Cell Therapy Based on Gingiva-Derived Mesenchymal Stem Cells Seeded in a Xenogeneic Collagen Matrix for Root Coverage of RT1 Gingival Lesions: An In Vivo Experimental Study.
cell therapy
gingiva-derived stem cells
gingival recession
mesenchymal stem cells
mesenchymal stromal cells
root coverage
soft tissue regeneration
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
17 Mar 2022
17 Mar 2022
Historique:
received:
11
02
2022
revised:
12
03
2022
accepted:
15
03
2022
entrez:
25
3
2022
pubmed:
26
3
2022
medline:
9
4
2022
Statut:
epublish
Résumé
(1) Background: To investigate the effect of a xenogeneic collagen matrix (CMX) seeded with autologous gingiva-derived mesenchymal cells (GMSCs) when combined with a coronally advanced flap (CAF) in the treatment of localized gingival recession type 1 (RT1). (2) Methods: Dehiscence-type defects were created in seven dogs. GMSCs were isolated, transfected with a vector carrying green fluorescent protein (GFP) and expanded. Once chronified, the defects were randomly treated with (1) CAF plus the combination of CMX and GFP
Identifiants
pubmed: 35328670
pii: ijms23063248
doi: 10.3390/ijms23063248
pmc: PMC8950013
pii:
doi:
Substances chimiques
Collagen
9007-34-5
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Osteology Foundation
ID : 12-063
Références
Int J Periodontics Restorative Dent. 1985;5(2):8-13
pubmed: 3858267
Int J Periodontics Restorative Dent. 2012 Jun;32(3):273-82
pubmed: 22408772
Periodontol 2000. 2013 Oct;63(1):198-216
pubmed: 23931061
Nat Rev Nephrol. 2018 Aug;14(8):493-507
pubmed: 29895977
J Clin Periodontol. 2013 Jul;40(7):713-20
pubmed: 23627374
J Periodontal Res. 2015 Jun;50(3):363-70
pubmed: 25040690
J Periodontal Res. 2012 Feb;47(1):33-44
pubmed: 21906056
J Clin Periodontol. 2020 Nov;47(11):1403-1415
pubmed: 32654220
J Periodontol. 2005 Jun;76(6):881-9
pubmed: 15948681
Stem Cells Dev. 2011 Apr;20(4):647-59
pubmed: 20712449
J Dent Res. 2019 Oct;98(11):1195-1203
pubmed: 31381868
J Clin Periodontol. 2013 Jan;40(1):82-9
pubmed: 23050490
J Clin Periodontol. 2017 Jan;44(1):96-103
pubmed: 27790732
J Clin Periodontol. 2009 Jun;36(6):523-31
pubmed: 19508251
J Dent (Shiraz). 2017 Jun;18(2):95-103
pubmed: 28620633
J Clin Periodontol. 2011 Sep;38(9):847-55
pubmed: 21770997
J Clin Periodontol. 2007 Mar;34(3):262-8
pubmed: 17309597
J Periodontol. 2010 Apr;81(4):616-25
pubmed: 20367104
Clin Oral Investig. 2016 Dec;20(9):2539-2549
pubmed: 26917493
Nat Immunol. 2014 Nov;15(11):1009-16
pubmed: 25329189
Int J Periodontics Restorative Dent. 2008 Oct;28(5):461-7
pubmed: 18990997
J Periodontol. 2013 Oct;84(10):1416-24
pubmed: 23259414
Altern Lab Anim. 2005 Dec;33(6):591-601
pubmed: 16372834
J Clin Periodontol. 2014 Apr;41 Suppl 15:S123-42
pubmed: 24640997
J Clin Periodontol. 2019 Jun;46 Suppl 21:162-182
pubmed: 30623455
J Biomater Appl. 2016 Jul;31(1):121-31
pubmed: 27009932
J Periodontol. 2016 Mar;87(3):221-7
pubmed: 26469812
J Stem Cells. 2014;9(4):253-67
pubmed: 25942341
J Clin Periodontol. 2019 Oct;46(10):1013-1023
pubmed: 31292987
Cytotherapy. 2006;8(4):315-7
pubmed: 16923606
J Clin Periodontol. 2020 Nov;47(11):1391-1402
pubmed: 32946590
Clin Oral Investig. 2017 May;21(4):1095-1102
pubmed: 27270903
World J Stem Cells. 2019 Sep 26;11(9):604-617
pubmed: 31616538
J Clin Periodontol. 2018 Jan;45(1):78-88
pubmed: 29087001
J Clin Periodontol. 2018 Jun;45 Suppl 20:S190-S198
pubmed: 29926504
Mater Sci Eng C Mater Biol Appl. 2015 May;50:19-23
pubmed: 25746240