Challenges in the Diagnosis and Management of Fibrotic Hypersensitivity Pneumonitis: A Practical Review of Current Approaches.
hypersensitivity pneumonitis
interstitial lung disease
lung fibrosis
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
08 Mar 2022
08 Mar 2022
Historique:
received:
31
12
2021
revised:
23
02
2022
accepted:
04
03
2022
entrez:
25
3
2022
pubmed:
26
3
2022
medline:
26
3
2022
Statut:
epublish
Résumé
Recent advances in fibrotic hypersensitivity pneumonitis include improved diagnostic guidance, systematic assessments of immunosuppressive therapy, and the recent availability of antifibrotic therapy (nintedanib) for those with progressive disease. A standardized approach to diagnosis may lead to better inclusion criteria for future therapeutic protocols and delineation of disease or treatment response predictors for real-world management. This review will highlight current diagnostic and treatment challenges and remaining knowledge gaps or areas of uncertainty, with a practical overview of supporting evidence and its clinical implications. Exposure history, serologic testing for antigen sensitivity, bronchoalveolar lavage lymphocytosis, histopathology, and radiologic findings will be covered in the diagnosis section, with immunosuppression, antifibrotic therapy, lung transplantation, and disease prognosis in the treatment and management section.
Identifiants
pubmed: 35329800
pii: jcm11061473
doi: 10.3390/jcm11061473
pmc: PMC8955902
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Références
Lung. 2019 Feb;197(1):113-114
pubmed: 30552500
Semin Respir Crit Care Med. 2012 Oct;33(5):543-54
pubmed: 23001807
Am Rev Respir Dis. 1992 Jan;145(1):3-5
pubmed: 1731594
Mod Pathol. 2020 Apr;33(4):616-625
pubmed: 31659276
Am J Respir Crit Care Med. 2019 Nov 1;200(9):1154-1163
pubmed: 31268371
Eur Respir J. 2021 Mar 4;57(3):
pubmed: 33122338
Chest. 1997 Mar;111(3):534-6
pubmed: 9118683
Jpn J Radiol. 2020 Jun;38(6):524-532
pubmed: 32103467
Am J Respir Crit Care Med. 2001 Sep 15;164(6):1025-32
pubmed: 11587991
Respir Med. 2017 Aug;129:173-178
pubmed: 28732828
Histopathology. 2012 Dec;61(6):1026-35
pubmed: 22882269
Curr Opin Allergy Clin Immunol. 2013 Apr;13(2):151-8
pubmed: 23403644
Sarcoidosis Vasc Diffuse Lung Dis. 2016 Aug 01;33(2):117-23
pubmed: 27537713
Chest. 2016 Jun;149(6):1473-81
pubmed: 26836921
J Allergy Clin Immunol. 1991 May;87(5):1002-9
pubmed: 1902851
J Clin Pathol. 2013 Oct;66(10):888-95
pubmed: 23881224
Heart Lung. 2021 May-Jun;50(3):407-416
pubmed: 33621839
Chest. 2008 Oct;134(4):844-850
pubmed: 18842917
Respir Investig. 2015 Sep;53(5):217-24
pubmed: 26344611
Am J Respir Crit Care Med. 2020 Aug 1;202(3):e36-e69
pubmed: 32706311
Allergol Int. 2021 Apr;70(2):208-214
pubmed: 33041192
Chest. 2021 Aug;160(2):595-615
pubmed: 33865835
Chest. 2017 Mar;151(3):619-625
pubmed: 27816444
Respir Med Case Rep. 2018 Mar 22;24:25-29
pubmed: 29977751
Eur Radiol. 2012 Aug;22(8):1672-9
pubmed: 22466512
Eur Respir J. 2007 Apr;29(4):706-12
pubmed: 17182654
ERJ Open Res. 2020 Sep 28;6(3):
pubmed: 33015147
Am J Med. 2004 May 15;116(10):662-8
pubmed: 15121492
Clin Allergy. 1980 Jan;10(1):91-5
pubmed: 6988108
J Clin Invest. 1977 Jan;59(1):165-75
pubmed: 830661
BMC Pulm Med. 2021 Jul 19;21(1):243
pubmed: 34281549
Eur Respir J. 2020 Aug 6;56(2):
pubmed: 32265306
Am J Surg Pathol. 2009 Dec;33(12):1765-70
pubmed: 19809277
Am J Surg Pathol. 2017 Oct;41(10):1403-1409
pubmed: 28614213
Chest. 2013 Aug;144(2):586-592
pubmed: 23392130
Allergol Int. 2019 Jul;68(3):321-328
pubmed: 30737114
Am J Respir Crit Care Med. 2019 Aug 1;200(3):336-347
pubmed: 30566847
Eur Respir J. 1988 Jan;1(1):5-9
pubmed: 3284760
Pulm Pharmacol Ther. 2020 Feb;60:101878
pubmed: 31862300
Allergy. 2019 May;74(5):944-952
pubmed: 30515826
Hum Pathol. 2015 Apr;46(4):607-13
pubmed: 25694347
Chest. 1985 Oct;88(4):563-6
pubmed: 4042708
Am J Respir Crit Care Med. 2019 Aug 15;200(4):518
pubmed: 31051092
Am J Respir Crit Care Med. 2017 Nov 15;196(10):1249-1254
pubmed: 28414524
WMJ. 2019 Jul;118(2):95-97
pubmed: 31532937
Chest. 2014 Jun;145(6):1333-1338
pubmed: 24458311
Am J Respir Crit Care Med. 2017 Nov 27;197(8):1036-1044
pubmed: 29172641
Chest. 2014 Apr;145(4):723-728
pubmed: 24114524
Respir Investig. 2020 Jul;58(4):285-290
pubmed: 32265153
J Allergy Clin Immunol. 1984 Nov;74(5):719-27
pubmed: 6209321
Eur Radiol. 2017 Dec;27(12):5127-5135
pubmed: 28687910
Eur Respir J. 2020 Apr 23;55(4):
pubmed: 31949120
J Clin Med. 2018 Dec 21;8(1):
pubmed: 30577667
Eur Radiol. 2021 Jun;31(6):3993-4003
pubmed: 33241510
Respir Investig. 2021 Nov;59(6):845-848
pubmed: 34373236
Respir Res. 2021 May 20;22(1):152
pubmed: 34016104
Arch Pathol Lab Med. 2018 Jan;142(1):109-119
pubmed: 28537805
Semin Respir Crit Care Med. 2016 Jun;37(3):395-405
pubmed: 27231863
BMC Pulm Med. 2006 Jun 26;6:16
pubmed: 16800875
Pulmonology. 2020 Jan - Feb;26(1):3-9
pubmed: 31735689
Ann Am Thorac Soc. 2015 Jul;12(7):1013-21
pubmed: 26010749
Eur J Respir Dis. 1981 Oct;62(5):332-43
pubmed: 7047184
Chest. 2020 Jun;157(6):1506-1512
pubmed: 31958445
Respir Med. 2021 Aug;184:106444
pubmed: 33991845
Am Rev Respir Dis. 1979 Nov;120(5):985-94
pubmed: 315742
Inflamm Allergy Drug Targets. 2012 Feb;11(1):15-9
pubmed: 22309080
BMJ Open Respir Res. 2019 Dec 3;6(1):e000469
pubmed: 31803475
Eur Respir J. 2019 Jul 25;54(1):
pubmed: 31164428
Exp Lung Res. 1989 May;15(3):359-73
pubmed: 2787241
Respir Med. 2016 Mar;112:97-105
pubmed: 26831202
Chest. 1984 Apr;85(4):514-22
pubmed: 6231167
Scand J Clin Lab Invest. 2021 Oct;81(6):451-453
pubmed: 34278893
BMC Pulm Med. 2020 Jul 21;20(1):199
pubmed: 32693781
J Immunol. 1990 Oct 1;145(7):2147-54
pubmed: 2144545
Allergol Int. 2010 Jun;59(2):223-8
pubmed: 20414051
Lancet Respir Med. 2016 Jul;4(7):557-565
pubmed: 27180021
Arch Pathol Lab Med. 2008 Feb;132(2):204-5
pubmed: 18251577
Respir Med. 2021 Oct;187:106598
pubmed: 34481307
J Thorac Imaging. 2016 Mar;31(2):92-103
pubmed: 26479131
Lancet Respir Med. 2020 May;8(5):453-460
pubmed: 32145830
Cent Eur J Immunol. 2019;44(4):390-394
pubmed: 32140051
Ann Am Thorac Soc. 2017 Oct;14(10):1533-1538
pubmed: 28513215
Am J Respir Crit Care Med. 2019 May 15;199(10):1284-1287
pubmed: 30768910
Eur Respir J. 1990 Mar;3(3):359-61
pubmed: 2340897
Chest. 2015 Jun;147(6):1558-1565
pubmed: 25412059
J Allergy Clin Immunol Pract. 2016 May-Jun;4(3):537-8
pubmed: 26883542
Respir Res. 2021 Aug 10;22(1):225
pubmed: 34376172
Ann Am Thorac Soc. 2020 Nov;17(11):1455-1467
pubmed: 32757946
APMIS. 2019 Sep;127(9):616-626
pubmed: 31273840
Respirology. 2014 Aug;19(6):891-9
pubmed: 24890329
Am J Respir Crit Care Med. 2003 Oct 15;168(8):952-8
pubmed: 12842854
Ann Am Thorac Soc. 2018 Apr;15(4):460-469
pubmed: 29236517
Respir Med. 2011 Nov;105(11):1696-703
pubmed: 21824758
Respirology. 2015 Aug;20(6):947-52
pubmed: 26073170
Respiration. 2021;100(10):940-948
pubmed: 34515206
Respir Investig. 2020 Jan;58(1):52-58
pubmed: 31718936
BMC Pulm Med. 2022 Feb 1;22(1):49
pubmed: 35105320
ERJ Open Res. 2017 Aug 17;3(3):
pubmed: 28845429
Respir Res. 2021 Apr 23;22(1):120
pubmed: 33892724
Chest. 2013 Nov;144(5):1644-1651
pubmed: 23828161
Arch Bronconeumol (Engl Ed). 2020 Mar;56(3):163-169
pubmed: 31784348
Respir Investig. 2013 Sep;51(3):191-9
pubmed: 23978646
Mayo Clin Proc. 2007 Jul;82(7):812-6
pubmed: 17605960
N Engl J Med. 2019 Oct 31;381(18):1718-1727
pubmed: 31566307
Lung. 2018 Oct;196(5):617-622
pubmed: 29959521
Chest. 2019 Apr;155(4):699-711
pubmed: 30243979
Thorax. 2013 Aug;68(8):780-1
pubmed: 23515438
AJR Am J Roentgenol. 1995 Oct;165(4):807-11
pubmed: 7676971
Int Arch Allergy Immunol. 2009;149(2):161-6
pubmed: 19127074
BMJ Open Respir Res. 2021 Nov;8(1):
pubmed: 34794958