(Auto)Antibody Responses Shape Memory NK Cell Pool Size and Composition.
CD16
HCMV
auto-antibodies
immune thrombocytopenia (ITP)
memory natural killer (NK) cells
Journal
Biomedicines
ISSN: 2227-9059
Titre abrégé: Biomedicines
Pays: Switzerland
ID NLM: 101691304
Informations de publication
Date de publication:
08 Mar 2022
08 Mar 2022
Historique:
received:
14
02
2022
revised:
02
03
2022
accepted:
04
03
2022
entrez:
25
3
2022
pubmed:
26
3
2022
medline:
26
3
2022
Statut:
epublish
Résumé
In vivo establishment and long-term persistence of a heterogeneous memory or an adaptive NK cell pool represents a functional adaptation to human cytomegalovirus (HCMV) infection in humans. Memory NK cells are commonly identified by lack of the FcεRIγ signalling chain, variably associated to the preferential but not completely overlapping expression of the HLA-E receptor NKG2C and CD57 maturation marker. Although characterized by selective hyperresponsiveness to IgG stimulation, the impact of the CD16/antibody interaction in regulating the establishment/maintenance and size, and in determining the relative abundance of this population, is still under investigation. Memory NK cell subset ex vivo profile and in vitro responsiveness to CD16 stimulation was evaluated in HCMV
Identifiants
pubmed: 35327427
pii: biomedicines10030625
doi: 10.3390/biomedicines10030625
pmc: PMC8945707
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Sapienza University of Rome
ID : RP120172B81E572F; AR21916B74238026
Références
Oncoimmunology. 2017 Feb 10;6(3):e1290037
pubmed: 28405525
Front Immunol. 2021 Mar 12;12:624687
pubmed: 33777006
Immunity. 1998 Jun;8(6):693-701
pubmed: 9655483
Front Immunol. 2018 May 11;9:1031
pubmed: 29867997
Nat Rev Immunol. 2020 Feb;20(2):113-127
pubmed: 31666730
Nat Immunol. 2018 May;19(5):453-463
pubmed: 29632329
J Immunol. 1999 Jan 15;162(2):735-42
pubmed: 9916693
Blood. 2010 Nov 11;116(19):3865-74
pubmed: 20733159
Proc Natl Acad Sci U S A. 2011 Sep 6;108(36):14725-32
pubmed: 21825173
Immunology. 2022 Feb;165(2):234-249
pubmed: 34775592
J Exp Med. 2018 Sep 3;215(9):2379-2395
pubmed: 30061358
Trends Immunol. 2016 Jul;37(7):451-461
pubmed: 27160662
Cell Rep. 2016 May 3;15(5):1088-1099
pubmed: 27117418
Nat Rev Immunol. 2022 Feb;22(2):112-123
pubmed: 34117484
Front Cell Infect Microbiol. 2020 Mar 25;10:102
pubmed: 32269968
Int Immunol. 2012 Dec;24(12):793-802
pubmed: 22962434
J Immunol. 2020 Dec 15;205(12):3429-3442
pubmed: 33188073
Blood Adv. 2019 Dec 10;3(23):3829-3866
pubmed: 31794604
Platelets. 2017 Nov;28(7):728-730
pubmed: 28287032
J Exp Med. 2021 Apr 5;218(4):
pubmed: 33755720
J Immunol. 1991 Oct 15;147(8):2652-6
pubmed: 1833456
N Engl J Med. 2019 Sep 5;381(10):945-955
pubmed: 31483965
Annu Rev Immunol. 2021 Apr 26;39:417-447
pubmed: 33902312
Front Microbiol. 2019 Oct 04;10:2297
pubmed: 31636622
Autoimmun Rev. 2019 Mar;18(3):306-311
pubmed: 30639645
Trends Immunol. 2016 Mar;37(3):233-243
pubmed: 26869205
J Immunol. 1995 Jan 15;154(2):491-9
pubmed: 7814862
Int J Mol Sci. 2020 Nov 23;21(22):
pubmed: 33238550
PLoS Pathog. 2014 Oct 16;10(10):e1004441
pubmed: 25329659
Front Immunol. 2019 Dec 06;10:2865
pubmed: 31867015
JCI Insight. 2019 Jan 24;4(2):
pubmed: 30674718
J Immunol. 2012 Nov 15;189(10):5082-8
pubmed: 23077239
J Exp Med. 1995 Jan 1;181(1):339-44
pubmed: 7528771
Blood. 2012 Mar 15;119(11):2665-74
pubmed: 22180440
J Immunol. 2013 Feb 15;190(4):1402-6
pubmed: 23345329
J Immunol. 2017 Jan 1;198(1):94-101
pubmed: 27913630
Leukemia. 2016 Feb;30(2):456-63
pubmed: 26416461
J Immunol. 2014 Feb 15;192(4):1471-9
pubmed: 24442432
J Autoimmun. 2017 Sep;83:22-30
pubmed: 28285736
Immunity. 2015 Mar 17;42(3):431-42
pubmed: 25786175
Cell Rep. 2018 Aug 21;24(8):1967-1976.e4
pubmed: 30134159
Immunity. 2015 Mar 17;42(3):443-56
pubmed: 25786176
iScience. 2020 Oct 20;23(11):101709
pubmed: 33205022
Front Immunol. 2013 Dec 09;4:422
pubmed: 24367364
Eur J Immunol. 2021 Jul;51(7):1566-1579
pubmed: 33899224
Semin Immunol. 2014 Apr;26(2):145-51
pubmed: 24666761
Cytokine Growth Factor Rev. 2018 Aug;42:37-46
pubmed: 30122459
J Immunol Res. 2019 Feb 6;2019:8795673
pubmed: 30882007
Annu Rev Immunol. 2013;31:227-58
pubmed: 23516982