A Histone Deacetylase (HDAC) Inhibitor with Pleiotropic In Vitro Anti-
HDACi
IC50
Plasmodium
anti-Toxoplasma drug
mice
treatment
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
17 Mar 2022
17 Mar 2022
Historique:
received:
24
02
2022
revised:
14
03
2022
accepted:
16
03
2022
entrez:
25
3
2022
pubmed:
26
3
2022
medline:
9
4
2022
Statut:
epublish
Résumé
Toxoplasmosis is a highly prevalent human disease, and virulent strains of this parasite emerge from wild biotopes. Here, we report on the potential of a histone deacetylase (HDAC) inhibitor we previously synthesized, named JF363, to act in vitro against a large panel of
Identifiants
pubmed: 35328672
pii: ijms23063254
doi: 10.3390/ijms23063254
pmc: PMC8952293
pii:
doi:
Substances chimiques
Histone Deacetylase Inhibitors
0
Histone Deacetylases
EC 3.5.1.98
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Références
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