9480
pubmed: 31400898
J Dairy Sci. 2009 Mar;92(3):935-42
pubmed: 19233786
J Dairy Sci. 2015 Mar;98(3):1815-27
pubmed: 25547301
Cardiovasc Res. 2002 Aug 15;55(3):619-25
pubmed: 12160959
Curr Pharm Biotechnol. 2020;21(6):502-515
pubmed: 31823700
Obesity (Silver Spring). 2010 Jan;18(1):55-62
pubmed: 19521349
Clin Chem. 2009 Apr;55(4):611-22
pubmed: 19246619
Bioeng Transl Med. 2021 Jun 11;6(3):e10234
pubmed: 34589606
PLoS One. 2017 Jul 31;12(7):e0181900
pubmed: 28759571
J Clin Invest. 2010 Aug;120(8):2953-66
pubmed: 20664173
Nat Rev Drug Discov. 2007 May;6(5):357-72
pubmed: 17464295
Mol Pharmacol. 2003 Apr;63(4):908-14
pubmed: 12644592
J Clin Endocrinol Metab. 2006 Aug;91(8):3171-80
pubmed: 16684820
J Biol Chem. 2021 Sep;297(3):101022
pubmed: 34332978
Bioinformation. 2012;8(2):81-6
pubmed: 22359440
J Dairy Sci. 2011 Jan;94(1):86-96
pubmed: 21183020
Reprod Domest Anim. 2018 Jun;53(3):769-775
pubmed: 29542183
Cell Metab. 2012 Aug 8;16(2):167-79
pubmed: 22841573
Trends Cogn Sci. 2011 Dec;15(12):576-84
pubmed: 22078931
Angew Chem Int Ed Engl. 2018 Mar 1;57(10):2580-2585
pubmed: 29314474
Animals (Basel). 2021 Apr 01;11(4):
pubmed: 33915761
J Dairy Sci. 2013 Jul;96(7):4079-93
pubmed: 23664343
Int J Mol Sci. 2018 Jan 03;19(1):
pubmed: 29301344
Mol Pharmacol. 2005 Dec;68(6):1524-33
pubmed: 16135784
Biochem Pharmacol. 1995 Jun 29;50(1):83-90
pubmed: 7605349
J Proteomics. 2017 Mar 31;158:52-61
pubmed: 28238905
Prostaglandins Other Lipid Mediat. 2015 Sep;121(Pt A):110-21
pubmed: 26115647
Neuropsychopharmacology. 2016 Jan;41(1):80-102
pubmed: 26068727
J Clin Invest. 2017 Nov 1;127(11):4148-4162
pubmed: 29035280
J Anim Sci Biotechnol. 2021 Mar 5;12(1):21
pubmed: 33663611
Diabetes. 2006 Nov;55(11):3053-60
pubmed: 17065342
Phytomedicine. 2021 Apr;84:153450
pubmed: 33611212
Neuropsychopharmacology. 2011 Dec;36(13):2750-61
pubmed: 21849983
J Anim Sci. 2014 Jul;92(7):3026-34
pubmed: 24879765
PLoS One. 2018 Nov 7;13(11):e0205996
pubmed: 30403679
Interdiscip Sci. 2014 Sep;6(3):167-75
pubmed: 25205494
Antioxidants (Basel). 2021 Jun 03;10(6):
pubmed: 34205039
Theriogenology. 2020 Jul 1;150:437-444
pubmed: 32173067
Anal Chem. 2014 Jan 21;86(2):1186-95
pubmed: 24377270
J Clin Invest. 2003 Aug;112(3):423-31
pubmed: 12897210
J Autism Dev Disord. 2019 Mar;49(3):1284-1288
pubmed: 30382443
Biochem Biophys Res Commun. 1995 Oct 4;215(1):89-97
pubmed: 7575630
Pathogens. 2021 May 24;10(6):
pubmed: 34074035
Front Endocrinol (Lausanne). 2018 Jul 31;9:420
pubmed: 30108548
Cell Metab. 2013 Apr 2;17(4):475-90
pubmed: 23562074
J Dairy Sci. 2020 Nov;103(11):10809-10822
pubmed: 32896401
Interdiscip Sci. 2012 Sep;4(3):183-9
pubmed: 23292691
Elife. 2020 Nov 19;9:
pubmed: 33210603
J Dairy Sci. 2007 Apr;90(4):1947-56
pubmed: 17369235
Neuroendocrinology. 2020;110(3-4):246-257
pubmed: 31141804
Immunol Res. 2011 Oct;51(1):26-38
pubmed: 21626285
Animals (Basel). 2019 Sep 16;9(9):
pubmed: 31527410