Prevalence of Opioid Use Disorder among Patients with Cancer-Related Pain: A Systematic Review.

cancer chronic pain meta-analysis opioid use disorder prevalence systematic review

Journal

Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588

Informations de publication

Date de publication:
14 Mar 2022
Historique:
received: 26 01 2022
revised: 03 03 2022
accepted: 10 03 2022
entrez: 25 3 2022
pubmed: 26 3 2022
medline: 26 3 2022
Statut: epublish

Résumé

The opioid use disorder is an international public health problem. Over the past 20 years it has been the subject of numerous publications concerning patients treated for chronic pain other than cancer-related. Patients with cancer-related pain are also at risk of opioid use disorder. The primary objective of this literature review was to determine the prevalence of opioid use disorder in patients with cancer-related chronic pain. Its secondary objective was to identify the characteristics of these opioid users. This is a literature review of studies published over the last twenty years, from 1 January 2000 to 31 December 2020 identified by searching the three main medical databases: Pubmed, Cochrane, and Embase. A meta-analysis took account of between and within-study variability with the use of random-effects models estimated by the DerSimonian and Laird method. The prevalence of opioid use disorder was 8% (1-20%) and of the risk of use disorder was 23.5% (19.5-27.8%) with Further studies are now needed on the prevalence of opioid use disorder in patients treated for cancer-related chronic pain. A screening scale adapted to this patient population is urgently needed.

Sections du résumé

BACKGROUND BACKGROUND
The opioid use disorder is an international public health problem. Over the past 20 years it has been the subject of numerous publications concerning patients treated for chronic pain other than cancer-related. Patients with cancer-related pain are also at risk of opioid use disorder. The primary objective of this literature review was to determine the prevalence of opioid use disorder in patients with cancer-related chronic pain. Its secondary objective was to identify the characteristics of these opioid users.
METHODS METHODS
This is a literature review of studies published over the last twenty years, from 1 January 2000 to 31 December 2020 identified by searching the three main medical databases: Pubmed, Cochrane, and Embase. A meta-analysis took account of between and within-study variability with the use of random-effects models estimated by the DerSimonian and Laird method.
RESULTS RESULTS
The prevalence of opioid use disorder was 8% (1-20%) and of the risk of use disorder was 23.5% (19.5-27.8%) with
CONCLUSIONS CONCLUSIONS
Further studies are now needed on the prevalence of opioid use disorder in patients treated for cancer-related chronic pain. A screening scale adapted to this patient population is urgently needed.

Identifiants

pubmed: 35329919
pii: jcm11061594
doi: 10.3390/jcm11061594
pmc: PMC8954099
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Références

J Pain Palliat Care Pharmacother. 2014 Mar;28(1):4-9
pubmed: 24417217
Contemp Clin Trials. 2015 Nov;45(Pt A):139-45
pubmed: 26343745
Pain Physician. 2017 Feb;20(2S):S93-S109
pubmed: 28226333
Cancer. 1999 Nov 1;86(9):1848-55
pubmed: 10547560
J Clin Epidemiol. 2012 Sep;65(9):934-9
pubmed: 22742910
PLoS One. 2013;8(4):e60600
pubmed: 23577131
Clin J Pain. 2006 Feb;22(2):173-81
pubmed: 16428952
Palliat Support Care. 2021 Feb;19(1):3-10
pubmed: 32729447
J Natl Cancer Inst. 2020 Sep 1;112(9):938-943
pubmed: 31845985
Acad Emerg Med. 2016 Feb;23(2):151-8
pubmed: 26824227
Nat Rev Clin Oncol. 2019 Apr;16(4):213-226
pubmed: 30514978
Pain Med. 2019 Dec 1;20(12):2552-2561
pubmed: 31197321
Support Care Cancer. 2014 Jul;22(7):1883-8
pubmed: 24563103
Oncologist. 2015 Jun;20(6):692-7
pubmed: 25933929
BMJ. 2003 Sep 6;327(7414):557-60
pubmed: 12958120
Acta Oncol. 1998;37(7-8):641-4
pubmed: 10050980
J Opioid Manag. 2019 Jul/Aug;15(4):272-274
pubmed: 31637679
Pain Physician. 2011 Mar-Apr;14(2):123-43
pubmed: 21412368
BMJ. 2021 Mar 29;372:n71
pubmed: 33782057
J Pain Symptom Manage. 2000 Apr;19(4):274-86
pubmed: 10799794
Pain Med. 2013 May;14(5):667-75
pubmed: 23631401
RMD Open. 2019 Aug 6;5(2):e001029
pubmed: 31452932
Expert Opin Drug Saf. 2019 Mar;18(3):211-217
pubmed: 30722706
J Pediatr Psychol. 2014 Nov-Dec;39(10):1149-60
pubmed: 25225182
Drugs. 2012 Dec 24;72(18):2327-32
pubmed: 23116252
Cancer. 2018 Oct 1;124(19):3942-3949
pubmed: 30192372
Curr Psychiatry Rep. 2009 Oct;11(5):377-84
pubmed: 19785979
Eur J Pain. 2007 Jul;11(5):490-518
pubmed: 17070082
Gynecol Oncol. 2017 Nov;147(2):456-459
pubmed: 28807366
BMJ Support Palliat Care. 2022 Mar;12(1):107-113
pubmed: 33355216
Am Soc Clin Oncol Educ Book. 2015;:e593-9
pubmed: 25993228

Auteurs

Céline Preux (C)

Palliative Care Center, CHU Clermont-Ferrand, F-63000 Clermont-Ferrand, France.

Marion Bertin (M)

Palliative Care Center, CHU Clermont-Ferrand, F-63000 Clermont-Ferrand, France.

Andréa Tarot (A)

Palliative Care Center, CHU Clermont-Ferrand, F-63000 Clermont-Ferrand, France.

Nicolas Authier (N)

Neuro-Dol, Service Pharmacologie Médicale, Centres d'Addictovigilance et Pharmacovigilance, Centre Evaluation et Traitement de la Douleur, Inserm, CHU Clermont-Ferrand, Université de Clermont Auvergne, F-63001 Clermont-Ferrand, France.
Institut Analgésia, Faculté de Médecine, BP38, F-63001 Clermont-Ferrand, France.
Observatoire Français des Médicaments Antalgiques/French Monitoring Centre for Analgesic Drugs, Université Clermont-Ferrand, F-63001 Clermont-Ferrand, France.

Nathalie Pinol (N)

Centre de Documentation et Recherche de la Faculté de Médecine, CHU Clermont-Ferrand, Université de Clermont Auvergne, F-63000 Clermont-Ferrand, France.

David Brugnon (D)

Palliative Care Center, CHU Clermont-Ferrand, F-63000 Clermont-Ferrand, France.

Bruno Pereira (B)

Unité de Biostatistiques, Direction de la Recherche Clinique et de l'Innovation, CHU Clermont-Ferrand, F-63000 Clermont-Ferrand, France.

Virginie Guastella (V)

Palliative Care Center, CHU Clermont-Ferrand, F-63000 Clermont-Ferrand, France.
Neuro-Dol, Service Pharmacologie Médicale, Centres d'Addictovigilance et Pharmacovigilance, Centre Evaluation et Traitement de la Douleur, Inserm, CHU Clermont-Ferrand, Université de Clermont Auvergne, F-63001 Clermont-Ferrand, France.

Classifications MeSH