First-Trimester Screening for Fetal Growth Restriction and Small-for-Gestational-Age Pregnancies without Preeclampsia Using Cardiovascular Disease-Associated MicroRNA Biomarkers.

cardiovascular microRNAs early pregnancy fetal growth restriction gene expression prediction screening small for gestational age whole peripheral venous blood

Journal

Biomedicines
ISSN: 2227-9059
Titre abrégé: Biomedicines
Pays: Switzerland
ID NLM: 101691304

Informations de publication

Date de publication:
19 Mar 2022
Historique:
received: 19 01 2022
revised: 15 03 2022
accepted: 16 03 2022
entrez: 25 3 2022
pubmed: 26 3 2022
medline: 26 3 2022
Statut: epublish

Résumé

The goal of the study was to determine the early diagnostical potential of cardiovascular disease-associated microRNAs for prediction of small-for-gestational-age (SGA) and fetal growth restriction (FGR) without preeclampsia (PE). The whole peripheral venous blood samples were collected within 10 to 13 weeks of gestation from singleton Caucasian pregnancies within the period November 2012 to March 2020. The case-control retrospective study, nested in a cohort, involved all pregnancies diagnosed with SGA (

Identifiants

pubmed: 35327520
pii: biomedicines10030718
doi: 10.3390/biomedicines10030718
pmc: PMC8945808
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Charles University
ID : SVV no. 260386
Organisme : Charles University
ID : PROGRES Q34

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Auteurs

Ilona Hromadnikova (I)

Department of Molecular Biology and Cell Pathology, Third Faculty of Medicine, Charles University, 100 00 Prague, Czech Republic.

Katerina Kotlabova (K)

Department of Molecular Biology and Cell Pathology, Third Faculty of Medicine, Charles University, 100 00 Prague, Czech Republic.

Ladislav Krofta (L)

Institute for the Care of the Mother and Child, Third Faculty of Medicine, Charles University, 147 00 Prague, Czech Republic.

Classifications MeSH