Biological Mechanisms behind Wischnewsky Spots Finding on Gastric Mucosa: Autopsy Cases and Literature Review.
Wischnewsky spots
agony
autopsy
biology
hypothermia
ketoacidosis
stomach
Journal
International journal of environmental research and public health
ISSN: 1660-4601
Titre abrégé: Int J Environ Res Public Health
Pays: Switzerland
ID NLM: 101238455
Informations de publication
Date de publication:
18 03 2022
18 03 2022
Historique:
received:
22
12
2021
revised:
11
03
2022
accepted:
15
03
2022
entrez:
25
3
2022
pubmed:
26
3
2022
medline:
19
4
2022
Statut:
epublish
Résumé
Hypothermia is an emergency caused by the lowering of the central body temperature with a slowdown of basic vital functions. Reduced mobility, old age, psychiatric or metabolic disorders are relevant risk factors. Diagnosis of death from hypothermia is a challenge, as there are no pathognomonic signs, and supportive findings can be inconstant. Wischnewsky Spots (WS) are blackish lesions of gastric mucosa, typically associated with hypothermic death. The pathophysiology of these lesions is still uncertain. The aim of this paper is to investigate the pathological mechanisms determining the appearance of WS by analyzing the current scientific knowledge in this area. We performed a narrative review of the literature published in the last 20 years, comparing the results with three cases of hypothermia reported from our experience. The review proved that WS show a multifactorial etiology, i.e., not only body temperature decrease, but also various extrinsic and intrinsic factors, such as physical and psychological stress, agony,
Identifiants
pubmed: 35329287
pii: ijerph19063601
doi: 10.3390/ijerph19063601
pmc: PMC8955028
pii:
doi:
Types de publication
Case Reports
Review
Langues
eng
Sous-ensembles de citation
IM
Références
Int J Legal Med. 2014 Jul;128(4):607-14
pubmed: 24557588
Am J Forensic Med Pathol. 2006 Mar;27(1):70-4
pubmed: 16501354
BMJ Open. 2021 Oct 28;11(10):e052200
pubmed: 34711600
Exp Gerontol. 1985;20(3-4):201-9
pubmed: 4065260
Sci Rep. 2020 Feb 5;10(1):1877
pubmed: 32024924
Med Leg J. 2016 Mar;84(1):52-5
pubmed: 25882507
J Forensic Leg Med. 2013 Aug;20(6):595-7
pubmed: 23910840
Clin Case Rep. 2021 May 06;9(8):
pubmed: 34466230
J Forensic Sci. 2020 Nov;65(6):2013-2018
pubmed: 32717145
J Forensic Leg Med. 2013 Aug;20(6):785-7
pubmed: 23910881
Physiol Behav. 1984 Feb;32(2):265-8
pubmed: 6538982
Physiol Behav. 2004 Oct 15;82(5):827-33
pubmed: 15451646
Am J Forensic Med Pathol. 2018 Sep;39(3):279-281
pubmed: 29401111
JAMA. 2021 Oct 19;326(15):1494-1503
pubmed: 34665203
Leg Med (Tokyo). 1999 Dec;1(4):204-9
pubmed: 12935470
J Comp Pathol. 2021 Jul;186:18-22
pubmed: 34340800
Am J Forensic Med Pathol. 2016 Sep;37(3):165-9
pubmed: 27356011
Int J Legal Med. 2017 Nov;131(6):1639-1641
pubmed: 28698894
Forensic Sci Med Pathol. 2013 Mar;9(1):88-90
pubmed: 22585458
Forensic Sci Int. 2008 Apr 7;176(2-3):248-52
pubmed: 18006258
Arch Kriminol. 2016 Nov;238(5-6):188-197
pubmed: 29465867
Med Sci Law. 2014 Jul;54(3):177-80
pubmed: 24166686
Forensic Sci Int. 2007 Jul 4;169(2-3):220-2
pubmed: 16650950
J Forensic Leg Med. 2014 Feb;22:30-2
pubmed: 24485417
Am J Forensic Med Pathol. 2019 Jun;40(2):188-191
pubmed: 30475235
Forensic Sci Int. 2020 Sep;314:110397
pubmed: 32668371
Am J Forensic Med Pathol. 2019 Jun;40(2):192-195
pubmed: 30676335
Med Sci Law. 1964 Jan;4:44-6
pubmed: 14106767