Cognitive Function among World Trade Center-Exposed Community Members with Mental Health Symptoms.


Journal

International journal of environmental research and public health
ISSN: 1660-4601
Titre abrégé: Int J Environ Res Public Health
Pays: Switzerland
ID NLM: 101238455

Informations de publication

Date de publication:
15 03 2022
Historique:
received: 18 02 2022
revised: 10 03 2022
accepted: 11 03 2022
entrez: 25 3 2022
pubmed: 26 3 2022
medline: 19 4 2022
Statut: epublish

Résumé

The World Trade Center Environmental Health Center (WTC EHC), is a federally designated clinical center of excellence for surveillance and treatment of WTC disaster exposed community members (WTC Survivors). Cognitive impairment (CI) has been extensively described in WTC responders and a concern for progressive impairment in all WTC disaster exposed groups has been raised. Cognitive status, however, has not been systematically characterized in the WTC Survivor population. We describe cognitive status in a subgroup of the Survivor population referred for mental health evaluation (N = 480) in the WTC EHC as measured by scores on the Montreal Cognitive Assessment (MoCA) instrument, and examine their association with WTC exposures and individual-level covariates including PTSD and depression screening inventory scores. In regression analyses, probable cognitive impairment (MoCA score < 26) was found in 59% of the study subjects and was significantly associated with age, race/ethnicity, education, income, depression and PTSD scores. Being caught in the dust cloud on 11 September 2011 was significantly associated with cognitive impairment even after controlling for the above. These data suggest an association with cognitive dysfunction in WTC Survivors with exposure to the toxic dust/fumes and psychological stress from the 9/11 terrorist attack and warrant further systematic study.

Identifiants

pubmed: 35329128
pii: ijerph19063440
doi: 10.3390/ijerph19063440
pmc: PMC8948727
pii:
doi:

Substances chimiques

Dust 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NIA NIH HHS
ID : P30 AG066512
Pays : United States
Organisme : NIA NIH HHS
ID : P01AG060882
Pays : United States
Organisme : NIA NIH HHS
ID : P30AG066512
Pays : United States

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Auteurs

Rebecca Rosen (R)

Department of Psychiatry, NYU Grossman School of Medicine, New York, NY 10016, USA.
World Trade Center Environmental Health Center, NYC Health+Hospitals, New York, NY 10016, USA.

Yongzhao Shao (Y)

World Trade Center Environmental Health Center, NYC Health+Hospitals, New York, NY 10016, USA.
Department of Environmental Medicine, NYU Grossman School of Medicine, New York, NY 10016, USA.
Department of Population Health, NYU Grossman School of Medicine, New York, NY 10016, USA.
NYU Alzheimer's Disease Research Center, New York, NY 10016, USA.

Qiao Zhang (Q)

World Trade Center Environmental Health Center, NYC Health+Hospitals, New York, NY 10016, USA.
Department of Population Health, NYU Grossman School of Medicine, New York, NY 10016, USA.

Jia Bao (J)

World Trade Center Environmental Health Center, NYC Health+Hospitals, New York, NY 10016, USA.
Department of Population Health, NYU Grossman School of Medicine, New York, NY 10016, USA.

Yian Zhang (Y)

World Trade Center Environmental Health Center, NYC Health+Hospitals, New York, NY 10016, USA.
Department of Population Health, NYU Grossman School of Medicine, New York, NY 10016, USA.

Arjun Masurkar (A)

NYU Alzheimer's Disease Research Center, New York, NY 10016, USA.
Department of Neurology, NYU Grossman School of Medicine, New York, NY 10016, USA.

Thomas Wisniewski (T)

NYU Alzheimer's Disease Research Center, New York, NY 10016, USA.
Department of Neurology, NYU Grossman School of Medicine, New York, NY 10016, USA.

Nina Urban (N)

Department of Psychiatry, NYU Grossman School of Medicine, New York, NY 10016, USA.
World Trade Center Environmental Health Center, NYC Health+Hospitals, New York, NY 10016, USA.

Joan Reibman (J)

World Trade Center Environmental Health Center, NYC Health+Hospitals, New York, NY 10016, USA.
Department of Environmental Medicine, NYU Grossman School of Medicine, New York, NY 10016, USA.
Department of Medicine, NYU Grossman School of Medicine, New York, NY 10016, USA.

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