Corpuscular Fragility and Metabolic Aspects of Freshly Drawn Beta-Thalassemia Minor RBCs Impact Their Physiology and Performance Post Transfusion: A Triangular Correlation Analysis In Vitro and In Vivo.

biomarkers donor variation energy metabolism fragility purine metabolism red blood cells transfusion

Journal

Biomedicines
ISSN: 2227-9059
Titre abrégé: Biomedicines
Pays: Switzerland
ID NLM: 101691304

Informations de publication

Date de publication:
23 Feb 2022
Historique:
received: 11 01 2022
revised: 03 02 2022
accepted: 22 02 2022
entrez: 25 3 2022
pubmed: 26 3 2022
medline: 26 3 2022
Statut: epublish

Résumé

The clarification of donor variation effects upon red blood cell (RBC) storage lesion and transfusion efficacy may open new ways for donor-recipient matching optimization. We hereby propose a "triangular" strategy for studying the links comprising the transfusion chain-donor, blood product, recipient-as exemplified in two cohorts of control and beta-thalassemia minor (βThal

Identifiants

pubmed: 35327331
pii: biomedicines10030530
doi: 10.3390/biomedicines10030530
pmc: PMC8945797
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Alkmini T Anastasiadi (AT)

Department of Biology, Section of Cell Biology and Biophysics, School of Science, National and Kapodistrian University of Athens (NKUA), 15784 Athens, Greece.

Vasiliki-Zoi Arvaniti (VZ)

Department of Biology, Section of Cell Biology and Biophysics, School of Science, National and Kapodistrian University of Athens (NKUA), 15784 Athens, Greece.

Efthymios C Paronis (EC)

Center of Clinical, Experimental Surgery & Translational Research, Biomedical Research Foundation, Academy of Athens (BRFAA), 11527 Athens, Greece.

Nikolaos G Kostomitsopoulos (NG)

Center of Clinical, Experimental Surgery & Translational Research, Biomedical Research Foundation, Academy of Athens (BRFAA), 11527 Athens, Greece.

Konstantinos Stamoulis (K)

Hellenic National Blood Transfusion Centre, Acharnes, 13677 Athens, Greece.

Issidora S Papassideri (IS)

Department of Biology, Section of Cell Biology and Biophysics, School of Science, National and Kapodistrian University of Athens (NKUA), 15784 Athens, Greece.

Angelo D'Alessandro (A)

Department of Biochemistry and Molecular Genetics, School of Medicine, Anschutz Medical Campus, University of Colorado, Aurora, CO 80045, USA.

Anastasios G Kriebardis (AG)

Laboratory of Reliability and Quality Control in Laboratory Hematology (HemQcR), Department of Biomedical Sciences, School of Health & Welfare Sciences, University of West Attica (UniWA), 12243 Egaleo, Greece.

Vassilis L Tzounakas (VL)

Department of Biology, Section of Cell Biology and Biophysics, School of Science, National and Kapodistrian University of Athens (NKUA), 15784 Athens, Greece.

Marianna H Antonelou (MH)

Department of Biology, Section of Cell Biology and Biophysics, School of Science, National and Kapodistrian University of Athens (NKUA), 15784 Athens, Greece.

Classifications MeSH